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Specialty: Gastroenterology
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Total 4295 results found since Jan 2013.
Interferon-lambda: New role in intestinal symptoms of COVID-19
World J Gastroenterol. 2023 Apr 7;29(13):1942-1954. doi: 10.3748/wjg.v29.i13.1942.ABSTRACTThe tremendous public health and economic impact of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a huge challenge globally. There is increasing evidence that SARS-CoV-2 induces intestinal infections. Type III interferon (IFN-λ) has an antiviral role in intestinal infection, with focused, long-lasting, and non-inflammatory characteristics. This review presents a summary of the structure of SARS-CoV-2, including its invasion and immune escape mechanisms. Emphasi...
Source: World Journal of Gastroenterology - May 8, 2023 Category: Gastroenterology Authors: Yi-Yang Pan Liu-Can Wang Feng Yang Min Yu Source Type: research
Segmental Colitis Associated with Diverticulosis (SCAD)
AbstractPurpose of ReviewA distinctive, possibly “novel” form of a segmental inflammatory colonic disease process associated with diverticular disease (so-called SCAD or segmental-colitis-associated-diverticulosis) is reviewed.Recent FindingsAlthough this phenotype of inflammatory colonic disease was initially recognized decades ago, mainly in the elderly, recent evidence from long term natural history studies along with meta-analyses confirms that its clinical course is usually benign and drug-responsive. Interestingly, its appearance in some treated with monoclonal agents (eg., ipilimumab associated colitis) or infec...
Source: Current Gastroenterology Reports - May 2, 2023 Category: Gastroenterology Source Type: research
Mechanisms of gastrointestinal barrier dysfunction in COVID-19 patients
World J Gastroenterol. 2023 Apr 21;29(15):2283-2293. doi: 10.3748/wjg.v29.i15.2283.ABSTRACTCoronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major global public health event, resulting in a significant social and economic burden. Although COVID-19 was initially characterized as an upper respiratory and pulmonary infection, recent evidence suggests that it is a complex disease including gastrointestinal symptoms, such as diarrhea, nausea, and vomiting. Moreover, it remains unclear whether the gastrointestinal symptoms are caused by direct infect...
Source: World Journal of Gastroenterology : WJG - May 1, 2023 Category: Gastroenterology Authors: Weijie Xue Masaki Honda Taizo Hibi Source Type: research
COVID-19 related biliary injury: A review of recent literature
World J Gastroenterol. 2023 Apr 14;29(14):2127-2133. doi: 10.3748/wjg.v29.i14.2127.ABSTRACTSince its emergence in 2019, it has become apparent that coronavirus 2019 (COVID-19) infection can result in multi systemic involvement. In addition to pulmonary symptoms, hepatobiliary involvement has been widely reported. Extent of hepatic involvement ranges from minor elevation in liver function tests (LFTs) to significant hepatocellular or cholestatic injury. In majority of cases, resolution of hepatic injury or improvement in LFTs is noted as patients recover from COVID-19 infection. However, severe biliary tract injury progress...
Source: World Journal of Gastroenterology : WJG - May 1, 2023 Category: Gastroenterology Authors: Sujani Yadlapati Simone A Jarrett Daniel Baik Adib Chaaya Source Type: research
Insight into the liver dysfunction in COVID-19 patients: Molecular mechanisms and possible therapeutic strategies
World J Gastroenterol. 2023 Apr 14;29(14):2064-2077. doi: 10.3748/wjg.v29.i14.2064.ABSTRACTAs of June 2022, more than 530 million people worldwide have become ill with coronavirus disease 2019 (COVID-19). Although COVID-19 is most commonly associated with respiratory distress (severe acute respiratory syndrome), meta-analysis have indicated that liver dysfunction also occurs in patients with severe symptoms. Current studies revealed distinctive patterning in the receptors on the hepatic cells that helps in viral invasion through the expression of angiotensin-converting enzyme receptors. It has also been reported that in so...
Source: World Journal of Gastroenterology : WJG - May 1, 2023 Category: Gastroenterology Authors: Naina Khullar Jasvinder Singh Bhatti Satwinder Singh Bhawana Thukral P Hemachandra Reddy Gurjit Kaur Bhatti Source Type: research
Mechanisms of gastrointestinal barrier dysfunction in COVID-19 patients
World J Gastroenterol. 2023 Apr 21;29(15):2283-2293. doi: 10.3748/wjg.v29.i15.2283.ABSTRACTCoronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major global public health event, resulting in a significant social and economic burden. Although COVID-19 was initially characterized as an upper respiratory and pulmonary infection, recent evidence suggests that it is a complex disease including gastrointestinal symptoms, such as diarrhea, nausea, and vomiting. Moreover, it remains unclear whether the gastrointestinal symptoms are caused by direct infect...
Source: World Journal of Gastroenterology - May 1, 2023 Category: Gastroenterology Authors: Weijie Xue Masaki Honda Taizo Hibi Source Type: research
COVID-19 related biliary injury: A review of recent literature
World J Gastroenterol. 2023 Apr 14;29(14):2127-2133. doi: 10.3748/wjg.v29.i14.2127.ABSTRACTSince its emergence in 2019, it has become apparent that coronavirus 2019 (COVID-19) infection can result in multi systemic involvement. In addition to pulmonary symptoms, hepatobiliary involvement has been widely reported. Extent of hepatic involvement ranges from minor elevation in liver function tests (LFTs) to significant hepatocellular or cholestatic injury. In majority of cases, resolution of hepatic injury or improvement in LFTs is noted as patients recover from COVID-19 infection. However, severe biliary tract injury progress...
Source: World Journal of Gastroenterology - May 1, 2023 Category: Gastroenterology Authors: Sujani Yadlapati Simone A Jarrett Daniel Baik Adib Chaaya Source Type: research
Insight into the liver dysfunction in COVID-19 patients: Molecular mechanisms and possible therapeutic strategies
World J Gastroenterol. 2023 Apr 14;29(14):2064-2077. doi: 10.3748/wjg.v29.i14.2064.ABSTRACTAs of June 2022, more than 530 million people worldwide have become ill with coronavirus disease 2019 (COVID-19). Although COVID-19 is most commonly associated with respiratory distress (severe acute respiratory syndrome), meta-analysis have indicated that liver dysfunction also occurs in patients with severe symptoms. Current studies revealed distinctive patterning in the receptors on the hepatic cells that helps in viral invasion through the expression of angiotensin-converting enzyme receptors. It has also been reported that in so...
Source: World Journal of Gastroenterology - May 1, 2023 Category: Gastroenterology Authors: Naina Khullar Jasvinder Singh Bhatti Satwinder Singh Bhawana Thukral P Hemachandra Reddy Gurjit Kaur Bhatti Source Type: research
Mechanisms of gastrointestinal barrier dysfunction in COVID-19 patients
World J Gastroenterol. 2023 Apr 21;29(15):2283-2293. doi: 10.3748/wjg.v29.i15.2283.ABSTRACTCoronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major global public health event, resulting in a significant social and economic burden. Although COVID-19 was initially characterized as an upper respiratory and pulmonary infection, recent evidence suggests that it is a complex disease including gastrointestinal symptoms, such as diarrhea, nausea, and vomiting. Moreover, it remains unclear whether the gastrointestinal symptoms are caused by direct infect...
Source: World Journal of Gastroenterology : WJG - May 1, 2023 Category: Gastroenterology Authors: Weijie Xue Masaki Honda Taizo Hibi Source Type: research
COVID-19 related biliary injury: A review of recent literature
World J Gastroenterol. 2023 Apr 14;29(14):2127-2133. doi: 10.3748/wjg.v29.i14.2127.ABSTRACTSince its emergence in 2019, it has become apparent that coronavirus 2019 (COVID-19) infection can result in multi systemic involvement. In addition to pulmonary symptoms, hepatobiliary involvement has been widely reported. Extent of hepatic involvement ranges from minor elevation in liver function tests (LFTs) to significant hepatocellular or cholestatic injury. In majority of cases, resolution of hepatic injury or improvement in LFTs is noted as patients recover from COVID-19 infection. However, severe biliary tract injury progress...
Source: World Journal of Gastroenterology : WJG - May 1, 2023 Category: Gastroenterology Authors: Sujani Yadlapati Simone A Jarrett Daniel Baik Adib Chaaya Source Type: research
Insight into the liver dysfunction in COVID-19 patients: Molecular mechanisms and possible therapeutic strategies
World J Gastroenterol. 2023 Apr 14;29(14):2064-2077. doi: 10.3748/wjg.v29.i14.2064.ABSTRACTAs of June 2022, more than 530 million people worldwide have become ill with coronavirus disease 2019 (COVID-19). Although COVID-19 is most commonly associated with respiratory distress (severe acute respiratory syndrome), meta-analysis have indicated that liver dysfunction also occurs in patients with severe symptoms. Current studies revealed distinctive patterning in the receptors on the hepatic cells that helps in viral invasion through the expression of angiotensin-converting enzyme receptors. It has also been reported that in so...
Source: World Journal of Gastroenterology : WJG - May 1, 2023 Category: Gastroenterology Authors: Naina Khullar Jasvinder Singh Bhatti Satwinder Singh Bhawana Thukral P Hemachandra Reddy Gurjit Kaur Bhatti Source Type: research
