Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Horm Behav. 2023 Oct 7;156:105439. doi: 10.1016/j.yhbeh.2023.105439. Online ahead of print.ABSTRACTAnxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differences in susceptibility to negative valence behaviors relevant to anxiety disorders, we assayed avoidance behavior and cued threat memory dynamics in gonadally-intact adult male and female mice across four common inbred mouse strains: C57Bl/6J, 129S1/SVlmJ, DBA/2J, and BALB/cJ. Independent o...
Source: Hormones and Behavior - October 9, 2023 Category: Endocrinology Authors: Garret L Ryherd Averie L Bunce Haley A Edwards Nina E Baumgartner Elizabeth K Lucas Source Type: research
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Horm Behav. 2023 Oct 7;156:105439. doi: 10.1016/j.yhbeh.2023.105439. Online ahead of print.ABSTRACTAnxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differences in susceptibility to negative valence behaviors relevant to anxiety disorders, we assayed avoidance behavior and cued threat memory dynamics in gonadally-intact adult male and female mice across four common inbred mouse strains: C57Bl/6J, 129S1/SVlmJ, DBA/2J, and BALB/cJ. Independent o...
Source: Hormones and Behavior - October 9, 2023 Category: Endocrinology Authors: Garret L Ryherd Averie L Bunce Haley A Edwards Nina E Baumgartner Elizabeth K Lucas Source Type: research
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Horm Behav. 2023 Oct 7;156:105439. doi: 10.1016/j.yhbeh.2023.105439. Online ahead of print.ABSTRACTAnxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differences in susceptibility to negative valence behaviors relevant to anxiety disorders, we assayed avoidance behavior and cued threat memory dynamics in gonadally-intact adult male and female mice across four common inbred mouse strains: C57Bl/6J, 129S1/SVlmJ, DBA/2J, and BALB/cJ. Independent o...
Source: Hormones and Behavior - October 9, 2023 Category: Endocrinology Authors: Garret L Ryherd Averie L Bunce Haley A Edwards Nina E Baumgartner Elizabeth K Lucas Source Type: research
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Horm Behav. 2023 Oct 7;156:105439. doi: 10.1016/j.yhbeh.2023.105439. Online ahead of print.ABSTRACTAnxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differences in susceptibility to negative valence behaviors relevant to anxiety disorders, we assayed avoidance behavior and cued threat memory dynamics in gonadally-intact adult male and female mice across four common inbred mouse strains: C57Bl/6J, 129S1/SVlmJ, DBA/2J, and BALB/cJ. Independent o...
Source: Hormones and Behavior - October 9, 2023 Category: Endocrinology Authors: Garret L Ryherd Averie L Bunce Haley A Edwards Nina E Baumgartner Elizabeth K Lucas Source Type: research
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Horm Behav. 2023 Oct 7;156:105439. doi: 10.1016/j.yhbeh.2023.105439. Online ahead of print.ABSTRACTAnxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differences in susceptibility to negative valence behaviors relevant to anxiety disorders, we assayed avoidance behavior and cued threat memory dynamics in gonadally-intact adult male and female mice across four common inbred mouse strains: C57Bl/6J, 129S1/SVlmJ, DBA/2J, and BALB/cJ. Independent o...
Source: Hormones and Behavior - October 9, 2023 Category: Endocrinology Authors: Garret L Ryherd Averie L Bunce Haley A Edwards Nina E Baumgartner Elizabeth K Lucas Source Type: research
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Horm Behav. 2023 Oct 7;156:105439. doi: 10.1016/j.yhbeh.2023.105439. Online ahead of print.ABSTRACTAnxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differences in susceptibility to negative valence behaviors relevant to anxiety disorders, we assayed avoidance behavior and cued threat memory dynamics in gonadally-intact adult male and female mice across four common inbred mouse strains: C57Bl/6J, 129S1/SVlmJ, DBA/2J, and BALB/cJ. Independent o...
Source: Hormones and Behavior - October 9, 2023 Category: Endocrinology Authors: Garret L Ryherd Averie L Bunce Haley A Edwards Nina E Baumgartner Elizabeth K Lucas Source Type: research
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Horm Behav. 2023 Oct 7;156:105439. doi: 10.1016/j.yhbeh.2023.105439. Online ahead of print.ABSTRACTAnxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differences in susceptibility to negative valence behaviors relevant to anxiety disorders, we assayed avoidance behavior and cued threat memory dynamics in gonadally-intact adult male and female mice across four common inbred mouse strains: C57Bl/6J, 129S1/SVlmJ, DBA/2J, and BALB/cJ. Independent o...
Source: Hormones and Behavior - October 9, 2023 Category: Endocrinology Authors: Garret L Ryherd Averie L Bunce Haley A Edwards Nina E Baumgartner Elizabeth K Lucas Source Type: research
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Horm Behav. 2023 Oct 7;156:105439. doi: 10.1016/j.yhbeh.2023.105439. Online ahead of print.ABSTRACTAnxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differences in susceptibility to negative valence behaviors relevant to anxiety disorders, we assayed avoidance behavior and cued threat memory dynamics in gonadally-intact adult male and female mice across four common inbred mouse strains: C57Bl/6J, 129S1/SVlmJ, DBA/2J, and BALB/cJ. Independent o...
Source: Hormones and Behavior - October 9, 2023 Category: Endocrinology Authors: Garret L Ryherd Averie L Bunce Haley A Edwards Nina E Baumgartner Elizabeth K Lucas Source Type: research
Lack of evidence for coevolution between oxytocin receptor N-terminal variants and monogamy in placental mammals
Horm Behav. 2023 Oct 6;156:105437. doi: 10.1016/j.yhbeh.2023.105437. Online ahead of print.ABSTRACTOxytocin (OXT) is a neurohypophyseal hormone that influences a wide range of affiliative behaviors, such as pair-bonding and infant care, across mammals. The effects of OXT depend significantly on an adequate interaction with its receptor, OXTR. OXTR belongs to the G-protein coupled receptor family. The extracellular N-terminal domain of OXTR interacts with the linear C-terminal tail of OXT and is required for OXT binding. Across mammalian species there is a genetic diversity in OXTR terminal sequence. Previous work on primat...
Source: Hormones and Behavior - October 8, 2023 Category: Endocrinology Authors: Paola Cerrito Jeffrey K Spear Source Type: research
Urban and rural male song sparrows (Melospiza melodia) differ in territorial aggression and activation of vasotocin neurons in response to song challenge
Horm Behav. 2023 Oct 4;156:105438. doi: 10.1016/j.yhbeh.2023.105438. Online ahead of print.ABSTRACTWhen living in urban habitats, 'urban adapter' species often show greater aggression toward conspecifics, yet we do not understand the mechanisms underlying this behavioral shift. The neuroendocrine system regulates socio-sexual behaviors including aggression and thus could mediate behavioral responses to urbanization. Indeed, urban male song sparrows (Melospiza melodia), which are more territorially aggressive, also have greater abundance of the neuropeptide arginine vasotocin (AVT) in nodes of the brain social behavior netw...
Source: Hormones and Behavior - October 6, 2023 Category: Endocrinology Authors: Kendra B Sewall Michelle L Beck Samuel J Lane Scott Davies Source Type: research
Urban and rural male song sparrows (Melospiza melodia) differ in territorial aggression and activation of vasotocin neurons in response to song challenge
Horm Behav. 2023 Oct 4;156:105438. doi: 10.1016/j.yhbeh.2023.105438. Online ahead of print.ABSTRACTWhen living in urban habitats, 'urban adapter' species often show greater aggression toward conspecifics, yet we do not understand the mechanisms underlying this behavioral shift. The neuroendocrine system regulates socio-sexual behaviors including aggression and thus could mediate behavioral responses to urbanization. Indeed, urban male song sparrows (Melospiza melodia), which are more territorially aggressive, also have greater abundance of the neuropeptide arginine vasotocin (AVT) in nodes of the brain social behavior netw...
Source: Hormones and Behavior - October 6, 2023 Category: Endocrinology Authors: Kendra B Sewall Michelle L Beck Samuel J Lane Scott Davies Source Type: research
Urban and rural male song sparrows (Melospiza melodia) differ in territorial aggression and activation of vasotocin neurons in response to song challenge
Horm Behav. 2023 Oct 4;156:105438. doi: 10.1016/j.yhbeh.2023.105438. Online ahead of print.ABSTRACTWhen living in urban habitats, 'urban adapter' species often show greater aggression toward conspecifics, yet we do not understand the mechanisms underlying this behavioral shift. The neuroendocrine system regulates socio-sexual behaviors including aggression and thus could mediate behavioral responses to urbanization. Indeed, urban male song sparrows (Melospiza melodia), which are more territorially aggressive, also have greater abundance of the neuropeptide arginine vasotocin (AVT) in nodes of the brain social behavior netw...
Source: Hormones and Behavior - October 6, 2023 Category: Endocrinology Authors: Kendra B Sewall Michelle L Beck Samuel J Lane Scott Davies Source Type: research
Testosterone facilitates nonreproductive, context-appropriate pro- and anti-social behavior in female and male Mongolian gerbils
Horm Behav. 2023 Sep 28;156:105436. doi: 10.1016/j.yhbeh.2023.105436. Online ahead of print.ABSTRACTA growing body of literature suggests that testosterone (T) rapidly modulates behavior in a context-specific manner. However, the timescales in which T can rapidly mediate distinct types of behavior, such as pro- vs. anti- social responses, has not been studied. Thus, here we examined acute T influences on social behavior in male and female Mongolian gerbils in nonreproductive contexts. Females and males received an injection of either saline or T and were first tested in a social interaction test with a same-sex, familiar p...
Source: Hormones and Behavior - September 30, 2023 Category: Endocrinology Authors: Aubrey M Kelly Richmond R Thompson Source Type: research
Testosterone facilitates nonreproductive, context-appropriate pro- and anti-social behavior in female and male Mongolian gerbils
Horm Behav. 2023 Sep 28;156:105436. doi: 10.1016/j.yhbeh.2023.105436. Online ahead of print.ABSTRACTA growing body of literature suggests that testosterone (T) rapidly modulates behavior in a context-specific manner. However, the timescales in which T can rapidly mediate distinct types of behavior, such as pro- vs. anti- social responses, has not been studied. Thus, here we examined acute T influences on social behavior in male and female Mongolian gerbils in nonreproductive contexts. Females and males received an injection of either saline or T and were first tested in a social interaction test with a same-sex, familiar p...
Source: Hormones and Behavior - September 30, 2023 Category: Endocrinology Authors: Aubrey M Kelly Richmond R Thompson Source Type: research
Testosterone facilitates nonreproductive, context-appropriate pro- and anti-social behavior in female and male Mongolian gerbils
Horm Behav. 2023 Sep 28;156:105436. doi: 10.1016/j.yhbeh.2023.105436. Online ahead of print.ABSTRACTA growing body of literature suggests that testosterone (T) rapidly modulates behavior in a context-specific manner. However, the timescales in which T can rapidly mediate distinct types of behavior, such as pro- vs. anti- social responses, has not been studied. Thus, here we examined acute T influences on social behavior in male and female Mongolian gerbils in nonreproductive contexts. Females and males received an injection of either saline or T and were first tested in a social interaction test with a same-sex, familiar p...
Source: Hormones and Behavior - September 30, 2023 Category: Endocrinology Authors: Aubrey M Kelly Richmond R Thompson Source Type: research
