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SOCS and Herpesviruses, With Emphasis on Cytomegalovirus Retinitis
Christine I. Alston1,2 and Richard D. Dix1,2* 1Department of Biology, Viral Immunology Center, Georgia State University, Atlanta, GA, United States 2Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, United States Suppressor of cytokine signaling (SOCS) proteins provide selective negative feedback to prevent pathogeneses caused by overstimulation of the immune system. Of the eight known SOCS proteins, SOCS1 and SOCS3 are the best studied, and systemic deletion of either gene causes early lethality in mice. Many viruses, including herpesviruses such as herpes simplex virus and cytomega...
Source: Frontiers in Immunology - April 10, 2019 Category: Allergy & Immunology Source Type: research

Increased expression of TLR2 in CD4(+) T cells from SLE patients enhances immune reactivity and promotes IL-17 expression through histone modifications.
This article is protected by copyright. All rights reserved. PMID: 26079624 [PubMed - as supplied by publisher]
Source: European Journal of Immunology - June 15, 2015 Category: Allergy & Immunology Authors: Liu Y, Liao J, Zhao M, Wu H, Yung S, Chan TM, Akihiko Y, Lu Q Tags: Eur J Immunol Source Type: research

Increased expression of TLR2 in CD4+ T cells from SLE patients enhances immune reactivity and promotes IL‐17 expression through histone modifications
This article is protected by copyright. All rights reserved
Source: European Journal of Immunology - June 1, 2015 Category: Allergy & Immunology Authors: Yu Liu, Jieyue Liao, Ming Zhao, Haijing Wu, Susan Yung, Tak Mao Chan, Yoshimura Akihiko, Qianjin Lu Tags: Regular Article Source Type: research