Fathers and sons, mothers and daughters: Sex-specific genetic architecture for fetal testosterone in a wild mammal
Horm Behav. 2024 Mar 6;161:105525. doi: 10.1016/j.yhbeh.2024.105525. Online ahead of print.ABSTRACTTestosterone plays a critical role in mediating fitness-related traits in many species. Although it is highly responsive to environmental and social conditions, evidence from several species show a heritable component to its individual variation. Despite the known effects that in utero testosterone exposure have on adult fitness, the heritable component of individual testosterone variation in fetuses is mostly unexplored. Furthermore, testosterone has sex-differential effects on fetal development, i.e., a specific level may b...
Source: Hormones and Behavior - March 7, 2024 Category: Endocrinology Authors: Ruth Fishman Simona Kralj-Fi šer Sivan Marglit Lee Koren Yoni Vortman Source Type: research
Social regulation of arginine vasopressin and oxytocin systems in a wild group-living fish
Horm Behav. 2024 Mar 6;161:105521. doi: 10.1016/j.yhbeh.2024.105521. Online ahead of print.ABSTRACTThe neuropeptides arginine vasopressin (AVP) and oxytocin (OXT) are key regulators of social behaviour across vertebrates. However, much of our understanding of how these neuropeptide systems interact with social behaviour is centred around laboratory studies which fail to capture the social and physiological challenges of living in the wild. To evaluate relationships between these neuropeptide systems and social behaviour in the wild, we studied social groups of the cichlid fish Neolamprologus pulcher in Lake Tanganyika, Afr...
Source: Hormones and Behavior - March 7, 2024 Category: Endocrinology Authors: Brett M Culbert Isaac Y Ligocki Matthew G Salena Marian Y L Wong Ian M Hamilton Nicholas J Bernier Sigal Balshine Source Type: research
The role of exogenous testosterone and social environment on the expression of sociosexuality and status-seeking behaviors in young Chilean men
Horm Behav. 2024 Mar 5;161:105522. doi: 10.1016/j.yhbeh.2024.105522. Online ahead of print.ABSTRACTTestosterone plays an important role as a social hormone. Current evidence suggests that testosterone is positively related to sociosexuality increasing the psychological attitudes toward investing in short-term versus long-term mating and promotes status-seeking behaviors both by dominance and prestige. In addition, the social environment may play an important role in the expression of mating effort through changes in sociosexuality and status-seeking behaviors. However, the causal relationships among the mentioned variables...
Source: Hormones and Behavior - March 6, 2024 Category: Endocrinology Authors: Pablo Polo Gabriela Fajardo Jose Antonio Mu ñoz-Reyes Nohelia T Valenzuela Montserrat Belinch ón Oriana Figueroa Ana Fern ández-Martínez Marcel Degl ín Miguel Pita Source Type: research
Low dose of propyl-pyrazole-triol, an agonist of estrogen receptor alpha, administration stimulates the Coolidge effect in fadrozole-treated male rats
Horm Behav. 2024 Mar 5;161:105520. doi: 10.1016/j.yhbeh.2024.105520. Online ahead of print.ABSTRACTEstrogen receptor (ER) α is involved in male sexual function. Here, we aim to investigate how ERα activation influences sexual satiety and the Coolidge effect (i.e., when a rat, that has reached sexual satiety, experiences an increased arousal after exposure to a novel sexual partner) in estrogen-deprived male rats. Male rats (8 per group) were treated daily for 29 days with either saline (Control group) or fadrozole dissolved in saline (1 mg/kg/day) 1 h before mating. On Days 13 and 29, rats treated with fadrozole received...
Source: Hormones and Behavior - March 6, 2024 Category: Endocrinology Authors: P Hanna C Corre Joanna M Mainwaring K Kenn Z Peralta P Mark Lokman Robert Porteous Erik Wibowo Source Type: research
The role of exogenous testosterone and social environment on the expression of sociosexuality and status-seeking behaviors in young Chilean men
Horm Behav. 2024 Mar 5;161:105522. doi: 10.1016/j.yhbeh.2024.105522. Online ahead of print.ABSTRACTTestosterone plays an important role as a social hormone. Current evidence suggests that testosterone is positively related to sociosexuality increasing the psychological attitudes toward investing in short-term versus long-term mating and promotes status-seeking behaviors both by dominance and prestige. In addition, the social environment may play an important role in the expression of mating effort through changes in sociosexuality and status-seeking behaviors. However, the causal relationships among the mentioned variables...
Source: Hormones and Behavior - March 6, 2024 Category: Endocrinology Authors: Pablo Polo Gabriela Fajardo Jose Antonio Mu ñoz-Reyes Nohelia T Valenzuela Montserrat Belinch ón Oriana Figueroa Ana Fern ández-Martínez Marcel Degl ín Miguel Pita Source Type: research
Low dose of propyl-pyrazole-triol, an agonist of estrogen receptor alpha, administration stimulates the Coolidge effect in fadrozole-treated male rats
Horm Behav. 2024 Mar 5;161:105520. doi: 10.1016/j.yhbeh.2024.105520. Online ahead of print.ABSTRACTEstrogen receptor (ER) α is involved in male sexual function. Here, we aim to investigate how ERα activation influences sexual satiety and the Coolidge effect (i.e., when a rat, that has reached sexual satiety, experiences an increased arousal after exposure to a novel sexual partner) in estrogen-deprived male rats. Male rats (8 per group) were treated daily for 29 days with either saline (Control group) or fadrozole dissolved in saline (1 mg/kg/day) 1 h before mating. On Days 13 and 29, rats treated with fadrozole received...
Source: Hormones and Behavior - March 6, 2024 Category: Endocrinology Authors: P Hanna C Corre Joanna M Mainwaring K Kenn Z Peralta P Mark Lokman Robert Porteous Erik Wibowo Source Type: research
G protein-coupled estrogen receptor (GPER) in the dorsal hippocampus regulates memory consolidation in gonadectomized male mice, likely via different signaling mechanisms than in female mice
Horm Behav. 2024 Feb 29;161:105516. doi: 10.1016/j.yhbeh.2024.105516. Online ahead of print.ABSTRACTStudies in ovariectomized (OVX) female rodents suggest that G protein-coupled estrogen receptor (GPER) is a key regulator of memory, yet little is known about its importance to memory in males or the cellular mechanisms underlying its mnemonic effects in either sex. In OVX mice, bilateral infusion of the GPER agonist G-1 into the dorsal hippocampus (DH) enhances object recognition and spatial memory consolidation in a manner dependent on rapid activation of c-Jun N-terminal kinase (JNK) signaling, cofilin phosphorylation, an...
Source: Hormones and Behavior - March 1, 2024 Category: Endocrinology Authors: Gustavo D B Machado Alexis L Schnitzler Aaron W Fleischer Sarah B Beamish Karyn M Frick Source Type: research
G protein-coupled estrogen receptor (GPER) in the dorsal hippocampus regulates memory consolidation in gonadectomized male mice, likely via different signaling mechanisms than in female mice
Horm Behav. 2024 Feb 29;161:105516. doi: 10.1016/j.yhbeh.2024.105516. Online ahead of print.ABSTRACTStudies in ovariectomized (OVX) female rodents suggest that G protein-coupled estrogen receptor (GPER) is a key regulator of memory, yet little is known about its importance to memory in males or the cellular mechanisms underlying its mnemonic effects in either sex. In OVX mice, bilateral infusion of the GPER agonist G-1 into the dorsal hippocampus (DH) enhances object recognition and spatial memory consolidation in a manner dependent on rapid activation of c-Jun N-terminal kinase (JNK) signaling, cofilin phosphorylation, an...
Source: Hormones and Behavior - March 1, 2024 Category: Endocrinology Authors: Gustavo D B Machado Alexis L Schnitzler Aaron W Fleischer Sarah B Beamish Karyn M Frick Source Type: research
G protein-coupled estrogen receptor (GPER) in the dorsal hippocampus regulates memory consolidation in gonadectomized male mice, likely via different signaling mechanisms than in female mice
Horm Behav. 2024 Feb 29;161:105516. doi: 10.1016/j.yhbeh.2024.105516. Online ahead of print.ABSTRACTStudies in ovariectomized (OVX) female rodents suggest that G protein-coupled estrogen receptor (GPER) is a key regulator of memory, yet little is known about its importance to memory in males or the cellular mechanisms underlying its mnemonic effects in either sex. In OVX mice, bilateral infusion of the GPER agonist G-1 into the dorsal hippocampus (DH) enhances object recognition and spatial memory consolidation in a manner dependent on rapid activation of c-Jun N-terminal kinase (JNK) signaling, cofilin phosphorylation, an...
Source: Hormones and Behavior - March 1, 2024 Category: Endocrinology Authors: Gustavo D B Machado Alexis L Schnitzler Aaron W Fleischer Sarah B Beamish Karyn M Frick Source Type: research
G protein-coupled estrogen receptor (GPER) in the dorsal hippocampus regulates memory consolidation in gonadectomized male mice, likely via different signaling mechanisms than in female mice
Horm Behav. 2024 Feb 29;161:105516. doi: 10.1016/j.yhbeh.2024.105516. Online ahead of print.ABSTRACTStudies in ovariectomized (OVX) female rodents suggest that G protein-coupled estrogen receptor (GPER) is a key regulator of memory, yet little is known about its importance to memory in males or the cellular mechanisms underlying its mnemonic effects in either sex. In OVX mice, bilateral infusion of the GPER agonist G-1 into the dorsal hippocampus (DH) enhances object recognition and spatial memory consolidation in a manner dependent on rapid activation of c-Jun N-terminal kinase (JNK) signaling, cofilin phosphorylation, an...
Source: Hormones and Behavior - March 1, 2024 Category: Endocrinology Authors: Gustavo D B Machado Alexis L Schnitzler Aaron W Fleischer Sarah B Beamish Karyn M Frick Source Type: research
The effects of diazepam on fear extinction in nulliparous and primiparous female rats
Horm Behav. 2024 Feb 28;161:105518. doi: 10.1016/j.yhbeh.2024.105518. Online ahead of print.ABSTRACTBenzodiazepines undermine the success of exposure therapy in humans with anxiety disorders, and impair the long-term memory of fear extinction (the laboratory basis of exposure therapy) in rodents. However, most rodent studies on fear extinction and benzodiazepines have been conducted in male rodents. In female rodents, the estrous cycle influences the consolidation of fear extinction memories and sensitivity to benzodiazepines. In addition, pregnancy leads to long-term changes in the neurobiological, hormonal, and behaviour...
Source: Hormones and Behavior - February 29, 2024 Category: Endocrinology Authors: Jodie E Pestana Tasfia Kabir Bronwyn M Graham Source Type: research
Neural thyroid hormone metabolism integrates seasonal changes in environmental temperature with the neuroendocrine reproductive axis
Horm Behav. 2024 Feb 28;161:105517. doi: 10.1016/j.yhbeh.2024.105517. Online ahead of print.ABSTRACTWe asked if environmental temperature alters thyroid hormone metabolism within the hypothalamus, thereby providing a neuroendocrine mechanism by which temperature could be integrated with photoperiod to regulate seasonal rhythms. We used immunohistochemistry to assess the effects of low-temperature winter dormancy at 4 °C or 12 °C on thyroid-stimulating hormone (TSH) within the infundibulum of the pituitary as well as deiodinase 2 (Dio2) and 3 (Dio3) within the hypothalamus of red-sided garter snakes (Thamnophis sirtalis)....
Source: Hormones and Behavior - February 29, 2024 Category: Endocrinology Authors: Deborah I Lutterschmidt Kalera Stratton Treven J Winters Stephanie Martin Lauren J Merlino Source Type: research
The effects of diazepam on fear extinction in nulliparous and primiparous female rats
Horm Behav. 2024 Feb 28;161:105518. doi: 10.1016/j.yhbeh.2024.105518. Online ahead of print.ABSTRACTBenzodiazepines undermine the success of exposure therapy in humans with anxiety disorders, and impair the long-term memory of fear extinction (the laboratory basis of exposure therapy) in rodents. However, most rodent studies on fear extinction and benzodiazepines have been conducted in male rodents. In female rodents, the estrous cycle influences the consolidation of fear extinction memories and sensitivity to benzodiazepines. In addition, pregnancy leads to long-term changes in the neurobiological, hormonal, and behaviour...
Source: Hormones and Behavior - February 29, 2024 Category: Endocrinology Authors: Jodie E Pestana Tasfia Kabir Bronwyn M Graham Source Type: research
Neural thyroid hormone metabolism integrates seasonal changes in environmental temperature with the neuroendocrine reproductive axis
Horm Behav. 2024 Feb 28;161:105517. doi: 10.1016/j.yhbeh.2024.105517. Online ahead of print.ABSTRACTWe asked if environmental temperature alters thyroid hormone metabolism within the hypothalamus, thereby providing a neuroendocrine mechanism by which temperature could be integrated with photoperiod to regulate seasonal rhythms. We used immunohistochemistry to assess the effects of low-temperature winter dormancy at 4 °C or 12 °C on thyroid-stimulating hormone (TSH) within the infundibulum of the pituitary as well as deiodinase 2 (Dio2) and 3 (Dio3) within the hypothalamus of red-sided garter snakes (Thamnophis sirtalis)....
Source: Hormones and Behavior - February 29, 2024 Category: Endocrinology Authors: Deborah I Lutterschmidt Kalera Stratton Treven J Winters Stephanie Martin Lauren J Merlino Source Type: research
Why biodiversity matters in the lab
Horm Behav. 2024 Feb 23;160:105509. doi: 10.1016/j.yhbeh.2024.105509. Online ahead of print.NO ABSTRACTPMID:38401333 | DOI:10.1016/j.yhbeh.2024.105509 (Source: Hormones and Behavior)
Source: Hormones and Behavior - February 24, 2024 Category: Endocrinology Authors: Richmond Thompson Yvon Delville Christine Lattin Source Type: research
