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Therapy: Immunotherapy

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Total 743 results found since Jan 2013.

Epitope Mapping of an Anti-Chinese/Golden Hamster Podoplanin Monoclonal Antibody
In this study, we examined the critical epitope of 281-mG2a-f, using enzyme-linked immunosorbent assay (ELISA) with synthesized peptides. First, we performed ELISA with peptides derived from ChamPDPN and GhamPDPN extracellular domain, and found that 281-mG2a-f reacted with the peptides, which commonly possess the KIPFEELxT sequence. Next, we analyzed the reaction with the alanine-substituted mutants, and revealed that 281-mG2a-f did not recognize the alanine-substituted peptides of I75A, F77A, and E79A of ChamPDPN. Furthermore, these peptides could not inhibit the recognition of 281-mG2a-f to ChamPDPN-expressing cells by f...
Source: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy - June 6, 2022 Category: Microbiology Authors: Nohara Goto Hiroyuki Suzuki Tomohiro Tanaka Teizo Asano Mika K Kaneko Yukinari Kato Source Type: research

Viruses, Vol. 14, Pages 1166: & gamma; & delta; T Cells in Emerging Viral Infection: An Overview
Viruses, Vol. 14, Pages 1166: γδ T Cells in Emerging Viral Infection: An Overview Viruses doi: 10.3390/v14061166 Authors: Eleonora Cimini Chiara Agrati New emerging viruses belonging to the Coronaviridae, Flaviviridae, and Filoviridae families are serious threats to public health and represent a global concern. The surveillance to monitor the emergence of new viruses and their transmission is an important target for public health authorities. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an excellent example of a pathogen able to cause a pandemic. In a few months, SARS-CoV-2 ...
Source: Viruses - May 27, 2022 Category: Virology Authors: Eleonora Cimini Chiara Agrati Tags: Review Source Type: research

BCG Vaccination: A potential tool against COVID-19 and COVID-19-like Black Swan incidents
Int Immunopharmacol. 2022 May 17;108:108870. doi: 10.1016/j.intimp.2022.108870. Online ahead of print.ABSTRACTThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19), and its variants have brought unprecedented impacts to the global public health system, politics, economy, and other fields. Although more than ten COVID-19 specific vaccines have been approved for emergency use, COVID-19 prevention and control still face many challenges. Bacille Calmette-Guérin (BCG) is the only authorized vaccine used to fight against tuberculosis (TB), it has been hy...
Source: International Immunopharmacology - May 21, 2022 Category: Allergy & Immunology Authors: Wenping Gong Yingqing Mao Yuexi Li Yong Qi Source Type: research