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Total 77 results found since Jan 2013.

Regulation of Chromatin Assembly and Cell Transformation by Formaldehyde Exposure in Human Cells
Conclusions: We propose that the inhibition of chromatin assembly represents a novel mechanism of cell transformation induced by the environmental and occupational chemical carcinogen FA. https://doi.org/10.1289/EHP1275 Received: 25 October 2016 Revised: 19 May 2017 Accepted: 23 May 2017 Published: 21 September 2017 Address correspondence to C. Jin, Dept. of Environmental Medicine, New York University School of Medicine, 57 Old Forge Rd., Tuxedo Park, NY 10987 USA. Telephone: (845) 731-3602. Email: Chunyuan.jin@nyumc.org *Current affiliation: Medical School of Nanjing University, Nanjing, China. †Current affiliatio...
Source: EHP Research - September 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

CCN1/Cyr61-PI3K/AKT signaling promotes retinal neovascularization in oxygen-induced retinopathy.
Abstract Retinal neovascularization (RNV) is a characteristic pathological finding of retinopathy of prematurity (ROP). Cysteine-rich 61 [Cyr61, also known as CCN family member 1 (CCN1)] has been reported to mediate angiogenesis. The aim of the present study was to investigate the mechanisms of CCN1/Cyr61-phosphoinositide 3-kinase (PI3K)/AKT signaling in ROP. The contribution of CCN1 to human umbilical vein endothelial cell (HUVEC) proliferation and apoptosis under hypoxic conditions was determined using a cell counting kit‑8 (CCK-8) and Annexin V/propidium iodide (PI) staining, respectively, as well as...
Source: International Journal of Molecular Medicine - October 12, 2015 Category: Molecular Biology Authors: Di Y, Zhang Y, Nie Q, Chen X Tags: Int J Mol Med Source Type: research

Polarization of THP-1-Derived Macrophage by Magnesium and MAGT1 Inhibition in Wound Healing
Conclusion Mg2+ can help to end the delay in wound healing caused by persistent inflammation in the early stages.PMID:37564721 | PMC:PMC10411119 | DOI:10.1055/s-0043-1770114
Source: Archives of Plastic Surgery - August 11, 2023 Category: Cosmetic Surgery Authors: Mun Ho Oh JaeHyuk Jang Jong Hun Lee Source Type: research