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Infectious Disease: Fungal Infections

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Total 23 results found since Jan 2013.

Successful use of subcutaneous anakinra in hemophagocytic lymphohistiocytosis precipitated by candidiasis in a patient with systemic lupus erythematosus: A case report and description of a novel therapeutic regimen
We describe a case of HLH precipitated by fungal infection which occurred as a consequenc e of immunosuppression for management of systemic lupus erythematosus (SLE) and necrotizing myopathy. The patient presented with immune-mediated disease of the muscles and lung which was treated with high-dose corticosteroids and aggressive immunosuppression. HLH emerged in the context of confirmed candidiasis and features of severe sepsis. The patient responded rapidly to antifungal therapy and high-dose anakinra, which was administered subcutaneously and progressively weaned over 4 weeks. She completed HLH treatment as an outpatie...
Source: International Journal of Rheumatic Diseases - May 8, 2023 Category: Rheumatology Authors: Gary Xu, Sadia Tasnim Islam, Lydia Makarie ‐Rofail, Les Barnsley, Sandhya Limaye Tags: CASE REPORT Source Type: research

Angioinvasive gastrointestinal mucormycosis with duodenal necrosis and perforation in a patient with visceral myopathy
Z Gastroenterol. 2023 Apr 12. doi: 10.1055/a-2053-9149. Online ahead of print.ABSTRACTA 55-year-old woman with a past medical history of visceral myopathy with multiple resultant abdominal surgeries, colectomy caused by severe pseudo-obstruction, and end-stage renal disease on hemodialysis presented with complaints of nausea, abdominal distention, vomiting, and diarrhea for five days. Small-bowel obstruction was identified on CT. She subsequently developed acute gastrointestinal bleeding, anemia, and hemodynamic instability. Extensive gastric ulceration with frank hemorrhage prompted urgent subtotal gastrectomy with multip...
Source: Zeitschrift fur Gastroenterologie - April 12, 2023 Category: Gastroenterology Authors: Nicole Hunter Alexander Kusnik Layla Hatem Ari Chodos Anthony Baratta Prasad Penmetsa Yana Levin Source Type: research