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Source: BMJ Open

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Total 1631 results found since Jan 2013.

Analysis and comparison of clinical practice guidelines regarding treatment recommendations for chronic tinnitus in adults: a systematic review
Conclusions There were notable differences with respect to whether guidelines considered the available evidence sufficient enough to make a recommendation. Notably, we identified substantial differences in the rigour of guideline design and development. Reporting was poor in many guidelines. Future guidelines could benefit from the use of reporting tools to improve reporting and transparency and the inclusion of guideline experts and patients to improve the quality of clinical practice guidelines on tinnitus.
Source: BMJ Open - September 15, 2023 Category: General Medicine Authors: Meijers, S., Stegeman, I., van der Leun, J. A., Assegaf, S. A., Smit, A. L. Tags: Open access, Ear, nose and throat/otolaryngology Source Type: research

Efficacy and safety of drug therapy for the prevention and treatment of chemotherapy-induced peripheral neuropathy: a protocol for a systematic review and network meta-analysis
This article describes a protocol for evaluating the efficacy and safety of drug therapy for the prevention and treatment of CIPN. The results of the proposed systematic review with network meta-analysis (NMA) will provide new insights into the prevention and treatment of CIPN. Methods and analysis We will conduct a literature search in MEDLINE, PubMed, Embase, Cochrane Central Register of Controlled Trials and ClinicalTrials.gov to find relevant articles published through January 2023. We will include studies that investigated the efficacy and safety of vitamin B12, goshajinkigan, non-steroidal anti-inflammatory analgesi...
Source: BMJ Open - September 12, 2023 Category: General Medicine Authors: Sato, M. T., Hasegawa, T., Noma, H., Sugita, H., Ota, E. Tags: Open access, Oncology Source Type: research

Facilitators of and barriers to patient and public involvement in building learning health systems in community health services settings: a scoping review protocol
Introduction The development of learning health systems (LHSs) has often focused on optimally leveraging data. More attention should be paid to patient and public involvement or community engagement in forming learning communities that work together to build LHS. This scoping review aims to identify facilitators of and barriers to involving patients and the public in building LHSs in community health services settings. Methods and analysis We will use the Joanna Briggs Institute’s scoping review methodology. We will review literature in English published from 1 January 2007 to 31 December 2022. The databases that wi...
Source: BMJ Open - September 12, 2023 Category: General Medicine Authors: Hung, L., Wong, K. L. Y., Chan, I., Vasarhelyi, K. Tags: Open access, Public health Source Type: research

Cannabis and cannabinoids in dermatology: protocol for a systematic review and meta-analysis of quantitative outcomes
This study does not require ethical approval because no original data will be collected. The findings will be presented at conferences and published in peer-reviewed journals. PROSPERO registration number CRD42023397189.
Source: BMJ Open - September 12, 2023 Category: General Medicine Authors: Sermsaksasithorn, P., Nopsopon, T., Samuthpongtorn, C., Chotirosniramit, K., Pongpirul, K. Tags: Open access, Dermatology Source Type: research

Machine learning models for predicting pre-eclampsia: a systematic review protocol
Introduction Pre-eclampsia is one of the most serious clinical problems of pregnancy that contribute significantly to maternal mortality worldwide. This systematic review aims to identify and summarise the predictive factors of pre-eclampsia using machine learning models and evaluate the diagnostic accuracy of machine learning models in predicting pre-eclampsia. Methods and analysis This review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. This search strategy includes the search for published studies from inception to January 2023. Databases include the Cochrane Central Reg...
Source: BMJ Open - September 11, 2023 Category: General Medicine Authors: Ranjbar, A., Taeidi, E., Mehrnoush, V., Roozbeh, N., Darsareh, F. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research

Interventions to reduce wait times for adolescents seeking mental health services: a scoping review protocol
Introduction The demand for adolescent mental health services has increased significantly in recent years, leading to excessive wait times for adolescents seeking mental health services and poor mental health outcomes. Timely access to mental health services is critical to reducing the risk of symptom chronicity and progression to mental disorder. A better understanding of whether and how interventions to reduce wait times impact mental health outcomes is needed to guide mental health policymakers and service planners in their approach to reducing wait times. Methods and analysis The scoping review will use Arksey and O'M...
Source: BMJ Open - September 7, 2023 Category: General Medicine Authors: McLaughlin, S., Staniland, L., Egan, S. J., Wheadon, J., Munro, C., Preece, D., Furlong, Y., Mavaddat, N., Thompson, A., Robinson, S., Chen, W., Myers, B. Tags: Open access, Mental health Source Type: research

Prognostic factors associated with failure of total elbow replacement: a protocol for a systematic review
Introduction Total elbow replacement (TER) has higher failure rates requiring revision surgery compared with the replacement of other joints. Understanding the factors associated with failure is essential for informed decision-making between patients and clinicians, and for reducing the failure rate. This review aims to identify, describe and appraise the literature examining prognostic factors for failure of TER. Methods and analysis This systematic review will be conducted and reported in line with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. Electronic literature searches ...
Source: BMJ Open - August 30, 2023 Category: General Medicine Authors: Hamoodi, Z., Gehringer, C. K., Bull, L. M., Hughes, T., Kearsley-Fleet, L., Sergeant, J. C., Watts, A. C. Tags: Open access, Surgery Source Type: research

Effect modification in network meta-analyses for relapsed/refractory multiple myeloma: systematic review and meta-analysis
Conclusions Based on the available evidence, effect modification appears to be sufficiently small that it can be neglected in adequately performed NMAs. NMAs can probably be relied on to provide estimates of HRs for OS and PFS in RRMM, subject to caveats discussed herein.
Source: BMJ Open - August 29, 2023 Category: General Medicine Authors: Rose, C. J., Ohm, I. K., Giske, L., Naess, G. E., Fretheim, A. Tags: Open access, Oncology Source Type: research

Improving primary care referral to specialist services: a protocol for a 10-year global systematic review in the Australian context
This study does not require ethics committee review as it solely focuses on analysing published literature. Findings will be published and disseminated through a peer-reviewed journal. PROSPERO registration number CRD42022354890.
Source: BMJ Open - August 29, 2023 Category: General Medicine Authors: Ekanayake, S. K. D. M., Ward, A. E., Heart, D., Valery, P., Soar, J. Tags: Open access, Public health Source Type: research

Stigma of dementia during the COVID-19 pandemic: a scoping review protocol
Introduction Dementia-related stigma reduces the quality of life of people living with dementia and their care partners. However, there is a dearth of literature synthesising knowledge on stigma of dementia during the COVID-19 pandemic. This scoping review protocol outlines a methodology that will be used to understand the impact of stigma on people living with dementia during the pandemic. Addressing dementia-related stigma is critical to promoting timely dementia diagnoses and enhancing the quality of life for people living with dementia and their care partners. Methods and analysis This review will follow the Arksey an...
Source: BMJ Open - August 29, 2023 Category: General Medicine Authors: Bacsu, J.-D. R., Rahemi, Z., Nanson, K., Webster, C., Norman, M., Spiteri, R. J. Tags: Open access, Geriatric medicine, COVID-19 Source Type: research

Scoping review on Physical Health Conditions in Irish Travellers (Minceiri)
Conclusions Overall, Irish Travellers experience a disproportionate burden of physical health conditions compared with background populations. Healthcare providers need to be aware of the unique physical health burden experienced by many Irish Travellers. Multifaceted strategies are needed to improve the health profile of this vulnerable and marginalised group.
Source: BMJ Open - August 28, 2023 Category: General Medicine Authors: Kennedy, F., Ward, A., Mockler, D., Villani, J., Broderick, J. Tags: Open access, Public health Source Type: research

Impact of adapting paediatric intensive care units for adult care during the COVID-19 pandemic: a scoping review
Conclusion COVID-19 has strained institutional resources across the globe. To relieve the burden on intensive care units (ICUs), some PICUs adjusted their units to care for critically ill adults, with other PICUs making significant changes, including the redeployment of staff to adult ICUs to provide extra care for adults. Overall, PICUs were collectively well equipped to care for adult patients, with care enhanced by implementing elements of holistic, family-centred PICU practices. The pandemic fostered a collaborative approach among PICU teams and wider hospital communities. However, specific healthcare guidelines had to...
Source: BMJ Open - August 28, 2023 Category: General Medicine Authors: Hill, K., McCabe, C., Brenner, M. Tags: Open access, Paediatrics, COVID-19 Source Type: research

Supportive care needs of patients who had a stroke: a scoping review protocol
Introduction Incidences of stroke are on the rise and approximately 80 million stroke survivors worldwide live with disabilities. Supportive care needs of stroke survivors are not adequately defined, and the assessment tools to help care service providers identify these needs are unclear. The overall aim of this scoping review will be to map the supportive care needs of stroke survivors against the Supportive Care Needs Framework. Methods and analysis This scoping review will be conducted following Arksey and O’Malley’s methodological framework and Joanna Briggs Institute (JBI) updated methodological guidance ...
Source: BMJ Open - August 24, 2023 Category: General Medicine Authors: Zhang, H., Xu, K., Ma, J. Y., Zhang, X. Y., Sun, Y. Y., Xiao, L. D., Yan, F., Luo, Y. Y., Tang, S. Tags: Open access, Health services research Source Type: research

Admission plasma potassium and length of hospital stay: a meta-analysis
Conclusion Hospital length of stay follows a U-shaped distribution, with duration of admission being twofold greater at the extremes of the potassium range.
Source: BMJ Open - August 24, 2023 Category: General Medicine Authors: Logan Ellis, H., Llewellyn, D., Mendis, J., Whyte, M. Tags: Open access, Diabetes and Endocrinology Source Type: research

Psychosocial interventions for the prevention of self-harm repetition: protocol for a systematic review and network meta-analysis
Introduction Suicide is an important public health problem. Providing evidence-based psychosocial interventions to individuals presenting with self-harm is recognised as an important suicide prevention strategy. Therefore, it is crucial to understand which intervention is most effective in preventing self-harm repetition. We will evaluate the comparative efficacy of psychosocial interventions for the prevention of self-harm in adults. Methods and analysis We will perform a systematic review and network meta-analysis (NMA) of randomised controlled trials (RCTs) testing psychosocial interventions for the prevention of self-...
Source: BMJ Open - August 24, 2023 Category: General Medicine Authors: Orri, M., Gifuni, A. J., Ougrin, D., Boruff, J., Cipriani, A., Furukawa, T. A., Schaffer, D., Del Giovane, C., Inja, A., Turecki, G., Geoffroy, M.-C., Cortese, S. Tags: Open access, Mental health Source Type: research