Not all central nervous system lymphomas are created equal
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285388. Online ahead of print.ABSTRACTNot available.PMID:38634145 | DOI:10.3324/haematol.2024.285388 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Alvaro J Alencar Juan Pablo Alderuccio Source Type: research

Oral iron supplementation: new formulations, old questions
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2024.284967. Online ahead of print.ABSTRACTIron deficiency anemia and pre-anemic iron deficiency are the most frequent pathologies. The first line of treatment involves oral iron supplementation. The simplest, least expensive, and most frequently prescribed drug is ferrous sulfate, while other ferrous salts and ferric complexes with polysaccharides or succinylated milk proteins are also widely used. In recent years, novel iron formulations have been developed, such as the lipophilic iron donor ferric maltol, or nanoparticle encapsulated sucrosomial® iron. Oral iron supplem...
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Kostas Pantopoulos Source Type: research

< em > SH2B3 < /em > alterations in a novel genetic condition, juvenile myelomonocytic leukemia, and myeloproliferative neoplasia
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2023.284747. Online ahead of print.ABSTRACTNot available.PMID:38618667 | DOI:10.3324/haematol.2023.284747 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Charlotte M Niemeyer Miriam Erlacher Source Type: research

Molecular responses in decitabine- and decitabine/venetoclax-treated patients with acute myeloid leukemia and myelodysplastic syndromes
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2022.281396. Online ahead of print.ABSTRACTNot available.PMID:38618679 | DOI:10.3324/haematol.2022.281396 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Agata Gruszczynska Abhishek Maiti Christopher A Miller Sai Mukund Ramakrishnan Daniel C Link Geoffrey L Uy Allegra A Petti Kala Hayes Courtney D DiNardo Farhad Ravandi Timothy J Ley David H Spencer Feng Gao Marina Y Konopleva John S Welch Source Type: research

Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2023.284584. Online ahead of print.ABSTRACTNot available.PMID:38618681 | DOI:10.3324/haematol.2023.284584 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Gregory W Roloff Satyajit Kosuri Mariam T Nawas Adam S DuVall Anand A Patel Peter A Riedell Olatoyosi Odenike Wendy Stock Richard A Larson Michael R Bishop Emma Nunley Lucy A Godley Feighanne Hathaway Daniela Del Gaudio Soma Das Lorraine E Canham Michael Source Type: research

Stem cell factor and erythropoietin-independent production of cultured reticulocytes
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2023.284427. Online ahead of print.ABSTRACTCultured reticulocytes can supplement transfusion needs and offer promise for drug delivery and immune tolerization. They can be produced from induced pluripotent stem cells (iPSCs), but the 45-day culture time and cytokine costs make large-scale production prohibitive. To overcome these limitations, we have generated IPSCs that express constitutive SCF receptor and jak2 adaptor alleles. We show that iPSC lines carrying these alleles can differentiate into self-renewing erythroblast (SRE) that can proliferate for up to 70 cell-doub...
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Emmanuel Olivier Shouping Zhang Zi Yan Eric E Bouhassira Source Type: research

Unfriendly protein of GATA1 and mechanisms of bone marrow failure
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2024.285041. Online ahead of print.ABSTRACTNot available.PMID:38618686 | DOI:10.3324/haematol.2024.285041 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Yigal Dror Source Type: research

Oral iron supplementation: new formulations, old questions
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2024.284967. Online ahead of print.ABSTRACTIron deficiency anemia and pre-anemic iron deficiency are the most frequent pathologies. The first line of treatment involves oral iron supplementation. The simplest, least expensive, and most frequently prescribed drug is ferrous sulfate, while other ferrous salts and ferric complexes with polysaccharides or succinylated milk proteins are also widely used. In recent years, novel iron formulations have been developed, such as the lipophilic iron donor ferric maltol, or nanoparticle encapsulated sucrosomial® iron. Oral iron supplem...
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Kostas Pantopoulos Source Type: research

< em > SH2B3 < /em > alterations in a novel genetic condition, juvenile myelomonocytic leukemia, and myeloproliferative neoplasia
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2023.284747. Online ahead of print.ABSTRACTNot available.PMID:38618667 | DOI:10.3324/haematol.2023.284747 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Charlotte M Niemeyer Miriam Erlacher Source Type: research

Molecular responses in decitabine- and decitabine/venetoclax-treated patients with acute myeloid leukemia and myelodysplastic syndromes
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2022.281396. Online ahead of print.ABSTRACTNot available.PMID:38618679 | DOI:10.3324/haematol.2022.281396 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Agata Gruszczynska Abhishek Maiti Christopher A Miller Sai Mukund Ramakrishnan Daniel C Link Geoffrey L Uy Allegra A Petti Kala Hayes Courtney D DiNardo Farhad Ravandi Timothy J Ley David H Spencer Feng Gao Marina Y Konopleva John S Welch Source Type: research

Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2023.284584. Online ahead of print.ABSTRACTNot available.PMID:38618681 | DOI:10.3324/haematol.2023.284584 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Gregory W Roloff Satyajit Kosuri Mariam T Nawas Adam S DuVall Anand A Patel Peter A Riedell Olatoyosi Odenike Wendy Stock Richard A Larson Michael R Bishop Emma Nunley Lucy A Godley Feighanne Hathaway Daniela Del Gaudio Soma Das Lorraine E Canham Michael Source Type: research

Stem cell factor and erythropoietin-independent production of cultured reticulocytes
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2023.284427. Online ahead of print.ABSTRACTCultured reticulocytes can supplement transfusion needs and offer promise for drug delivery and immune tolerization. They can be produced from induced pluripotent stem cells (iPSCs), but the 45-day culture time and cytokine costs make large-scale production prohibitive. To overcome these limitations, we have generated IPSCs that express constitutive SCF receptor and jak2 adaptor alleles. We show that iPSC lines carrying these alleles can differentiate into self-renewing erythroblast (SRE) that can proliferate for up to 70 cell-doub...
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Emmanuel Olivier Shouping Zhang Zi Yan Eric E Bouhassira Source Type: research

Unfriendly protein of GATA1 and mechanisms of bone marrow failure
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2024.285041. Online ahead of print.ABSTRACTNot available.PMID:38618686 | DOI:10.3324/haematol.2024.285041 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Yigal Dror Source Type: research

Oral iron supplementation: new formulations, old questions
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2024.284967. Online ahead of print.ABSTRACTIron deficiency anemia and pre-anemic iron deficiency are the most frequent pathologies. The first line of treatment involves oral iron supplementation. The simplest, least expensive, and most frequently prescribed drug is ferrous sulfate, while other ferrous salts and ferric complexes with polysaccharides or succinylated milk proteins are also widely used. In recent years, novel iron formulations have been developed, such as the lipophilic iron donor ferric maltol, or nanoparticle encapsulated sucrosomial® iron. Oral iron supplem...
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Kostas Pantopoulos Source Type: research

< em > SH2B3 < /em > alterations in a novel genetic condition, juvenile myelomonocytic leukemia, and myeloproliferative neoplasia
Haematologica. 2024 Apr 11. doi: 10.3324/haematol.2023.284747. Online ahead of print.ABSTRACTNot available.PMID:38618667 | DOI:10.3324/haematol.2023.284747 (Source: Haematologica)
Source: Haematologica - April 15, 2024 Category: Hematology Authors: Charlotte M Niemeyer Miriam Erlacher Source Type: research