Evaluation of the < em > ATM < /em > L2307F germline variant in 121 Italian pedigrees with familial myeloproliferative neoplasms
Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2024.285539. Online ahead of print.ABSTRACTNot available.PMID:38654656 | DOI:10.3324/haematol.2024.285539 (Source: Haematologica)
Source: Haematologica - April 24, 2024 Category: Hematology Authors: Oscar Borsani Roland J äger Daniela Pietra Ines Flieder Giacomo Riccaboni Robert Kralovics Elisa Rumi Source Type: research
Follicular lymphoma treatment decisions: put GELF on the shelf?
Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2024.285286. Online ahead of print.ABSTRACTNot available.PMID:38654659 | DOI:10.3324/haematol.2024.285286 (Source: Haematologica)
Source: Haematologica - April 24, 2024 Category: Hematology Authors: Brian K Link Source Type: research
Time from diagnosis to treatment has no impact on survival in newly diagnosed acute myeloid leukemia treated with venetoclax-based regimens
Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2024.285225. Online ahead of print.ABSTRACTIn newly diagnosed acute myeloid leukemia, immediate initiation of treatment is standard of care. However, deferral of antileukemic therapy may be indicated to assess comorbidities or pre-therapeutic risk factors. We explored the impact of time from diagnosis to treatment on outcomes in newly diagnosed acute myeloid leukemia undergoing venetoclax-based therapy in two distinct cohorts. By querying the Study Alliance Leukemia database and the global health network TriNetX, we identified 138 and 717 patients respectively with an avera...
Source: Haematologica - April 24, 2024 Category: Hematology Authors: David Baden Sven Zukunft Gema Hernandez Nadine Wolgast Sophie Steinhauser Alexander Pohlmann Christoph Schliemann Jan-Henrik Mikesch Bjorn Steffen Tim Sauer Maher Hanoun Kerstin Schafer-Eckart Stefan W Krause Mathias Hanel Hermann Einsele Edgar Jost Tim H Source Type: research
Central nervous system prophylaxis: it's time to start from scratch
Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2024.285425. Online ahead of print.ABSTRACTNot available.PMID:38654662 | DOI:10.3324/haematol.2024.285425 (Source: Haematologica)
Source: Haematologica - April 24, 2024 Category: Hematology Authors: Diego Villa Source Type: research
Differential activation of basal and IL-7-induced PI3K/Akt/mTOR and JAK/STAT5 signaling distinguishes pediatric from adult acute lymphoblastic leukemia
Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2023.284102. Online ahead of print.ABSTRACTNot available.PMID:38654666 | DOI:10.3324/haematol.2023.284102 (Source: Haematologica)
Source: Haematologica - April 24, 2024 Category: Hematology Authors: Marta B Fernandes A Margarida Gomes Mariana L Oliveira Joana Caldas Paulo L úcio Rathana Kim Aur élie Caye-Eude Filomena Pereira Aida B De Sousa Alessia De Stefano Matilde Y Follo Maria V Soares Jo ão F Lacerda Joana Desterro H élène Cavé Emmanuelle Source Type: research
Monocyte response to SARS-CoV-2 protein ORF8 is associated with severe COVID-19 infection in patients with chronic lymphocytic leukemia
Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2023.284617. Online ahead of print.ABSTRACTThe open reading frame 8 (ORF8) protein, encoded by the SARS-CoV-2 virus after infection, stimulates monocytes/macrophages to produce pro-inflammatory cytokines. We hypothesized that a positive ex vivo monocyte response to ORF8 protein pre-COVID-19 would be associated with subsequent severe COVID-19. We tested ORF8 ex vivo on peripheral blood mononuclear cells (PBMCs) from 26 anonymous healthy blood donors and measured intracellular cytokine/chemokine levels in monocytes by flow cytometry. The % monocytes staining positive in the s...
Source: Haematologica - April 24, 2024 Category: Hematology Authors: Gordon J Ruan Xiaosheng Wu Kimberly A Gwin Michelle K Manske Jithma P Abeykoon Vaishali Bhardwaj Taylor L Witter Matthew J Schellenberg Kari G Rabe Neil E Kay Sameer A Parikh Thomas E Witzig Source Type: research
Do it once, but do it right
Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2024.285246. Online ahead of print.ABSTRACTNot available.PMID:38654683 | DOI:10.3324/haematol.2024.285246 (Source: Haematologica)
Source: Haematologica - April 24, 2024 Category: Hematology Authors: Layal Yasin Arndt Borkhardt Source Type: research
< em > TP3 < /em > binding domain mutations are bad news in Burkitt lymphoma
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285213. Online ahead of print.ABSTRACTNot available.PMID:38634119 | DOI:10.3324/haematol.2024.285213 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Mitchell S Cairo Source Type: research
< em > IRF4-BLOC1S5 < /em > : the first rearrangement gene identified in TEMPI syndrome
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2023.284727. Online ahead of print.ABSTRACTNot available.PMID:38634121 | DOI:10.3324/haematol.2023.284727 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Ming Zhao Jia Liu Qing Yu Wenbin Xu Zilu Zhang Ze Fu Mingyuan Jia Xinyi Zeng Chengyu Wu Chenjing Ye Chao Wu Yingli Wu Ruibao Ren Junmin Li Kankan Wang Hua Yan Source Type: research
Validation of mutated < em > CEBPA < /em > bZIP as a distinct prognosis entity in acute myeloid leukemia: a study by the Spanish PETHEMA registry
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2023.284601. Online ahead of print.ABSTRACTNot available.PMID:38634126 | DOI:10.3324/haematol.2023.284601 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Esther Prados De la Torre Josefina Serrano David Mart ínez-Cuadrón Laura Torres Claudia Sargas Rosa Ayala Cristina Bilbao-Sieyro Mar ía Carmen Chillón Mar ía José Larráyoz Elena Soria Clara Aparicio-P érez Juan M Bergua Teresa Bernal Cristina Gil Source Type: research
Beyond adenosine triphosphate: unveiling the pleiotropic effects of pyruvate kinase activation in sickle cell anemia
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285390. Online ahead of print.ABSTRACTNot available.PMID:38634127 | DOI:10.3324/haematol.2024.285390 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Andreas Glenth øj Source Type: research
'One way, or another, I'm gonna find ya': miR-221-3p finds its targets < em > via < /em > small extracellular vesicles
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285257. Online ahead of print.ABSTRACTNot available.PMID:38634128 | DOI:10.3324/haematol.2024.285257 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Jonathan Tak-Sum Chow Leonardo Salmena Source Type: research
Outcome of infants with acute lymphoblastic leukemia treated with the Chinese Children's Cancer Group Acute Lymphoblastic Leukemia 2015 study protocol
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285201. Online ahead of print.ABSTRACTNot available.PMID:38634141 | DOI:10.3324/haematol.2024.285201 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Alex Wk Leung Jiaoyang Cai Zhi Wan Jiefen Qin Yongjun Fang Lirong Sun Jiashi Zhu Shaoyan Hu Ningling Wang Pan Gao Xin Tian Xiaofan Zhu Fen Zhou Xuedong Wu Xiuli Ju Xiaowen Zhai Hua Jiang Qun Hu Changda Liang Liangchun Yang Hui Zhang Jingyan Tang Ju Gao Ch Source Type: research
Hypomethylating agents are associated with high rates of hematologic toxicity in patients with secondary myeloid neoplasms developing after acquired aplastic anemia
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285275. Online ahead of print.ABSTRACTNot available.PMID:38634143 | DOI:10.3324/haematol.2024.285275 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Matthew P Connor Neeharika Prathapa Noelle V Frey Saar I Gill Elizabeth O Hexner Ximena Jordan Bruno Catherine E Lai Alison W Loren Selina M Luger Andrew H Matthews Shannon R McCurdy Alexander E Perl David L Porter Arlene Zeringue Joseph H Oved Timothy S Source Type: research
Not all central nervous system lymphomas are created equal
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285388. Online ahead of print.ABSTRACTNot available.PMID:38634145 | DOI:10.3324/haematol.2024.285388 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Alvaro J Alencar Juan Pablo Alderuccio Source Type: research
