Letrozole delays acquisition of water maze task in female BALB/c mice: Possible involvement of anxiety
Horm Behav. 2024 Mar 20;162:105524. doi: 10.1016/j.yhbeh.2024.105524. Online ahead of print.ABSTRACTLetrozole, an aromatase inhibitor preventing estrogen synthesis from testosterone, is used as an adjuvant therapy in estrogen receptor-positive breast cancer patients. However, like other aromatase inhibitors, it induces many side effects, including impaired cognition. Despite its negative effect in humans, results from animal models are inconsistent and suggest that letrozole can either impair or improve cognition. Here, we studied the effects of chronic letrozole treatment on cognitive behavior of adult female BALB/c mice,...
Source: Hormones and Behavior - March 21, 2024 Category: Endocrinology Authors: Jacek Mamczarz Malcolm Lane Istvan Merchenthaler Source Type: research
Early life conditions reduce similarity between reproductive partners in HPA axis response to stress
Horm Behav. 2024 Mar 20;162:105508. doi: 10.1016/j.yhbeh.2024.105508. Online ahead of print.ABSTRACTSocial environments modulate endocrine function, yet it is unclear whether individuals can become like their social partners in how they physiologically respond to stressors. This social transmission of hypothalamic-pituitary-adrenal (HPA) axis reactivity could have long-term consequences for health and lifespan of individuals if their social partners react to stressors with an exaggerated HPA axis response. We tested whether glucocorticoid levels in response to stress of breeding partners changes after breeding depending on...
Source: Hormones and Behavior - March 21, 2024 Category: Endocrinology Authors: Buddhamas P Kriengwatana Christopher J Marshall Tyler Stevenson Pat Monaghan Source Type: research
Letrozole delays acquisition of water maze task in female BALB/c mice: Possible involvement of anxiety
Horm Behav. 2024 Mar 20;162:105524. doi: 10.1016/j.yhbeh.2024.105524. Online ahead of print.ABSTRACTLetrozole, an aromatase inhibitor preventing estrogen synthesis from testosterone, is used as an adjuvant therapy in estrogen receptor-positive breast cancer patients. However, like other aromatase inhibitors, it induces many side effects, including impaired cognition. Despite its negative effect in humans, results from animal models are inconsistent and suggest that letrozole can either impair or improve cognition. Here, we studied the effects of chronic letrozole treatment on cognitive behavior of adult female BALB/c mice,...
Source: Hormones and Behavior - March 21, 2024 Category: Endocrinology Authors: Jacek Mamczarz Malcolm Lane Istvan Merchenthaler Source Type: research
Early life conditions reduce similarity between reproductive partners in HPA axis response to stress
Horm Behav. 2024 Mar 20;162:105508. doi: 10.1016/j.yhbeh.2024.105508. Online ahead of print.ABSTRACTSocial environments modulate endocrine function, yet it is unclear whether individuals can become like their social partners in how they physiologically respond to stressors. This social transmission of hypothalamic-pituitary-adrenal (HPA) axis reactivity could have long-term consequences for health and lifespan of individuals if their social partners react to stressors with an exaggerated HPA axis response. We tested whether glucocorticoid levels in response to stress of breeding partners changes after breeding depending on...
Source: Hormones and Behavior - March 21, 2024 Category: Endocrinology Authors: Buddhamas P Kriengwatana Christopher J Marshall Tyler Stevenson Pat Monaghan Source Type: research
The paradox of spring: Thyroid and glucocorticoid responses to cold temperatures and food availability in free living Carneddau ponies
Horm Behav. 2024 Mar 18;161:105526. doi: 10.1016/j.yhbeh.2024.105526. Online ahead of print.ABSTRACTIn seasonal environments, maintaining a constant body temperature poses challenges for endotherms. Cold winters at high latitudes, with limited food availability, create opposing demands on metabolism: upregulation preserves body temperature but depletes energy reserves. Examining endocrine profiles, such as thyroid hormone triiodothyronine (T3) and glucocorticoids (GCs), proxies for changes in metabolic rate and acute stressors, offer insights into physiological trade-offs. We evaluated how environmental conditions and gest...
Source: Hormones and Behavior - March 19, 2024 Category: Endocrinology Authors: Jessica Granweiler Jurgi Crist óbal-Azkarate Nathan Morton Rupert Palme Susanne Shultz Source Type: research
Androgen regulation of behavioral stress responses and the hypothalamic-pituitary-adrenal axis
Horm Behav. 2024 Mar 18;162:105528. doi: 10.1016/j.yhbeh.2024.105528. Online ahead of print.ABSTRACTTestosterone is a powerful steroid hormone that can impact the brain and behavior in various ways, including regulating behavioral and neuroendocrine (hypothalamic-pituitary-adrenal (HPA) axis) stress responses. Early in life androgens can act to alter development of brain regions associated with stress regulation, which ultimately impacts the display of stress responses later in life. Adult circulating androgens can also influence the expression of distinct genes and proteins that regulate stress responses. These changes in...
Source: Hormones and Behavior - March 19, 2024 Category: Endocrinology Authors: Damian G Zuloaga Jennifer J Lafrican Kristen L Zuloaga Source Type: research
The paradox of spring: Thyroid and glucocorticoid responses to cold temperatures and food availability in free living Carneddau ponies
Horm Behav. 2024 Mar 18;161:105526. doi: 10.1016/j.yhbeh.2024.105526. Online ahead of print.ABSTRACTIn seasonal environments, maintaining a constant body temperature poses challenges for endotherms. Cold winters at high latitudes, with limited food availability, create opposing demands on metabolism: upregulation preserves body temperature but depletes energy reserves. Examining endocrine profiles, such as thyroid hormone triiodothyronine (T3) and glucocorticoids (GCs), proxies for changes in metabolic rate and acute stressors, offer insights into physiological trade-offs. We evaluated how environmental conditions and gest...
Source: Hormones and Behavior - March 19, 2024 Category: Endocrinology Authors: Jessica Granweiler Jurgi Crist óbal-Azkarate Nathan Morton Rupert Palme Susanne Shultz Source Type: research
Androgen regulation of behavioral stress responses and the hypothalamic-pituitary-adrenal axis
Horm Behav. 2024 Mar 18;162:105528. doi: 10.1016/j.yhbeh.2024.105528. Online ahead of print.ABSTRACTTestosterone is a powerful steroid hormone that can impact the brain and behavior in various ways, including regulating behavioral and neuroendocrine (hypothalamic-pituitary-adrenal (HPA) axis) stress responses. Early in life androgens can act to alter development of brain regions associated with stress regulation, which ultimately impacts the display of stress responses later in life. Adult circulating androgens can also influence the expression of distinct genes and proteins that regulate stress responses. These changes in...
Source: Hormones and Behavior - March 19, 2024 Category: Endocrinology Authors: Damian G Zuloaga Jennifer J Lafrican Kristen L Zuloaga Source Type: research
Prolactin promotes the recruitment of main olfactory bulb cells and enhances the behavioral exploration toward a socio-sexual stimulus in female mice
Horm Behav. 2024 Mar 15;162:105527. doi: 10.1016/j.yhbeh.2024.105527. Online ahead of print.ABSTRACTOlfactory communication is triggered by pheromones that profoundly influence neuroendocrine responses to drive social interactions. Two principal olfactory systems process pheromones: the main and the vomeronasal or accessory system. Prolactin receptors are expressed in both systems suggesting a participation in the processing of olfactory information. We previously reported that prolactin participates in the sexual and olfactory bulb maturation of females. Therefore, we explored the expression of prolactin receptors within ...
Source: Hormones and Behavior - March 16, 2024 Category: Endocrinology Authors: Viridiana Cerbantez-Bueno Ver ónica Viñuela-Berni Daniel Eduardo Mu ñoz-Mayorga Teresa Morales Rebeca Corona Source Type: research
Conditioned preferences: Gated by experience, context, and endocrine systems
Horm Behav. 2024 Mar 15;161:105529. doi: 10.1016/j.yhbeh.2024.105529. Online ahead of print.ABSTRACTCentral to the navigation of an ever-changing environment is the ability to form positive associations with places and conspecifics. The functions of location and social conditioned preferences are often studied independently, limiting our understanding of their interplay. Furthermore, a de-emphasis on natural functions of conditioned preferences has led to neurobiological interpretations separated from ecological context. By adopting a naturalistic and ethological perspective, we uncover complexities underlying the expressi...
Source: Hormones and Behavior - March 16, 2024 Category: Endocrinology Authors: Patrick K Monari Emma R Hammond Xin Zhao Alyse N Maksimoski Radmila Petric Candice L Malone Lauren V Riters Catherine A Marler Source Type: research
Prolactin promotes the recruitment of main olfactory bulb cells and enhances the behavioral exploration toward a socio-sexual stimulus in female mice
Horm Behav. 2024 Mar 15;162:105527. doi: 10.1016/j.yhbeh.2024.105527. Online ahead of print.ABSTRACTOlfactory communication is triggered by pheromones that profoundly influence neuroendocrine responses to drive social interactions. Two principal olfactory systems process pheromones: the main and the vomeronasal or accessory system. Prolactin receptors are expressed in both systems suggesting a participation in the processing of olfactory information. We previously reported that prolactin participates in the sexual and olfactory bulb maturation of females. Therefore, we explored the expression of prolactin receptors within ...
Source: Hormones and Behavior - March 16, 2024 Category: Endocrinology Authors: Viridiana Cerbantez-Bueno Ver ónica Viñuela-Berni Daniel Eduardo Mu ñoz-Mayorga Teresa Morales Rebeca Corona Source Type: research
Conditioned preferences: Gated by experience, context, and endocrine systems
Horm Behav. 2024 Mar 15;161:105529. doi: 10.1016/j.yhbeh.2024.105529. Online ahead of print.ABSTRACTCentral to the navigation of an ever-changing environment is the ability to form positive associations with places and conspecifics. The functions of location and social conditioned preferences are often studied independently, limiting our understanding of their interplay. Furthermore, a de-emphasis on natural functions of conditioned preferences has led to neurobiological interpretations separated from ecological context. By adopting a naturalistic and ethological perspective, we uncover complexities underlying the expressi...
Source: Hormones and Behavior - March 16, 2024 Category: Endocrinology Authors: Patrick K Monari Emma R Hammond Xin Zhao Alyse N Maksimoski Radmila Petric Candice L Malone Lauren V Riters Catherine A Marler Source Type: research
Prolactin promotes the recruitment of main olfactory bulb cells and enhances the behavioral exploration toward a socio-sexual stimulus in female mice
Horm Behav. 2024 Mar 15;162:105527. doi: 10.1016/j.yhbeh.2024.105527. Online ahead of print.ABSTRACTOlfactory communication is triggered by pheromones that profoundly influence neuroendocrine responses to drive social interactions. Two principal olfactory systems process pheromones: the main and the vomeronasal or accessory system. Prolactin receptors are expressed in both systems suggesting a participation in the processing of olfactory information. We previously reported that prolactin participates in the sexual and olfactory bulb maturation of females. Therefore, we explored the expression of prolactin receptors within ...
Source: Hormones and Behavior - March 16, 2024 Category: Endocrinology Authors: Viridiana Cerbantez-Bueno Ver ónica Viñuela-Berni Daniel Eduardo Mu ñoz-Mayorga Teresa Morales Rebeca Corona Source Type: research
Conditioned preferences: Gated by experience, context, and endocrine systems
Horm Behav. 2024 Mar 15;161:105529. doi: 10.1016/j.yhbeh.2024.105529. Online ahead of print.ABSTRACTCentral to the navigation of an ever-changing environment is the ability to form positive associations with places and conspecifics. The functions of location and social conditioned preferences are often studied independently, limiting our understanding of their interplay. Furthermore, a de-emphasis on natural functions of conditioned preferences has led to neurobiological interpretations separated from ecological context. By adopting a naturalistic and ethological perspective, we uncover complexities underlying the expressi...
Source: Hormones and Behavior - March 16, 2024 Category: Endocrinology Authors: Patrick K Monari Emma R Hammond Xin Zhao Alyse N Maksimoski Radmila Petric Candice L Malone Lauren V Riters Catherine A Marler Source Type: research
Glucocorticoid response to naturalistic interactions between children and dogs
This study builds on previous work that investigated potential stress-buffering effects of human-animal interaction during explicit stressors and demonstrates important physiological correlates of naturalistic interactions between children and dogs, similar to those that occur in daily life.PMID:38484567 | DOI:10.1016/j.yhbeh.2024.105523 (Source: Hormones and Behavior)
Source: Hormones and Behavior - March 14, 2024 Category: Endocrinology Authors: Gitanjali E Gnanadesikan Elizabeth Carranza Katherine M King Abigail C Flyer Gianna Ossello Paige G Smith Netzin G Steklis H Dieter Steklis Jessica J Connelly Melissa Barnett Nancy Gee Stacey Tecot Evan L MacLean Source Type: research
