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Specialty: Pathology
Condition: Osteoporosis

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Total 2 results found since Jan 2013.

The miR-187 induced bone reconstruction and healing in a mouse model of osteoporosis, and accelerated osteoblastic differentiation of human multipotent stromal cells by targeting BARX2
CONCLUSIONS: The miR-187 might have a significant therapeutic effect in osteoporotic fractures. miR-187 accelerated osteogenic differentiation of hMSCs by directly regulating BARX2.PMID:33550149 | DOI:10.1016/j.prp.2021.153340
Source: Pathology, Research and Practice - February 7, 2021 Category: Pathology Authors: Jun Zhang Tao Zhang Bensen Tang Jing Li Zhengang Zha Source Type: research

Astragalus improve aging bone marrow mesenchymal stem cells (BMSCs) vitality and osteogenesis through VD-FGF23-Klotho axis.
This study confirmed that astragalus could inhibit the aging of BMSCs and improve the osteogenesis ability by regulating the VD-FGF23-Klotho pathway. This study provided a certain research basis for the therapeutic of traditional Chinese medicine (TCM) on primary osteoporosis. PMID: 32355520 [PubMed]
Source: International Journal of Clinical and Experimental Pathology - May 3, 2020 Category: Pathology Authors: Pu X, Chai Y, Guan L, Li W, Gao J, Jiang Z, Li Q, Wu Y, Chen Y Tags: Int J Clin Exp Pathol Source Type: research