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Dissemination of IncI plasmid encoding < em > bla < /em > < sub > CTX-M-1 < /sub > is not hampered by its fitness cost in the pig's gut
Antimicrob Agents Chemother. 2023 Sep 13:e0011123. doi: 10.1128/aac.00111-23. Online ahead of print.ABSTRACTMultiresistance plasmids belonging to the IncI incompatibility group have become one of the most pervasive plasmid types in extended-spectrum beta-lactamase-producing Escherichia coli of animal origin. The extent of the burden imposed on the bacterial cell by these plasmids seems to modulate the emergence of "epidemic" plasmids. However, in vivo data in the natural environment of the strains are scarce. Here, we investigated the cost of a blaCTX-M-1-IncI1 epidemic plasmid in a commensal E. coli animal strain, UB12-RC...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Margaux Allain Anne Claire Mah érault Benoit Gachet Caroline Martinez B énédicte Condamine M élanie Magnan Isabelle Kempf Erick Denamur Luce Landraud Source Type: research

Effectiveness of cefmetazole versus meropenem for invasive urinary tract infections caused by extended-spectrum β-lactamase-producing < em > Escherichia coli < /em >
Antimicrob Agents Chemother. 2023 Sep 13:e0051023. doi: 10.1128/aac.00510-23. Online ahead of print.ABSTRACTCefmetazole is active against extended-spectrum β-lactamase-producing Escherichia coli (ESBLEC) and is a potential candidate for carbapenem-sparing therapy. This multicenter, observational study included patients hospitalized for invasive urinary tract infection due to ESBLEC between March 2020 and November 2021 at 10 facilities in Japan, for whom either cefmetazole or meropenem was initiated as a definitive therapy within 96 h of culture collection and continued for at least 3 d. Outcomes included clinical and micr...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Kayoko Hayakawa Yasufumi Matsumura Kohei Uemura Shinya Tsuzuki Aki Sakurai Ryutaro Tanizaki Koh Shinohara Takehiro Hashimoto Ryota Hase Takashi Matono Hideaki Kato Momoko Mawatari Hiroshi Hara Yukihiro Hamada Sho Saito Norio Ohmagari Yohei Doi Source Type: research

Dissemination of IncI plasmid encoding < em > bla < /em > < sub > CTX-M-1 < /sub > is not hampered by its fitness cost in the pig's gut
Antimicrob Agents Chemother. 2023 Sep 13:e0011123. doi: 10.1128/aac.00111-23. Online ahead of print.ABSTRACTMultiresistance plasmids belonging to the IncI incompatibility group have become one of the most pervasive plasmid types in extended-spectrum beta-lactamase-producing Escherichia coli of animal origin. The extent of the burden imposed on the bacterial cell by these plasmids seems to modulate the emergence of "epidemic" plasmids. However, in vivo data in the natural environment of the strains are scarce. Here, we investigated the cost of a blaCTX-M-1-IncI1 epidemic plasmid in a commensal E. coli animal strain, UB12-RC...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Margaux Allain Anne Claire Mah érault Benoit Gachet Caroline Martinez B énédicte Condamine M élanie Magnan Isabelle Kempf Erick Denamur Luce Landraud Source Type: research

Effectiveness of cefmetazole versus meropenem for invasive urinary tract infections caused by extended-spectrum β-lactamase-producing < em > Escherichia coli < /em >
Antimicrob Agents Chemother. 2023 Sep 13:e0051023. doi: 10.1128/aac.00510-23. Online ahead of print.ABSTRACTCefmetazole is active against extended-spectrum β-lactamase-producing Escherichia coli (ESBLEC) and is a potential candidate for carbapenem-sparing therapy. This multicenter, observational study included patients hospitalized for invasive urinary tract infection due to ESBLEC between March 2020 and November 2021 at 10 facilities in Japan, for whom either cefmetazole or meropenem was initiated as a definitive therapy within 96 h of culture collection and continued for at least 3 d. Outcomes included clinical and micr...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Kayoko Hayakawa Yasufumi Matsumura Kohei Uemura Shinya Tsuzuki Aki Sakurai Ryutaro Tanizaki Koh Shinohara Takehiro Hashimoto Ryota Hase Takashi Matono Hideaki Kato Momoko Mawatari Hiroshi Hara Yukihiro Hamada Sho Saito Norio Ohmagari Yohei Doi Source Type: research

Assessment of chemical compositions and antibacterial activity of the essential oil of < em > Mentha piperita < /em > in response to salicylic acid
Nat Prod Res. 2023 Sep 13:1-12. doi: 10.1080/14786419.2023.2256020. Online ahead of print.ABSTRACTMentha piperita, as a species of the mint family, is used in various medical, cosmetic, industrial and culinary products. The effect of different concentrations of salicylic acid (SA) (0. 0.5, 1 mM) on phytochemical activity and antimicrobial potential of Mentha piperita essential oil against six human pathogenic bacteria (Streptococcus agalactiae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus and Listeria monocytogenes) were investigated. According to the results to prevent the growth ...
Source: Natural Product Research - September 13, 2023 Category: Biochemistry Authors: Soheila Afkar Source Type: research

Analytical studies on the conjugation site specificity of trastuzumab modified by Escherichia coli lipoate ligase A: multiple-enzyme digestion approach for peptide mapping
This study not only contributes to the understanding of peptide modification, but also presents an improved methodology that promises to stimulate further research in this field.PMID:37702772 | DOI:10.1007/s00216-023-04922-1
Source: Analytical and Bioanalytical Chemistry - September 13, 2023 Category: Chemistry Authors: Natsuki Shikida Shunsuke Yamazaki Kazutoshi Takahashi Yutaka Matsuda Kazutaka Shimbo Source Type: research

Evaluation of the QIAstat-Dx Meningitis/Encephalitis Panel, a multiplex PCR platform for the detection of community-acquired meningoencephalitis
J Clin Microbiol. 2023 Sep 13:e0042623. doi: 10.1128/jcm.00426-23. Online ahead of print.ABSTRACTRapid identification of the causative pathogens of central nervous system infections is essential for providing appropriate management and improving patient outcomes. The performance of QIAstat-Dx Meningitis/Encephalitis (ME) Panel-a multiplex PCR testing platform-in detecting pathogens implicated in meningitis and/or encephalitis was evaluated using BioFire FilmArray ME Panel as a comparator method. This multicenter study analyzed 585 retrospective residual cerebrospinal fluid specimens and 367 contrived specimens. The QIAstat...
Source: Herpes - September 13, 2023 Category: Infectious Diseases Authors: Thomas Sundelin Johanna Bialas Juana de Diego Markus Hermanowski Hendrik Leibhan L éa Ponderand Marti Juanola-Falgarona Tara Jones Melisa Rey Sarah Johnson Josep Pareja Yvan Caspar Source Type: research

Dissemination of IncI plasmid encoding < em > bla < /em > < sub > CTX-M-1 < /sub > is not hampered by its fitness cost in the pig's gut
Antimicrob Agents Chemother. 2023 Sep 13:e0011123. doi: 10.1128/aac.00111-23. Online ahead of print.ABSTRACTMultiresistance plasmids belonging to the IncI incompatibility group have become one of the most pervasive plasmid types in extended-spectrum beta-lactamase-producing Escherichia coli of animal origin. The extent of the burden imposed on the bacterial cell by these plasmids seems to modulate the emergence of "epidemic" plasmids. However, in vivo data in the natural environment of the strains are scarce. Here, we investigated the cost of a blaCTX-M-1-IncI1 epidemic plasmid in a commensal E. coli animal strain, UB12-RC...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Margaux Allain Anne Claire Mah érault Benoit Gachet Caroline Martinez B énédicte Condamine M élanie Magnan Isabelle Kempf Erick Denamur Luce Landraud Source Type: research

Effectiveness of cefmetazole versus meropenem for invasive urinary tract infections caused by extended-spectrum β-lactamase-producing < em > Escherichia coli < /em >
Antimicrob Agents Chemother. 2023 Sep 13:e0051023. doi: 10.1128/aac.00510-23. Online ahead of print.ABSTRACTCefmetazole is active against extended-spectrum β-lactamase-producing Escherichia coli (ESBLEC) and is a potential candidate for carbapenem-sparing therapy. This multicenter, observational study included patients hospitalized for invasive urinary tract infection due to ESBLEC between March 2020 and November 2021 at 10 facilities in Japan, for whom either cefmetazole or meropenem was initiated as a definitive therapy within 96 h of culture collection and continued for at least 3 d. Outcomes included clinical and micr...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Kayoko Hayakawa Yasufumi Matsumura Kohei Uemura Shinya Tsuzuki Aki Sakurai Ryutaro Tanizaki Koh Shinohara Takehiro Hashimoto Ryota Hase Takashi Matono Hideaki Kato Momoko Mawatari Hiroshi Hara Yukihiro Hamada Sho Saito Norio Ohmagari Yohei Doi Source Type: research

Dissemination of IncI plasmid encoding < em > bla < /em > < sub > CTX-M-1 < /sub > is not hampered by its fitness cost in the pig's gut
Antimicrob Agents Chemother. 2023 Sep 13:e0011123. doi: 10.1128/aac.00111-23. Online ahead of print.ABSTRACTMultiresistance plasmids belonging to the IncI incompatibility group have become one of the most pervasive plasmid types in extended-spectrum beta-lactamase-producing Escherichia coli of animal origin. The extent of the burden imposed on the bacterial cell by these plasmids seems to modulate the emergence of "epidemic" plasmids. However, in vivo data in the natural environment of the strains are scarce. Here, we investigated the cost of a blaCTX-M-1-IncI1 epidemic plasmid in a commensal E. coli animal strain, UB12-RC...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Margaux Allain Anne Claire Mah érault Benoit Gachet Caroline Martinez B énédicte Condamine M élanie Magnan Isabelle Kempf Erick Denamur Luce Landraud Source Type: research

Effectiveness of cefmetazole versus meropenem for invasive urinary tract infections caused by extended-spectrum β-lactamase-producing < em > Escherichia coli < /em >
Antimicrob Agents Chemother. 2023 Sep 13:e0051023. doi: 10.1128/aac.00510-23. Online ahead of print.ABSTRACTCefmetazole is active against extended-spectrum β-lactamase-producing Escherichia coli (ESBLEC) and is a potential candidate for carbapenem-sparing therapy. This multicenter, observational study included patients hospitalized for invasive urinary tract infection due to ESBLEC between March 2020 and November 2021 at 10 facilities in Japan, for whom either cefmetazole or meropenem was initiated as a definitive therapy within 96 h of culture collection and continued for at least 3 d. Outcomes included clinical and micr...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Kayoko Hayakawa Yasufumi Matsumura Kohei Uemura Shinya Tsuzuki Aki Sakurai Ryutaro Tanizaki Koh Shinohara Takehiro Hashimoto Ryota Hase Takashi Matono Hideaki Kato Momoko Mawatari Hiroshi Hara Yukihiro Hamada Sho Saito Norio Ohmagari Yohei Doi Source Type: research

Multifunctional composite films based on polyvinyl alcohol, quaternary ammonium salt modified cellulose nanofibers and tannic acid-iron ion coordination complexes for food packaging
Int J Biol Macromol. 2023 Sep 11:126857. doi: 10.1016/j.ijbiomac.2023.126857. Online ahead of print.ABSTRACTThe development of sustainable and well-performing food packaging materials takes on critical significance, whereas it is still challenging. To overcome the shortcomings of polyvinyl alcohol (PVA) as a degradable packaging material, in this work, hydrophobic quaternary ammonium salt (QAS) modified cellulose nanofibers (CNF) and tannic acid‑iron ion coordination complexes (TA-Fe) were adopted for the preparation of functional PVA films. The modified CNF (CNF-QAS) not only improved the mechanical properties and water...
Source: International Journal of Biological Macromolecules - September 13, 2023 Category: Biochemistry Authors: Zhiqiang Li Jiahui Qu Liwei Qian Yan Li Jingtao Liu Xue Yao Sufeng Zhang Nica Valentin Wenqi Song Source Type: research

Two birds, one stone: Enhancement of flame retardancy and antibacterial property of viscose fabric using an aminoazole-based cyclotriphosphazene
In this study, an aminoazole-based cyclotriphosphazene (HATA) was designed and synthesized through nucleophilic substitution between hexachlorocyclotriphosphazene and 3-amino-1,2,4-triazole. The application of a rapid dipping strategy and the use of 10 wt% HATA aqueous solution significantly increased the limiting oxygen index of the viscose fabric from 19.3 % to 28.4 %. In addition, the HATA-treated fabric exhibited self-extinguishing properties in vertical flame testing. The peak heat release rate of HATA-treated fabric, according to pyrolysis combustion flow calorimetry, significantly decreased by over 83 %. The scannin...
Source: International Journal of Biological Macromolecules - September 13, 2023 Category: Biochemistry Authors: Tian-Tian Huang Kai Ning Bin Zhao Source Type: research

Dissemination of IncI plasmid encoding < em > bla < /em > < sub > CTX-M-1 < /sub > is not hampered by its fitness cost in the pig's gut
Antimicrob Agents Chemother. 2023 Sep 13:e0011123. doi: 10.1128/aac.00111-23. Online ahead of print.ABSTRACTMultiresistance plasmids belonging to the IncI incompatibility group have become one of the most pervasive plasmid types in extended-spectrum beta-lactamase-producing Escherichia coli of animal origin. The extent of the burden imposed on the bacterial cell by these plasmids seems to modulate the emergence of "epidemic" plasmids. However, in vivo data in the natural environment of the strains are scarce. Here, we investigated the cost of a blaCTX-M-1-IncI1 epidemic plasmid in a commensal E. coli animal strain, UB12-RC...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Margaux Allain Anne Claire Mah érault Benoit Gachet Caroline Martinez B énédicte Condamine M élanie Magnan Isabelle Kempf Erick Denamur Luce Landraud Source Type: research

Effectiveness of cefmetazole versus meropenem for invasive urinary tract infections caused by extended-spectrum β-lactamase-producing < em > Escherichia coli < /em >
Antimicrob Agents Chemother. 2023 Sep 13:e0051023. doi: 10.1128/aac.00510-23. Online ahead of print.ABSTRACTCefmetazole is active against extended-spectrum β-lactamase-producing Escherichia coli (ESBLEC) and is a potential candidate for carbapenem-sparing therapy. This multicenter, observational study included patients hospitalized for invasive urinary tract infection due to ESBLEC between March 2020 and November 2021 at 10 facilities in Japan, for whom either cefmetazole or meropenem was initiated as a definitive therapy within 96 h of culture collection and continued for at least 3 d. Outcomes included clinical and micr...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Kayoko Hayakawa Yasufumi Matsumura Kohei Uemura Shinya Tsuzuki Aki Sakurai Ryutaro Tanizaki Koh Shinohara Takehiro Hashimoto Ryota Hase Takashi Matono Hideaki Kato Momoko Mawatari Hiroshi Hara Yukihiro Hamada Sho Saito Norio Ohmagari Yohei Doi Source Type: research