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Specialty: Gastroenterology

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Total 4295 results found since Jan 2013.

COVID-19 and liver injury: Pathophysiology, risk factors, outcome and management in special populations
World J Hepatol. 2023 Apr 27;15(4):441-459. doi: 10.4254/wjh.v15.i4.441.ABSTRACTThe coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 is an ongoing health concern. In addition to affecting the respiratory system, COVID-19 can potentially damage other systems in the body, leading to extra-pulmonary manifestations. Hepatic manifestations are among the common consequences of COVID-19. Although the precise mechanism of liver injury is still questionable, several mechanisms have been hypothesized, including direct viral effect, cytokine storm, hypoxic-ischemic injury, hypoxia-reperfus...
Source: World Journal of Hepatology - May 19, 2023 Category: Gastroenterology Authors: Romina Roshanshad Amirhossein Roshanshad Reza Fereidooni Mahnaz Hosseini-Bensenjan Source Type: research

Inferior outcomes of liver transplantation for hepatocellular carcinoma during early-COVID-19 pandemic in the United States
CONCLUSION: During COVID period, there was a significant decrease in LTs performed for HCC. While early postoperative outcomes of LT for HCC were same, the overall and graft survival of LTs for HCC after 180 days were significantly inferior.PMID:37206654 | PMC:PMC10190691 | DOI:10.4254/wjh.v15.i4.554
Source: World Journal of Hepatology - May 19, 2023 Category: Gastroenterology Authors: Inkyu S Lee Kenji Okumura Ryosuke Misawa Hiroshi Sogawa Gregory Veillette Devon John Thomas Diflo Seigo Nishida Abhay Dhand Source Type: research

Obesity and Viral Infections
The 2019 novel coronavirus disease (COVID-19) triggered a rapidly expanding global pandemic. The presence of obesity in patients with COVID-19 has been established as a risk factor for disease severity, hospital admission, and mortality. Thus, it is imperative those living with obesity be vaccinated against COVID-19. Although there is a timeframe COVID-19 vaccines are efficacious in those living with obesity, more studies need to be conducted to ensure that those long-lasting protection is maintained, as obesity has implications on the immune system.
Source: Gastroenterology Clinics of North America - May 16, 2023 Category: Gastroenterology Authors: Priya Jaisinghani, Rekha Kumar Source Type: research

SARS-CoV-2 induced liver injury: Incidence, risk factors, impact on COVID-19 severity and prognosis in different population groups
World J Gastroenterol. 2023 Apr 28;29(16):2397-2432. doi: 10.3748/wjg.v29.i16.2397.ABSTRACTLiver is unlikely the key organ driving mortality in coronavirus disease 2019 (COVID-19) however, liver function tests (LFTs) abnormalities are widely observed mostly in moderate and severe cases. According to this review, the overall prevalence of abnormal LFTs in COVID-19 patients ranges from 2.5% to 96.8% worldwide. The geographical variability in the prevalence of underlying diseases is the determinant for the observed discrepancies between East and West. Multifactorial mechanisms are implicated in COVID-19-induced liver injury. ...
Source: World Journal of Gastroenterology - May 14, 2023 Category: Gastroenterology Authors: George D Liatsos Source Type: research

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