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Nutrition: Zinc
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Total 18109 results found since Jan 2013.
Astragaloside IV inhibits pathological functions of gastric cancer-associated fibroblasts through regulation of the HOXA6/ZBTB12 axis
This study aimed to investigate the potential mechanism of astragaloside IV in the regulation of CAF pathological functions in gastric cancer development. Homeobox A6 (HOXA6), and Zinc Finger and BTB Domain Containing 12 (ZBTB12) are highly expressed in gastric CAFs compared with normal fibroblasts (NFs) based on the GSE62740 dataset. We found that astragaloside IV-stimulated CAFs suppressed cell growth, migration, and invasiveness of gastric cancer cells. HOXA6 and ZBTB12 were downregulated after astragaloside IV treatment in CAFs. Further analysis revealed that HOXA6 or ZBTB12 knockdown in CAFs also exerted inhibitory ef...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Haibo Liu Shicheng Luo Xiaofeng Sha Zhiping Chen Dongdong Yang Source Type: research
Protective effect of dietary micronutrients on gastric cancer risk among Jordanians
CONCLUSIONS: our data support favorable effects of dietary consumption of some vitamins and minerals against GC risk.PMID:37705441 | DOI:10.20960/nh.04547
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Sabika Allehdan Shatha S Hammad Razan M Alatrash Tareq Al-Jaberi Ahmad Hushki Shirin Yacoub Mohammad Dahoud Tahra Elobeid Reema Tayyem Tayyem Source Type: research
Zinc intake, SLC30A8 rs3802177 polymorphism, and colorectal cancer risk in a Korean population: a case-control study
CONCLUSIONS: In summary, our findings suggest an inverse association between dietary zinc intake and CRC risk, and this relationship may be modified by SLC30A8 rs3802177 polymorphism.PMID:37707576 | DOI:10.1007/s00432-023-05381-y
Source: Clinical Colorectal Cancer - September 14, 2023 Category: Cancer & Oncology Authors: Linh Thi Dieu Nguyen Madhawa Gunathilake Jeonghee Lee Jae Hwan Oh Hee Jin Chang Dae Kyung Sohn Aesun Shin Jeongseon Kim Source Type: research
Astragaloside IV inhibits pathological functions of gastric cancer-associated fibroblasts through regulation of the HOXA6/ZBTB12 axis
This study aimed to investigate the potential mechanism of astragaloside IV in the regulation of CAF pathological functions in gastric cancer development. Homeobox A6 (HOXA6), and Zinc Finger and BTB Domain Containing 12 (ZBTB12) are highly expressed in gastric CAFs compared with normal fibroblasts (NFs) based on the GSE62740 dataset. We found that astragaloside IV-stimulated CAFs suppressed cell growth, migration, and invasiveness of gastric cancer cells. HOXA6 and ZBTB12 were downregulated after astragaloside IV treatment in CAFs. Further analysis revealed that HOXA6 or ZBTB12 knockdown in CAFs also exerted inhibitory ef...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Haibo Liu Shicheng Luo Xiaofeng Sha Zhiping Chen Dongdong Yang Source Type: research
Bioinspired fabrication of zinc hydroxide-based nanostructure from lignocellulosic biomass Litchi chinensis leaves and its efficacy evaluation on antibacterial, antioxidant, and anticancer activity
In this study, following a low-temperature calcination process, a green synthesis of Zn-hydroxide-based nanostructure has been performed using an aqueous extract derived from the leaves of Litchi chinensis, which is employed as a lignocellulose waste biomass known to possess a variety of phytocompounds. The biogenic preparation of Zn-hydroxide based nanostructures is enabled by bioactive compounds present in the leaf extract, which act as reducing and capping agents. In order to evaluate its physicochemical characteristics, the produced Zn-hydroxide-based nanostructure has been subjected to several characterization techniq...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: Manish Srivastava Kshitij R B Singh Tripti Singh Mohammed Asiri Muath Suliman Haleema Sabia Prakash Ranjan Deen Radha Chaube Jay Singh Source Type: research
A Nanomedicine-Enabled Ion-Exchange Strategy for Enhancing Curcumin-Based Rheumatoid Arthritis Therapy
Angew Chem Int Ed Engl. 2023 Sep 14:e202310061. doi: 10.1002/anie.202310061. Online ahead of print.ABSTRACTCurcumin (Cur) has been clinically used for rheumatoid arthritis treatment by the means of reactive oxygen species (ROS) scavenging and immune microenvironment regulation. However, this compound has a poor water solubility and moderate antioxidative activity, favoring no further broadened application. Metal complexes of curcumin such as zinc-curcumin (Zn-Cur) features enhanced water solubilities, while copper-curcumin (Cu-Cur) shows a higher antioxidant activity but lower solubility than Zn-Cur. Based on their inheren...
Source: Angewandte Chemie - September 14, 2023 Category: Chemistry Authors: Jiacai Yang Bowen Yang Jianlin Shi Source Type: research
Protective effect of dietary micronutrients on gastric cancer risk among Jordanians
CONCLUSIONS: our data support favorable effects of dietary consumption of some vitamins and minerals against GC risk.PMID:37705441 | DOI:10.20960/nh.04547
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Sabika Allehdan Shatha S Hammad Razan M Alatrash Tareq Al-Jaberi Ahmad Hushki Shirin Yacoub Mohammad Dahoud Tahra Elobeid Reema Tayyem Tayyem Source Type: research
Astragaloside IV inhibits pathological functions of gastric cancer-associated fibroblasts through regulation of the HOXA6/ZBTB12 axis
This study aimed to investigate the potential mechanism of astragaloside IV in the regulation of CAF pathological functions in gastric cancer development. Homeobox A6 (HOXA6), and Zinc Finger and BTB Domain Containing 12 (ZBTB12) are highly expressed in gastric CAFs compared with normal fibroblasts (NFs) based on the GSE62740 dataset. We found that astragaloside IV-stimulated CAFs suppressed cell growth, migration, and invasiveness of gastric cancer cells. HOXA6 and ZBTB12 were downregulated after astragaloside IV treatment in CAFs. Further analysis revealed that HOXA6 or ZBTB12 knockdown in CAFs also exerted inhibitory ef...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Haibo Liu Shicheng Luo Xiaofeng Sha Zhiping Chen Dongdong Yang Source Type: research
Protective effect of dietary micronutrients on gastric cancer risk among Jordanians
CONCLUSIONS: our data support favorable effects of dietary consumption of some vitamins and minerals against GC risk.PMID:37705441 | DOI:10.20960/nh.04547
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Sabika Allehdan Shatha S Hammad Razan M Alatrash Tareq Al-Jaberi Ahmad Hushki Shirin Yacoub Mohammad Dahoud Tahra Elobeid Reema Tayyem Tayyem Source Type: research
Bioinspired fabrication of zinc hydroxide-based nanostructure from lignocellulosic biomass Litchi chinensis leaves and its efficacy evaluation on antibacterial, antioxidant, and anticancer activity
In this study, following a low-temperature calcination process, a green synthesis of Zn-hydroxide-based nanostructure has been performed using an aqueous extract derived from the leaves of Litchi chinensis, which is employed as a lignocellulose waste biomass known to possess a variety of phytocompounds. The biogenic preparation of Zn-hydroxide based nanostructures is enabled by bioactive compounds present in the leaf extract, which act as reducing and capping agents. In order to evaluate its physicochemical characteristics, the produced Zn-hydroxide-based nanostructure has been subjected to several characterization techniq...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: Manish Srivastava Kshitij R B Singh Tripti Singh Mohammed Asiri Muath Suliman Haleema Sabia Prakash Ranjan Deen Radha Chaube Jay Singh Source Type: research
