• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Rac1 GTPase is a critical factor in phagocytosis in the large yellow croaker Larimichthys crocea by interacting with tropomyosin
Publication date: Available online 11 May 2019Source: Fish & Shellfish ImmunologyAuthor(s): Fang Han, Wanbo Li, Xiande Liu, Dongling Zhang, Lanping Liu, Zhiyong WangAbstractThe Rho family GTPase Rac1 acts as a molecular switch for signal transduction to regulate various cellular functions. Here, a Rac1 homolog (LcRac1) was identified in large yellow croaker (Larimichthys crocea), one of the most economically important marine fishes. The LcRac1 protein was expressed in Escherichia coli and purified. Subsequently the specific antibody was raised using the purified fusion protein (GST-LcRac1). LcRac1 was ubiquitously expresse...
Source: Fish and Shellfish Immunology - May 16, 2019 Category: Biology Source Type: research

Influence of various stressors on the expression of core genes of the small interfering RNA pathway in the oriental fruit fly, Bactrocera dorsalis
Abstract RNA interference (RNAi)‐based technology has emerged as a potential tool for controlling insect pests, however, previous studies found that the efficiency of RNAi in Bactrocera dorsalis was variable. In nature, insects often meet various challenges, such as pathogen infections, extreme temperatures, lack of nutrition and heavy metals. To better understand the association of the stressors with efficiency of RNAi, in the current study we tested the expression of three core genes, dicer2 (Bddcr2), r2d2 (Bdr2d2) and argonaute2 (Bdago2), of the small interfering RNA (siRNA) pathway of B. dorsalis upon various stresso...
Source: Insect Science - May 24, 2016 Category: Biology Authors: Yi‐Fei Xie, Jin‐Zhi Niu, Xuan‐Zhao Jiang, Wen‐Jia Yang, Guang‐Mao Shen, Dong Wei, Guy Smagghe, Jin‐Jun Wang Tags: ORIGINAL ARTICLE Source Type: research

Kaempferol targets Krt-14 and induces cytoskeletal mineralization in osteoblasts: A mechanistic approach
Publication date: Available online 5 March 2016 Source:Life Sciences Author(s): Vikram Khedgikar, Priyanka Kushwaha, Jyoti Gautam, Shewta Sharma, Ashwni Verma, Dharmendra Choudhary, Prabhat R. Mishra, Ritu Trivedi Kaempferol (KEM) has been observed to stimulate Krt-14 protein which subsequently contributes to matrix maturation and mineralization in rat primary osteoblast cells. Incorporation of Krt-14 siRNA results in reduced mRNA and protein expression after 48h post transfection and remained low for 9days. At day 9 Krt-14 siRNA significantly reduced mineralization without concomitant change in the cell number. ...
Source: Life Sciences - March 6, 2016 Category: Biology Source Type: research

Influence of various stressors to the expression of core genes of the small interfering RNA pathway in the oriental fruit fly, Bactrocera dorsalis (Hendel)
This article is protected by copyright. All rights reserved
Source: Insect Science - January 6, 2016 Category: Biology Authors: Yi‐Fei Xie, Jin‐Zhi Niu, Xuan‐Zhao Jiang, Wen‐Jia Yang, Guang‐Mao Shen, Dong Wei, Guy Smagghe, Jin‐Jun Wang Tags: ORIGINAL ARTICLE Source Type: research