Filtered By:
Drug: Magnesium
This page shows you your search results in order of relevance. This is page number 4.
Order by Relevance | Date
Total 77 results found since Jan 2013.
Tripartite motif protein 52 (TRIM52) promoted fibrosis in LX-2 cells through PPM1A-mediated Smad2/3 pathway.
This article is protected by copyright. All rights reserved.
PMID: 31329338 [PubMed - as supplied by publisher]
Source: Cell Biology International - July 21, 2019 Category: Cytology Authors: Zhou J, Lan Q, Li W, Yang L, You J, Zhang YM, Ni W Tags: Cell Biol Int Source Type: research
A Biodegradable Mg-Based Alloy Inhibited the Inflammatory Response of THP-1 Cell-Derived Macrophages Through the TRPM7 –PI3K–AKT1 Signaling Axis
Mg-based alloys might be ideal biomaterials in clinical applications owing to favorable mechanical properties, biodegradability, biocompatibility, and especially their anti-inflammatory properties. However, the precise signaling mechanism underlying the inhibition of inflammation by Mg-based alloys has not been elucidated. Here, we investigated the effects of a Mg-2.1Nd-0.2Zn-0.5Zr alloy (denoted as JDBM) on lipopolysaccharide (LPS)-induced macrophages. THP-1 cell-derived macrophages were cultured on JDBM, Ti−6Al−4V alloy (Ti), 15% extract of JDBM, and 7.5 mM of MgCl2 for 1 h before the addition of LPS for an indicated...
Source: Frontiers in Immunology - December 2, 2019 Category: Allergy & Immunology Source Type: research
Dentin Matrix Protein 1 Regulates Mineralization of MC3T3-E1 Cells via the TNAP-ANK-ENPP1 Axis
CONCLUSIONS: DMP1 regulated mineralization of MC3T3-E1 cells via the TNAP-ANK-ENPP1 axis and affected TNAP activity by two processes-rapid regulation of the Zn2+ transporter (ZnT) and transcriptional regulation of hysteresis. However, DMP1 may affect expression of ENPP1 and ANK only via hysteresis transcriptional regulation. DMP1, as a calcium trap or catalytic enzyme, appears to have a role in collagen mineralization.PMID:37380477 | DOI:10.1272/jnms.JNMS.2023_90-306
Source: Journal of Nippon Medical School - June 28, 2023 Category: Universities & Medical Training Authors: Jianmin Liu Juhua Zhao Zhi Li Hongmei Wang Binbin Wang Wei Liu Lei Zhou Source Type: research
