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Total 1918 results found since Jan 2013.

Guidance on Completing a Written Allergy and Anaphylaxis Emergency Plan
This report offers a comprehensive written plan, with advice on individualizing instructions to suit specific patient circumstances.
Source: PEDIATRICS - February 28, 2017 Category: Pediatrics Authors: Wang, J., Sicherer, S. H., SECTION ON ALLERGY AND IMMUNOLOGY Tags: Allergy/Immunology From the American Academy of Pediatrics Source Type: research

A potential breakthrough for peanut allergy treatment
Peanut allergies are among the most rapidly growing food allergies in the United States. Millions of children are currently living with the condition, with new cases being diagnosed daily. (A recent study shows the number of reported peanut allergies tripled in just over a decade.) And because allergic reactions to peanuts tend to be the most severe—80 to 95 percent of all food allergy deaths are peanut or tree nut related—the trend is a serious cause for concern. But a small pilot study published by the Journal of Allergy and Clinical Immunology, may offer hope for the hundred of thousands of families living with the ...
Source: Thrive, Children's Hospital Boston - November 4, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Food allergies Kids' safety Milk allergies Parenting clinical trial food allergy Dale Umetsu Lynda Schneider peanut allergies Rima Rachid Source Type: news

The high costs of food allergy
Between the near constant worry and strict monitoring of every type of food in the area, parenting a child with food allergy can be nerve-wracking and exhausting. And according to research published by JAMA Pediatrics, it can also be extremely expensive. The data shows pediatric food allergies cost an estimated $24.8 billion each year in the U.S, with a majority of that money coming from lost wages and missed career opportunities of the parents of children with food allergies whose jobs take a back seat to managing their child’s condition. “A child’s food allergy often affects more than just his or her ph...
Source: Thrive, Children's Hospital Boston - December 2, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Diseases & conditions Food allergies Food Allergy Program John Lee Parenting Source Type: news

Six tips for throwing a (food allergy-friendly) kids’ party
As food allergies become more and more common—researchers estimate that up to 15 million Americans now have food allergies—there’s a good chance that you’ll soon find yourself hosting a birthday party where one or more of the guests has some type of allergy or dietary restriction. For parents of children without an allergy, it can be an intimidating prospect. How do I keep track of all the things he’s allergic too? What do I do if she has a reaction? Will I have to administer an EpiPen? Will it hurt her if I do it wrong? And while a bit of nervousness is natural, there’s no reason to panic: Ho...
Source: Thrive, Children's Hospital Boston - June 11, 2014 Category: Pediatrics Authors: Tripp Underwood Tags: All posts empowering your child with food allergy Food Allergy Program Source Type: news

Food Allergy in Infants With Atopic Dermatitis: Limitations of Food-Specific IgE Measurements
CONCLUSIONS: In a large cohort of infants at risk for development of food allergy, sIgE levels were not clinically useful for predicting food allergy development.
Source: PEDIATRICS - December 1, 2015 Category: Pediatrics Authors: Spergel, J. M., Boguniewicz, M., Schneider, L., Hanifin, J. M., Paller, A. S., Eichenfield, L. F. Tags: Allergy/Immunology Article Source Type: research

The role of the gut microbiota in food allergy
Purpose of review: The rise in the prevalence of food allergy over the past decades has focused attention of factors that may impact disease development, most notably the gut microbiota. The gut microbial communities play a crucial role in promoting oral tolerance. Their alteration by such factors as Cesarean section delivery, diet and antibiotics may influence disease development. This review highlights recent progress in our understanding of the role of the gut microbiota in the development of food allergy. Recent findings: Food allergy is associated with alterations in the gut microbiota or dysbiosis early in life that...
Source: Current Opinion in Pediatrics - November 4, 2016 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Talal Chatila Source Type: research

Dietary intervention for preventing food allergy in children
Purpose of review: In the past decade, food allergy has been increasingly recognized as an important public health issue. The role of maternal and infant diet in the development of food allergy has been a major focus of research throughout this period. Recently, research in this area has moved from observational studies to intervention trials, and the findings from these trials have started to influence infant feeding guidelines. In this article, we review recent studies of dietary interventions for preventing food allergy, summarize current knowledge and discuss future research directions. Recent findings: The latest res...
Source: Current Opinion in Pediatrics - November 9, 2017 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by David B. Lewis Source Type: research

The diagnosis and management of antibiotic allergy in children: Systematic review to inform a contemporary approach
Conclusions Our literature review found four (6%) publications that performed DPTs to subjects’ index antibiotic across all participants. No rigorous evidence supports using skin prick, ID or in vitro diagnostic testing; indeed, the testing regimens, extracts and positivity criteria used are inconsistent. We recommend that suspected non-serious antibiotic allergy should be primarily investigated using DPT-based clinical protocols. Data examining their safety, acceptability and diagnostic performance are required.
Source: Archives of Disease in Childhood - May 18, 2015 Category: Pediatrics Authors: Marrs, T., Fox, A. T., Lack, G., du Toit, G. Tags: Immunology (including allergy), Drugs: infectious diseases, Child health, Unwanted effects / adverse reactions, Clinical diagnostic tests, Guidelines Review Source Type: research

Advances in immunoglobulin E mediated antibiotic allergy
Purpose of review The purpose of this review is to identify recent advances in our understanding and management of immunoglobulin E (IgE)-mediated antibiotic allergy. Recent findings Antibiotics remain a leading cause of fatal anaphylaxis reported to the FDA. However, recent advances have defined the features of adult and pediatric patients without true IgE-mediated allergy or any mechanism of anaphylaxis when tested. This has created opportunities to use direct challenges to disprove these allergies at the point-of-care and improves antibiotic stewardship. Additional advances have highlighted cross-reactive str...
Source: Current Opinion in Pediatrics - November 7, 2022 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research

Drug allergy: diagnosis and management of drug allergy in adults, children and young people; a look at NICE guidance
Background When any patient uses a medicine, it has the ability to cause a noxious and unintended response known as an ‘adverse drug reaction’ (ADR). A drug allergy is defined as an ADR with specific clinical features compatible with an immunological mechanism that re-occurs on re-exposure to that offending drug. Sometimes, it can be a challenge to decide from the clinical history alone as to whether a drug reaction is allergic or not without the need for further investigations. Information about current guideline In September 2014, the National Institute for Health and Care Excellence (NICE) published a guidel...
Source: Archives of Disease in Childhood - Education and Practice - September 19, 2016 Category: Pediatrics Authors: Sadreddini, H. A. S., Starkey, E. S. Tags: Guideline review, Immunology (including allergy), Child health, Unwanted effects / adverse reactions, Asthma, Dermatology, Guidelines Source Type: research

B cells and food allergy
Purpose of review B cells are known in food allergy pathogenesis for their production of IgE but their roles in the development of tolerance to foods are not well understood. Further understanding of B-cell biology in the context of food allergy is essential for the creation of effective prevention strategies and therapies. Recent findings The majority of allergen-specific IgE in humans appears to arise from antigen-experienced B cells that have already undergone class switch recombination to other antibody isotypes, such as IgG1, and can also be produced by cells class switching to IgE locally in the gastrointe...
Source: Current Opinion in Pediatrics - November 10, 2021 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research

Pacifier Cleaning Practices and Risk of Allergy Development
CONCLUSIONS: Parental sucking of their infant’s pacifier may reduce the risk of allergy development, possibly via immune stimulation by microbes transferred to the infant via the parent’s saliva.
Source: PEDIATRICS - May 31, 2013 Category: Pediatrics Authors: Hesselmar, B., Sjoberg, F., Saalman, R., Aberg, N., Adlerberth, I., Wold, A. E. Tags: Allergy & Dermatology Article Source Type: research

Tree nut allergy: a systematic review
Purpose of review Systematic scoping review, focusing on randomized clinical trials of recent research addressing tree nut allergy. Recent findings This review addresses published, unpublished, and re-analyzed studies on tree nut allergy definition, epidemiology, etiology, diagnosis, prognosis, and therapy. Summary The importance of tree nut allergy spans nations, economies, and cultures. While broad themes in epidemiology, etiology, diagnosis, prognosis, and therapy are emerging, the next major advance in tree nut allergy will require large, robust studies to deliver results important to patients and families.
Source: Current Opinion in Pediatrics - November 7, 2022 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research

Child and Parental Reports of Bullying in a Consecutive Sample of Children With Food Allergy
CONCLUSIONS: Bullying is common in food-allergic children. It is associated with lower QoL and distress in children and their parents. Half of the bullying cases remain unknown to parents. When parents are aware of the bullying, the child’s QoL is better. It is important to proactively identify and address cases in this population.
Source: PEDIATRICS - January 1, 2013 Category: Pediatrics Authors: Shemesh, E., Annunziato, R. A., Ambrose, M. A., Ravid, N. L., Mullarkey, C., Rubes, M., Chuang, K., Sicherer, M., Sicherer, S. H. Tags: Allergy & Dermatology Article Source Type: research

The management of peanut allergy
Peanut allergy is common and can be a cause of severe, life-threatening reactions. It is rarely outgrown like other food allergies such as egg and milk. Measures aiming to reduce its prevalence via maternal avoidance during pregnancy and lactation, or delayed introduction into the diet, have failed to show any benefit. Peanut allergy has a significant effect on the quality of life of sufferers and their families due to dietary and social restrictions, but mainly stemming from fear of accidental peanut ingestion. The current management consists of strict avoidance, education and provision of emergency medication. Families f...
Source: Archives of Disease in Childhood - December 15, 2014 Category: Pediatrics Authors: Anagnostou, K., Clark, A. Tags: Editor's choice, Immunology (including allergy), Childhood nutrition, Diet, Pregnancy, Reproductive medicine, Childhood nutrition (paediatrics) Review Source Type: research