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Therapy: Stem Cell Therapy
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Total 1246 results found since Jan 2013.
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
