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Protective effect of HSP27 in atherosclerosis and coronary heart disease by inhibiting reactive oxygen species
Conclusion: HSP27 exerts its protective role by suppressing ROS and AS progression through inhibiting mitochondria apoptosis pathway in CHD. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 12, 2017 Category: Biochemistry Authors: Hongli Zhang, Kaiying Jia, Da Sun, Min Yang Tags: Article Source Type: research

Molecular Mechanisms of Tributyltin ‐Induced Alterations in Cholesterol Homeostasis and Steroidogenesis in Hamster Testis: In Vivo and In Vitro Studies
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 12, 2017 Category: Biochemistry Authors: Kanimozhi V, Palanivel K, Akbarsha MA, Kadalmani B Tags: Article Source Type: research

Metformin inhibits tumorigenesis in HBV ‐induced hepatocellular carcinoma by suppressing HULC overexpression caused by HBX
Conclusion: This study indicated that metformin imposed inhibitory effect on the HBV‐associated HCC by negatively regulating the HULC /p18/miR‐200a/ZEB1 signaling pathway. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 12, 2017 Category: Biochemistry Authors: Zhen Jiang, Haichao Liu Tags: Article Source Type: research

Rs4705342 polymorphism is involved in the tumorigenesis of HBV positive HCC by altering the binding affinity of HBV induced NF ‐kB with the promoter region of microRNA‐143
Conclusion: The presence of the minor allele of rs4705342 in the promoter of miR‐143 attenuated the transcription ability. This promoted ORP8 expression and could be a factor contributing to the oncogenesis in HBV positive HCC. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 13, 2017 Category: Biochemistry Authors: Yin Xiuli, Sun Shiying, Zhao Junyan, Yang Jing, Lei Xiaofei, Xu Changqing, Li Kun Tags: Article Source Type: research

Proliferation and apoptosis of rheumatoid arthritis fibroblast ‐like synoviocytes following signal transducer and activator of transcription 3 RNA interference delivery
Conclusion: Transfection with targeted STAT3 recombinant plasmids effectively inhibited the expression of STAT3 mRNA and its protein in RA‐FLSs. RNAi‐mediated silencing of STAT3 reduced the proliferation and promoted the apoptosis of FLSs. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 13, 2017 Category: Biochemistry Authors: Xuehui Sun, Yun Han, Ying Liu, Yanchun Tang, Jibo Wang Tags: Article Source Type: research

Knockdown of Ski decreased the reactive astrocytes proliferation in vitro induced by oxygen ‐glucose deprivation/reoxygenation
This study is to elucidate the role of Ski in reactive astrocytes induced by oxygen‐glucose deprivation/reoxygenation (OGD/R) model in vitro. The expression of Ski was proved to be up‐regulated in OGD/R model. Meanwhile, Up‐regulation of Ski was accompanied with high ratio of EdU (+) cells and up‐expression of related proteins including GFAP, PCNA, CDK4 and CyclinD1, which demonstrated the distinct activation and proliferation of astrocytes after stimulation by OGD/R. Astrocytes were transfected with Ski‐specific siRNA to knockdown Ski expression and subsequently attenuated OGD‐induced astrocyte proliferation. ...
Source: Journal of Cellular Biochemistry - December 13, 2017 Category: Biochemistry Authors: Xin Zhao, Kai ‐Sheng Zhou, Zhong‐Hao Li, Wei Nan, Jing Wang, Ya‐Yi Xia, Hai‐Hong Zhang Tags: Article Source Type: research

MicroRNA ‐335‐5p Suppresses Lower Extremity Deep Venous Thrombosis by Targeted Inhibition of PAI‐1 via the TLR4 Signaling Pathway
Conclusion: miR‐335‐5p may suppress the occurrence and development of LEDVT in rats by repressing the activation of the TLR4 signaling pathway by targeted inhibition of PAI‐1. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 27, 2017 Category: Biochemistry Authors: Cui ‐Xia Bao, Dong‐Xia Zhang, Na‐Na Wang, Xiang‐Kui Zhu, Qi Zhao, Xiao‐Lei Sun Tags: Article Source Type: research

HMGB1 ‐induced asthmatic airway inflammation through GRP75‐mediated enhancement of ER–Mitochondrial Ca2+ transfer and ROS increased
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - January 2, 2018 Category: Biochemistry Authors: Lv Yanhua, Li Yanli, Zhang Dandan, Zhang Anbing, Guo Weihong, Zhu Shunfang Tags: Article Source Type: research

MicroRNA ‐494 regulates Gli3 expression and inhibits pancreatic cancer cells growth and migration
In conclusion, these data demonstrate miR‐494 exhibits tumor‐suppressive effects on pancreatic cancer, possibly via targeting Gli3. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - January 6, 2018 Category: Biochemistry Authors: Yongbiao Ma, Gaoxue Li, Jingxia Hu, Xin Liu, Baomin Shi Tags: Article Source Type: research

HMGB1 ‐induced asthmatic airway inflammation through GRP75‐mediated enhancement of ER‐mitochondrial Ca2+ transfer and ROS increased
Abstract Imbalanced T‐helper (TH)1/Th2 response contributes significantly to asthma pathogenesis. Our study indicated that HMGB1 play an important role in the release of Th2‐associated cytokines of asthma. However, the specific mechanism about HMGB1‐induced imbalanced TH1/Th2 response is not known. In vivo, an OVA‐induced asthma mouse model was set up and mice treated with anti‐HMGB1 IgG. The mice treated with the anti‐HMGB1 IgG ameliorated airway hyper‐reactivity, disruption of Th1/Th2 balance and the upregulation of GRP75 induced by OVA. In vitro, the exposure of normal human bronchial epithelial cells to H...
Source: Journal of Cellular Biochemistry - January 25, 2018 Category: Biochemistry Authors: Yanhua Lv, Yanli Li, Dandan Zhang, Anbing Zhang, Weihong Guo, Shunfang Zhu Tags: RESEARCH ARTICLE Source Type: research

Compound C induces protective autophagy in human cholangiocarcinoma cells via Akt/mTOR ‐independent pathway
In conclusion, suppresses autophagy could increase compound C sensitivity in human CCA. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - January 31, 2018 Category: Biochemistry Authors: Xiaofang Zhao, Guosong Luo, Ying Cheng, Wenjing Yu, Run Chen, Bin Xiao, Yuancai Xiang, Chunhong Feng, Wenguang Fu, Chunyan Duan, Fuli Yao, Xianming Xia, Qinghua Tao, Mei Wei, Rongyang Dai Tags: Article Source Type: research

Microgravity modulation of syncytin ‐A expression enhance osteoclast formation
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - February 1, 2018 Category: Biochemistry Authors: Purushoth Ethiraj, Jessica R. Link, James M. Sinkway, Gabriella D. Brown, William A. Parler, Sakamuri V. Reddy Tags: Article Source Type: research

Effects of HMGA2 gene downregulation by siRNA on lung carcinoma cell migration in A549 cell lines
Journal of Cellular Biochemistry, EarlyView.
Source: Journal of Cellular Biochemistry - October 14, 2018 Category: Biochemistry Authors: Sanaz Naghizadeh, Behzad Mansoori, Ali Mohammadi, Hossein Samadi Kafil, Zohreh Mousavi, Ebrahim Sakhinia, Behzad Baradaran Source Type: research

The oncolytic virus H101 combined with GNAQ siRNA ‐mediated knockdown reduces uveal melanoma cell viability
Journal of Cellular Biochemistry, EarlyView.
Source: Journal of Cellular Biochemistry - October 15, 2018 Category: Biochemistry Authors: Yongyun Li, Jie He, Chun Qiu, Qingfeng Shang, Guanxiang Qian, Xianqun Fan, Shengfang Ge, Renbing Jia Source Type: research

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