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Total 214 results found since Jan 2013.

Chapter 10: Sinonasal malignancies.
This article reviews the classification of malignant tumors of the paranasal sinuses, their clinical presentation, relevant diagnostic investigations, and the principals of therapy and management. PMID: 23711038 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2013 Category: ENT & OMF Authors: Harvey RJ, Dalgorf DM Tags: Am J Rhinol Allergy Source Type: research

Schneiderian papillomas: Comparative review of exophytic, oncocytic, and inverted types.
CONCLUSION: The inverted and exophytic type are the most common sinonasal papillomas, with the inverted type having an 8% rate of malignant transformation in this study. In contrast, the oncocytic type was not associated with dysplasia or malignancy in our series despite reports in the literature indicating malignant potential. History of CRS and papilloma location can provide clues to the histological subtype, which is important for surgical planning and patient counseling. PMID: 23883810 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - July 1, 2013 Category: ENT & OMF Authors: Vorasubin N, Vira D, Suh JD, Bhuta S, Wang MB Tags: Am J Rhinol Allergy Source Type: research

Anti Inflammatory, Gastrointestinal and Hepatoprotective Effects of Ocimum Sanctum Linn: an Ancient Remedy With New Application.
Abstract Herbal medicine has a long background equal to history of humankind. Several plants have been used as remedies in ancient Persian, Egyptian, Chinese and Indian civilizations. The plant Ocimum sanctum Linn. (Tulsi) is one of these medicinal plants with a wide variety of applications in traditional medicine. In modern era, it has been shown to be effective against diabetes mellitus, hypertension, cancers, bronchitis, and found to have anti-microbial properties. Several experimental studies have confirmed its anti-inflammatory properties and its role in modulation of both cellular and humeral immunity. Recen...
Source: Inflammation and Allergy Drug Targets - November 24, 2013 Category: Allergy & Immunology Authors: Kamyab AA, Eshraghian A Tags: Inflamm Allergy Drug Targets Source Type: research

HLA-G allele and Haplotype Frequencies in a Healthy Population of Iran.
According to this study, the most prevalent alleles in the Iranian population were G*01:01:01:01 (52.5%), G*01:01:02 (16%) and G*01:04:03 (14.5%) and also the lowest alleles regarding the frequency were G*01:01:01:06 (0.5%) and G*01:03 (0.5%). The results of G*01:01:01:01 and G*01:04:01 frequencies showed some similarities with the polish population. Our results were similar to the north Indian population for the frequencies of G*01:06 and G*01:01:02. PMID: 24659125 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - March 29, 2014 Category: Allergy & Immunology Authors: Kuroshli Z, Gourabi H, Bazrgar M, Sanati MH, Bahraminejad E, Anisi K Tags: Iran J Allergy Asthma Immunol Source Type: research

Survivin and cortactin expression in sinonasal schneiderian (inverted) papilloma and associated carcinoma.
CONCLUSION: Nuclear survivin expression was significantly higher in SCCs than in IPs. Prospective, multi-institutional prognostic studies, preferably on an international scale (given the few cases treated at single institutions), are needed to confirm the role of survivin in IP malignant transformation. PMID: 29644904 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - March 1, 2018 Category: ENT & OMF Authors: Marioni G, Brescia G, Nicolè L, Marchese-Ragona R, Barion U, Giacomelli L, Marino F, Martini A, Ottaviano G Tags: Am J Rhinol Allergy Source Type: research

Construction of a Recombinant Phage-vaccine Capable of Reducing the Growth Rate of an Established LL2 Tumor Model.
In conclusion, EM-L2 displaying phage particles could be deemed as an encouraging strategy in contemporary cancer immunotherapy. PMID: 29908541 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - June 1, 2018 Category: Allergy & Immunology Authors: Asadi-Ghalehni M, Rasaee MJ, Namvar Asl N, Khosravani M, Rajabibazl M, Khalili S, Modjtahedi H, Sadroddiny E Tags: Iran J Allergy Asthma Immunol Source Type: research

The Role Of Chitinase 3-Like –1 In The Regulation Of Food Allergy
Food allergy is an increasing health problem that has no approved treatment. Chitinase 3-like –1 (CHI3L1) is a type of chitinase-like proteins that lacks chitinase activity. CHI3L1 is highly expressed in a variety of cells, including macrophages, neutrophils and epithelial cells. Also, it is known to be associated with cancer and type 2 inflammation. However, the role of CHI3L1 in food all ergy has not been investigated.
Source: Journal of Allergy and Clinical Immunology - January 31, 2020 Category: Allergy & Immunology Authors: Eun Gyul Kim, Myunghyun Sohn Source Type: research

Immunogenicity Evaluation of Recombinant Edible Vaccine Candidate Containing HER2-MUC1 against Breast Cancer.
In this study, Her2, MUC1, and a novel fusion structure were expressed in the seeds and hairy roots of transgenic plants appropriately. The mice groups were immunized either by feeding of transgenic seeds or hairy roots. All immunized groups showed a considerable rise in anti-glycoprotein serum IgG and IgA, and IFNɣ cytokine. However, the animals received chimeric protein showed significant higher immune responses in comparison to ones received one of these immunogen. The results indicated that the oral immunization of an animal model with transgenic plants could effectively elicit immune responses against two major tumo...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 22, 2019 Category: Allergy & Immunology Authors: Mehrab Mohseni M, Amani J, Fasihi Ramandi M, Mahjoubi F, Jafaria M, Salmanian AH Tags: Iran J Allergy Asthma Immunol Source Type: research

Fibroblast Growth Factor 2 Augments Transforming Growth Factor Beta 1 Induced Epithelial-mesenchymal Transition in Lung Cell Culture Model.
This study suggests a synergistic effect between TGFβ1 and FGF2 in inducing EMT in lung epithelial cells, which may play an important role in wound healing and tissue repair after injury. PMID: 33463102 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - August 25, 2020 Category: Allergy & Immunology Authors: El-Baz LMF, Shoukry NM, Hafez HS, Guzy RD, Salem ML Tags: Iran J Allergy Asthma Immunol Source Type: research

Fibroblast Growth Factor 2 Augments Transforming Growth Factor Beta 1 Induced Epithelial-mesenchymal Transition in Lung Cell Culture Model
This study suggests a synergistic effect between TGFβ1 and FGF2 in inducing EMT in lung epithelial cells, which may play an important role in wound healing and tissue repair after injury.PMID:33463102 | DOI:10.18502/ijaai.v19i4.4110
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Lamis M F El-Baz Nahla M Shoukry Hani S Hafez Robert D Guzy Mohamed Labib Salem Source Type: research

Periostin in Allergy and Inflammation
Matricellular proteins are involved in the crosstalk between cells and their environment and thus play an important role in allergic and inflammatory reactions. Periostin, a matricellular protein, has several documented and multi-faceted roles in health and disease. It is differentially expressed, usually upregulated, in allergic conditions, a variety of inflammatory diseases as well as in cancer and contributes to the development and progression of these diseases. Periostin has also been shown to influence tissue remodelling, fibrosis, regeneration and repair. In allergic reactions periostin is involved in type 2 immunity...
Source: Frontiers in Immunology - August 27, 2021 Category: Allergy & Immunology Source Type: research

CircKIAA0368 Promotes Proliferation, Migration, and Invasion by Upregulating HOXA10 in Nasopharyngeal Carcinoma
CONCLUSION: CircKIAA0368 upregulates HOXA10 expression via miR-6838-5p and PCAF, consequently promoting NPCcell and tumor growth.PMID:35593126 | DOI:10.1177/19458924221100960
Source: American Journal of Rhinology and Allergy - May 20, 2022 Category: ENT & OMF Authors: Zhiping Chen Qiaoying Gong Daojing Li Juying Zhou Source Type: research