Sex differences in responses to aggressive encounters among California mice
In this study, we compared behavioral responses in both male and female adult California mice based on if they had 0, 1, or 3 aggressive encounters using a resident intruder paradigm. We measured how arginine vasopressin and oxytocin cells in the paraventricular nucleus responded to aggression using c-fos immunohistochemistry. We saw that both sexes disengaged from intruders with repeated aggressive encounters, but that on the final day of testing females were more likely to freeze when they encountered intruders compared to no aggression controls - which was not significant in males. Finally, we saw that percent of argini...
Source: Hormones and Behavior - April 6, 2024 Category: Endocrinology Authors: Jace X Kuske Alexandra Serna Godoy Alison V Ramirez Brian C Trainor Source Type: research
Effects of the combination of chronic unpredictable stress and environmental enrichment on anxiety-like behavior assessed using the elevated plus maze in Swiss male mice: Hypothalamus-Pituitary-Adrenal Axis-mediated mechanisms
In this study, our objective was to explore how chronic unpredictable stress (CUS) impacts anxiety-related behaviors in male Swiss mice raised in EE conditions. Additionally, we investigated corticosterone and adrenocorticotropic hormone (ACTH) levels to assess the involvement of the hypothalamic-pituitary-adrenal (HPA) axis in mediating these responses. Mice were housed under either EE or standard housing conditions for 21 days. Afterward, they were exposed to 11 days of CUS while still reared in their distinct housing conditions, with half of the mice receiving daily pretreatment with the vehicle and the other half recei...
Source: Hormones and Behavior - April 4, 2024 Category: Endocrinology Authors: Ariadne Elisa Belo-Silva Nivea Karla de Gusm ão Taveiros Silva Priscila Marianno Gabriel de Ara újo Costa Veridiana Petenati da Rovare Alexis Bailey Carolina Demarchi Munhoz Leonardo Santana Novaes Rosana Camarini Source Type: research
Effects of the combination of chronic unpredictable stress and environmental enrichment on anxiety-like behavior assessed using the elevated plus maze in Swiss male mice: Hypothalamus-Pituitary-Adrenal Axis-mediated mechanisms
In this study, our objective was to explore how chronic unpredictable stress (CUS) impacts anxiety-related behaviors in male Swiss mice raised in EE conditions. Additionally, we investigated corticosterone and adrenocorticotropic hormone (ACTH) levels to assess the involvement of the hypothalamic-pituitary-adrenal (HPA) axis in mediating these responses. Mice were housed under either EE or standard housing conditions for 21 days. Afterward, they were exposed to 11 days of CUS while still reared in their distinct housing conditions, with half of the mice receiving daily pretreatment with the vehicle and the other half recei...
Source: Hormones and Behavior - April 4, 2024 Category: Endocrinology Authors: Ariadne Elisa Belo-Silva Nivea Karla de Gusm ão Taveiros Silva Priscila Marianno Gabriel de Ara újo Costa Veridiana Petenati da Rovare Alexis Bailey Carolina Demarchi Munhoz Leonardo Santana Novaes Rosana Camarini Source Type: research
Effects of the combination of chronic unpredictable stress and environmental enrichment on anxiety-like behavior assessed using the elevated plus maze in Swiss male mice: Hypothalamus-Pituitary-Adrenal Axis-mediated mechanisms
In this study, our objective was to explore how chronic unpredictable stress (CUS) impacts anxiety-related behaviors in male Swiss mice raised in EE conditions. Additionally, we investigated corticosterone and adrenocorticotropic hormone (ACTH) levels to assess the involvement of the hypothalamic-pituitary-adrenal (HPA) axis in mediating these responses. Mice were housed under either EE or standard housing conditions for 21 days. Afterward, they were exposed to 11 days of CUS while still reared in their distinct housing conditions, with half of the mice receiving daily pretreatment with the vehicle and the other half recei...
Source: Hormones and Behavior - April 4, 2024 Category: Endocrinology Authors: Ariadne Elisa Belo-Silva Nivea Karla de Gusm ão Taveiros Silva Priscila Marianno Gabriel de Ara újo Costa Veridiana Petenati da Rovare Alexis Bailey Carolina Demarchi Munhoz Leonardo Santana Novaes Rosana Camarini Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Effects of paternal deprivation on empathetic behavior and the involvement of oxytocin receptors in the anterior cingulate cortex
Horm Behav. 2024 Mar 23;162:105536. doi: 10.1016/j.yhbeh.2024.105536. Online ahead of print.ABSTRACTPaternal deprivation (PD) impairs social cognition and sociality and increases levels of anxiety-like behavior. However, whether PD affects the levels of empathy in offspring and its underlying mechanisms remain unknown. The present study found that PD increased anxiety-like behavior in mandarin voles (Microtus mandarinus), impaired sociality, reduced the ability of emotional contagion, and the level of consolation behavior. Meanwhile, PD reduced OT neurons in the paraventricular nucleus (PVN) in both male and female mandari...
Source: Hormones and Behavior - March 24, 2024 Category: Endocrinology Authors: Wenjuan Hou Huan Ma Caihong Huang Yin Li Lu Li Lizi Zhang Yishan Qu Yufeng Xun Qixuan Yang Zhixiong He Fadao Tai Source Type: research
Letrozole delays acquisition of water maze task in female BALB/c mice: Possible involvement of anxiety
Horm Behav. 2024 Mar 20;162:105524. doi: 10.1016/j.yhbeh.2024.105524. Online ahead of print.ABSTRACTLetrozole, an aromatase inhibitor preventing estrogen synthesis from testosterone, is used as an adjuvant therapy in estrogen receptor-positive breast cancer patients. However, like other aromatase inhibitors, it induces many side effects, including impaired cognition. Despite its negative effect in humans, results from animal models are inconsistent and suggest that letrozole can either impair or improve cognition. Here, we studied the effects of chronic letrozole treatment on cognitive behavior of adult female BALB/c mice,...
Source: Hormones and Behavior - March 21, 2024 Category: Endocrinology Authors: Jacek Mamczarz Malcolm Lane Istvan Merchenthaler Source Type: research
Early life conditions reduce similarity between reproductive partners in HPA axis response to stress
Horm Behav. 2024 Mar 20;162:105508. doi: 10.1016/j.yhbeh.2024.105508. Online ahead of print.ABSTRACTSocial environments modulate endocrine function, yet it is unclear whether individuals can become like their social partners in how they physiologically respond to stressors. This social transmission of hypothalamic-pituitary-adrenal (HPA) axis reactivity could have long-term consequences for health and lifespan of individuals if their social partners react to stressors with an exaggerated HPA axis response. We tested whether glucocorticoid levels in response to stress of breeding partners changes after breeding depending on...
Source: Hormones and Behavior - March 21, 2024 Category: Endocrinology Authors: Buddhamas P Kriengwatana Christopher J Marshall Tyler Stevenson Pat Monaghan Source Type: research
