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Adamts1 Mediates Ethanol‐Induced Alterations in Collagen and Elastin via a FoxO1‐Sestrin3‐AMPK Signaling Cascade in Myocytes
A variety of stressors including alcohol (EtOH) are known to induce collagen production and fibrotic diseases. Matrix metalloproteinases (MMP) play an important role in regulating fibrosis, but little is known regarding the relationship between EtOH and MMPs. In addition, the signaling cascades involved in this process have not been elucidated. We have identified the MMP Adamts1 as a target of EtOH regulation. To characterize the function of Adamts1, we examined EtOH‐induced alterations in collagen I and elastin protein levels in C2C12 myocytes. Incubation of myocytes with 100 mM EtOH decreased elastin and increased co...
Source: Journal of Cellular Biochemistry - August 20, 2014 Category: Biochemistry Authors: Ly Q. Hong‐Brown, C. Randell Brown, Maithili Navaratnarajah, Charles H. Lang Tags: Research Article Source Type: research

A Novel Role of Annexin A2 in Human Type I Collagen Gene Expression
ABSTRACT The fibrillar collagen scaffold of the extracellular matrix provides a structural framework for cells in tissues and regulates intercellular communication; its disregulation has been associated with tumour development and progression. Previous work has shown that expression of type I collagen, the most abundant mammalian extracellular matrix protein, is decreased in chemically or virally transformed cells. This negative regulation could be mapped to a proximal COL1A2 promoter element spanning a CME (Collagen Modulating Element) site in SV40‐transformed human fibroblasts (SV‐WI38) that binds an unknown repressi...
Source: Journal of Cellular Biochemistry - October 8, 2014 Category: Biochemistry Authors: Georgia Schäfer, Jessica K. Hitchcock, Tamlyn M. Shaw, Arieh A. Katz, M. Iqbal Parker Tags: Article Source Type: research

Tumor necrosis factor‐α‐induced protein‐8 like‐2 (TIPE2) upregulates p27 to decrease gastic cancer cell proliferation
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Source: Journal of Cellular Biochemistry - December 24, 2014 Category: Biochemistry Authors: Qian Zhao, Min Zhao, Tianyi Dong, Chengjun Zhou, Yanping Peng, Xiangyu Zhou, Bingbing Fan, Wenzheng Ma, Mingyong Han, Shili Liu Tags: Article Source Type: research

Caveolae may enable albumin to enter human renal glomerular endothelial cells
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Source: Journal of Cellular Biochemistry - January 5, 2015 Category: Biochemistry Authors: Takahito Moriyama, Takashi Takei, Mitsuyo Itabashi, Keiko Uchida, Ken Tsuchiya, Kosaku Nitta Tags: Article Source Type: research

Caveolin‐1 Mediates Inflammatory Breast Cancer Cell Invasion via the Akt1 Pathway and RhoC GTPase
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Source: Journal of Cellular Biochemistry - January 5, 2015 Category: Biochemistry Authors: Madhura Joglekar, Weam O. Elbazanti, Matthew D. Weitzman, Heather L. Lehman, Kenneth L. van Golen Tags: Article Source Type: research

Spatiotemporal expression of EAPP modulates neuronal apoptosis and reactive astrogliosis after spinal cord injury
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Source: Journal of Cellular Biochemistry - February 21, 2015 Category: Biochemistry Authors: Minhao Chen, Yingjie Ni, Yonghua Liu, Xiaopeng Xia, Jianhua Cao, Chengniu Wang, Xingxing Mao, Weidong Zhang, Chen Chen, Xinlei Chen, Youhua Wang Tags: Article Source Type: research

Role of Sox9 in Growth Factor Regulation of Articular Chondrocytes
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Source: Journal of Cellular Biochemistry - February 24, 2015 Category: Biochemistry Authors: Shuiliang Shi, Congrong Wang, Anthony J. Acton, George J. Eckert, Stephen B. Trippel Tags: Article Source Type: research

Let‐7f Inhibits Glioma Cell Proliferation, Migration, and Invasion by Targeting Periostin
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Source: Journal of Cellular Biochemistry - March 3, 2015 Category: Biochemistry Authors: Shaofeng Yan, Xiao Han, Hao Xue, Ping Zhang, Xing Guo, Tong Li, Xiaofan Guo, Guang Yuan, Lin Deng, Gang Li Tags: Article Source Type: research

Oncostatin M Promotes Osteoblastic Differentiation of Human Vascular Smooth Muscle Cells through JAK3‐STAT3 Pathway
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Source: Journal of Cellular Biochemistry - March 3, 2015 Category: Biochemistry Authors: Yoshinori Kakutani, Atsushi Shioi, Tetsuo Shoji, Hirokazu Okazaki, Hidenori Koyama, Masanori Emoto, Masaaki Inaba Tags: Article Source Type: research

Gcn5 Modulates the Cellular Response to Oxidative Stress and Histone Deacetylase Inhibition
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Source: Journal of Cellular Biochemistry - March 9, 2015 Category: Biochemistry Authors: Ann‐Christin Gaupel, Thomas Begley, Martin Tenniswood Tags: Article Source Type: research

miR‐544 regulates dairy goat male germline stem cell self‐renewal via targeting PLZF
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Source: Journal of Cellular Biochemistry - March 24, 2015 Category: Biochemistry Authors: Wencong Song, Hailong Mu, Jiang Wu, Mingzhi Liao, Haijing Zhu, Liming Zheng, Xin He, Bowen Niu, Yuanxin Zhai, Chunling Bai, Anmin Lei, Guangpeng Li, Jinlian Hua Tags: Article Source Type: research

Global Gene Deregulations in FASN Silenced Retinoblastoma Cancer Cells: Molecular and Clinico‐Pathological Correlations
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Source: Journal of Cellular Biochemistry - May 8, 2015 Category: Biochemistry Authors: Manoharan Sangeetha, Perinkulam Ravi Deepa, Pukhraj Rishi, Vikas Khetan, Subramanian Krishnakumar Tags: Article Source Type: research

Selenoprotein S is highly expressed in the blood vessels and prevents vascular smooth muscle cells from apoptosis
In conclusion, the present study suggested that SelS highly expressed in the blood vessel might protect VSMCs from apoptosis by inhibiting oxidative stress and ER stress. Our finding provided mechanistic insights for the potential preventive role of SelS in atherosclerotic CVD. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - June 8, 2015 Category: Biochemistry Authors: Yali Ye, Fen Fu, Xiaoming Li, Jie Yang, Hongmei Liu Tags: Article Source Type: research

Numb Protects Human Renal Tubular Epithelial Cells from Bovine Serum Albumin‐Induced Apoptosis Through Antagonizing CHOP/PERK Pathway
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Source: Journal of Cellular Biochemistry - June 20, 2015 Category: Biochemistry Authors: Xuebing Ding, Mingming Ma, Junfang Teng, Erxi Wu, Xuejing Wang Tags: Research Article Source Type: research

PRDM1, a Tumor‐Suppressor Gene, is Induced by Genkwadaphnin in Human Colon Cancer SW620 Cells
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Source: Journal of Cellular Biochemistry - June 19, 2015 Category: Biochemistry Authors: Ho‐Bum Kang, Ha‐Reum Lee, Da Jung Jee, Su‐Hyun Shin, Seong‐Su Nah, Sun Young Yoon, Jae Wha Kim Tags: Research Article Source Type: research

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