Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors
In conclusion, our data indicates that alamandine, through MrgD, attenuates anxiety-like behavior in male TGR(ASrAOGEN)680, which reinforces the importance of the counter-regulatory RAS axis as promising target for the treatment of neuropsychiatric disorders.PMID:38678724 | DOI:10.1016/j.yhbeh.2024.105551 (Source: Hormones and Behavior)
Source: Hormones and Behavior - April 28, 2024 Category: Endocrinology Authors: Laura Amado Costa Laura B Oliveira Amaral Fl ávio A G Mourão Michael Bader Robson A S Santos Maria Jos é Campagnole-Santos Lucas M Kangussu Source Type: research

Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors
In conclusion, our data indicates that alamandine, through MrgD, attenuates anxiety-like behavior in male TGR(ASrAOGEN)680, which reinforces the importance of the counter-regulatory RAS axis as promising target for the treatment of neuropsychiatric disorders.PMID:38678724 | DOI:10.1016/j.yhbeh.2024.105551 (Source: Hormones and Behavior)
Source: Hormones and Behavior - April 28, 2024 Category: Endocrinology Authors: Laura Amado Costa Laura B Oliveira Amaral Fl ávio A G Mourão Michael Bader Robson A S Santos Maria Jos é Campagnole-Santos Lucas M Kangussu Source Type: research

Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors
In conclusion, our data indicates that alamandine, through MrgD, attenuates anxiety-like behavior in male TGR(ASrAOGEN)680, which reinforces the importance of the counter-regulatory RAS axis as promising target for the treatment of neuropsychiatric disorders.PMID:38678724 | DOI:10.1016/j.yhbeh.2024.105551 (Source: Hormones and Behavior)
Source: Hormones and Behavior - April 28, 2024 Category: Endocrinology Authors: Laura Amado Costa Laura B Oliveira Amaral Fl ávio A G Mourão Michael Bader Robson A S Santos Maria Jos é Campagnole-Santos Lucas M Kangussu Source Type: research

Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors
In conclusion, our data indicates that alamandine, through MrgD, attenuates anxiety-like behavior in male TGR(ASrAOGEN)680, which reinforces the importance of the counter-regulatory RAS axis as promising target for the treatment of neuropsychiatric disorders.PMID:38678724 | DOI:10.1016/j.yhbeh.2024.105551 (Source: Hormones and Behavior)
Source: Hormones and Behavior - April 28, 2024 Category: Endocrinology Authors: Laura Amado Costa Laura B Oliveira Amaral Fl ávio A G Mourão Michael Bader Robson A S Santos Maria Jos é Campagnole-Santos Lucas M Kangussu Source Type: research

Does testosterone underly the interplay between male traits and territorial behavior in neotropical poison frogs?
Horm Behav. 2024 Apr 26;162:105547. doi: 10.1016/j.yhbeh.2024.105547. Online ahead of print.ABSTRACTThe ability of individual animals to defend a territory as well as various phenotypic and behavioral traits may be targets of sexual selection used by males to evaluate their competitors or by females to choose males. A frequent question in animal behavior is whether male traits and characteristics of their territory are correlated and what are the mechanisms that may mediate such associations when they exist. Because hormones link phenotype to behavior, by studying the role of testosterone in territoriality one may come clo...
Source: Hormones and Behavior - April 27, 2024 Category: Endocrinology Authors: Mileidy Betancourth-Cundar Virginie Canoine Leonida Fusani Carlos Daniel Cadena Source Type: research

Does testosterone underly the interplay between male traits and territorial behavior in neotropical poison frogs?
Horm Behav. 2024 Apr 26;162:105547. doi: 10.1016/j.yhbeh.2024.105547. Online ahead of print.ABSTRACTThe ability of individual animals to defend a territory as well as various phenotypic and behavioral traits may be targets of sexual selection used by males to evaluate their competitors or by females to choose males. A frequent question in animal behavior is whether male traits and characteristics of their territory are correlated and what are the mechanisms that may mediate such associations when they exist. Because hormones link phenotype to behavior, by studying the role of testosterone in territoriality one may come clo...
Source: Hormones and Behavior - April 27, 2024 Category: Endocrinology Authors: Mileidy Betancourth-Cundar Virginie Canoine Leonida Fusani Carlos Daniel Cadena Source Type: research

Developmental exposure to 17- α-hydroxyprogesterone caproate disrupts decision-making in adult female rats: A potential role for a dopaminergic mechanism
Horm Behav. 2024 Apr 25;163:105550. doi: 10.1016/j.yhbeh.2024.105550. Online ahead of print.ABSTRACTThe synthetic progestin, 17α-hydroxyprogesterone caproate (17-OHPC), is administered to pregnant individuals at risk for preterm birth and is likely transferred from mother to fetus. Yet, there is little information regarding the potential effects of 17-OHPC administration on behavioral and neural development in offspring. In rats, neonatal 17-OHPC exposure altered dopaminergic fiber distribution and density in the prelimbic medial prefrontal cortex (mPFC) in neonates and adolescents, respectively. Additionally, neonatal 17...
Source: Hormones and Behavior - April 26, 2024 Category: Endocrinology Authors: Paige L Graney Michael Y Chen Ruth I Wood Christine K Wagner Source Type: research

Prolactin is associated with proximity to incubating partner rather than parental care in black-headed gulls
In this study, we tested for associations between plasma prolactin and the expression of both parental care and proximity to the partner in incubating black-headed gulls, Chroicocephalus ridibundus. Baseline prolactin levels increased with calendar date but were unrelated to incubation behaviours. However, parents who showed a weaker decrease in prolactin to an acute stressor spent more time in close proximity to their incubating partner while not on the nest themselves, suggesting that individual variation in stress-induced prolactin changes reflect differences in parents' tendency to be closely associated with their part...
Source: Hormones and Behavior - April 25, 2024 Category: Endocrinology Authors: Kat Bebbington Charline Parenteau Olivier Chastel Ton G G Groothuis Source Type: research

Prolactin is associated with proximity to incubating partner rather than parental care in black-headed gulls
In this study, we tested for associations between plasma prolactin and the expression of both parental care and proximity to the partner in incubating black-headed gulls, Chroicocephalus ridibundus. Baseline prolactin levels increased with calendar date but were unrelated to incubation behaviours. However, parents who showed a weaker decrease in prolactin to an acute stressor spent more time in close proximity to their incubating partner while not on the nest themselves, suggesting that individual variation in stress-induced prolactin changes reflect differences in parents' tendency to be closely associated with their part...
Source: Hormones and Behavior - April 25, 2024 Category: Endocrinology Authors: Kat Bebbington Charline Parenteau Olivier Chastel Ton G G Groothuis Source Type: research

Testosterone, gender identity and gender-stereotyped personality attributes
In this study, we explored the relationships between testosterone, gender identity, and gender stereotyped personality attributes in a sample of over 400 university students (65 % female assigned at birth). Participants provided ratings of their self-perceived masculinity and femininity, resulting in a continuous measure of gender identity, and a set of agentic and communal personality attributes. A saliva sample was also provided for assay of basal testosterone. Results showed no compelling evidence that basal testosterone correlates with gender-stereotyped personality attributes or explains the relationship between sex/g...
Source: Hormones and Behavior - April 23, 2024 Category: Endocrinology Authors: Kathleen V Casto Dale J Cohen Modupe Akinola Pranjal H Mehta Source Type: research

Testosterone, gender identity and gender-stereotyped personality attributes
In this study, we explored the relationships between testosterone, gender identity, and gender stereotyped personality attributes in a sample of over 400 university students (65 % female assigned at birth). Participants provided ratings of their self-perceived masculinity and femininity, resulting in a continuous measure of gender identity, and a set of agentic and communal personality attributes. A saliva sample was also provided for assay of basal testosterone. Results showed no compelling evidence that basal testosterone correlates with gender-stereotyped personality attributes or explains the relationship between sex/g...
Source: Hormones and Behavior - April 23, 2024 Category: Endocrinology Authors: Kathleen V Casto Dale J Cohen Modupe Akinola Pranjal H Mehta Source Type: research

Testosterone, gender identity and gender-stereotyped personality attributes
In this study, we explored the relationships between testosterone, gender identity, and gender stereotyped personality attributes in a sample of over 400 university students (65 % female assigned at birth). Participants provided ratings of their self-perceived masculinity and femininity, resulting in a continuous measure of gender identity, and a set of agentic and communal personality attributes. A saliva sample was also provided for assay of basal testosterone. Results showed no compelling evidence that basal testosterone correlates with gender-stereotyped personality attributes or explains the relationship between sex/g...
Source: Hormones and Behavior - April 23, 2024 Category: Endocrinology Authors: Kathleen V Casto Dale J Cohen Modupe Akinola Pranjal H Mehta Source Type: research

Sex mechanisms as nonbinary influences on cognitive diversity
Horm Behav. 2024 Apr 20;162:105544. doi: 10.1016/j.yhbeh.2024.105544. Online ahead of print.ABSTRACTEssentially all neuropsychiatric diagnoses show some degree of sex and/or gender differences in their etiology, diagnosis, or prognosis. As a result, the roles of sex-related variables in behavior and cognition are of strong interest to many, with several lines of research showing effects on executive functions and value-based decision making in particular. These findings are often framed within a sex binary, with behavior of females described as less optimal than male "defaults"-- a framing that pits males and females again...
Source: Hormones and Behavior - April 21, 2024 Category: Endocrinology Authors: Nicola M Grissom Nic Glewwe Cathy Chen Erin Giglio Source Type: research

Longitudinal changes in sexual desire and attraction among women who started using the Natural Cycles app
Horm Behav. 2024 Apr 18;162:105546. doi: 10.1016/j.yhbeh.2024.105546. Online ahead of print.ABSTRACTMany women experience sexual side effects, such as decreased libido, when taking hormonal contraceptives (HCs). However, little is known about the extent to which libido recovers after discontinuing HCs, nor about the timeframe in which recovery is expected to occur. Given that HCs suppress the activities of multiple endogenous hormones that regulate both the ovulatory cycle and women's sexual function, resumption of cycles should predict libido recovery. Here, using a combination of repeated and retrospective measures, we e...
Source: Hormones and Behavior - April 19, 2024 Category: Endocrinology Authors: Jeffrey Gassen Summer Mengelkoch Divya Shanmugam Jack T Pearson Agathe van Lamsweerde Eleonora Benhar Sarah E Hill Source Type: research

Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring
Horm Behav. 2024 Apr 17;162:105548. doi: 10.1016/j.yhbeh.2024.105548. Online ahead of print.ABSTRACTThyroid hormones are crucial for brain development and their deficiency during fetal and postnatal periods can lead to mood and cognitive disorders. We aimed to examine the consequences of thyroid hormone deficiency on anxiety-related behaviors and protein expression of hippocampal glutamate transporters in congenital hypothyroid male offspring rats. Possible beneficial effects of treadmill exercise have also been examined. Congenital hypothyroidism was induced by adding propylthiouracil (PTU) to drinking water of pregnant W...
Source: Hormones and Behavior - April 18, 2024 Category: Endocrinology Authors: Zohreh Zare Sakineh Shafia Moslem Mohammadi Source Type: research