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Condition: Depression

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Total 96548 results found since Jan 2013.

The Combination of Depression and Obesity was Associated with Increased Incidence of Subsequent Total Knee Arthroplasty
CONCLUSION: The incidence of subsequent TKA was greatest for those with the combination of obesity and depression when compared to the Control group and those with individual diagnosis of obesity or depression.PMID:37714551 | DOI:10.3899/jrheum.2023-0367
Source: J Rheumatol - September 15, 2023 Category: Rheumatology Authors: Caitlin E W Conley David C Landy Christian Lattermann Joanne Borg-Stein Jamie E Collins Ana-Maria Vranceanu Cale A Jacobs Source Type: research

Treatment-resistant depression: where to find hope?
World Psychiatry. 2023 Oct;22(3):422-423. doi: 10.1002/wps.21141.NO ABSTRACTPMID:37713550 | PMC:PMC10503916 | DOI:10.1002/wps.21141
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Daniel Souery Source Type: research

Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions
World Psychiatry. 2023 Oct;22(3):394-412. doi: 10.1002/wps.21120.ABSTRACTTreatment-resistant depression (TRD) is common and associated with multiple serious public health implications. A consensus definition of TRD with demonstrated predictive utility in terms of clinical decision-making and health outcomes does not currently exist. Instead, a plethora of definitions have been proposed, which vary significantly in their conceptual framework. The absence of a consensus definition hampers precise estimates of the prevalence of TRD, and also belies efforts to identify risk factors, prevention opportunities, and effective inte...
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Roger S McIntyre Mohammad Alsuwaidan Bernhard T Baune Michael Berk Koen Demyttenaere Joseph F Goldberg Philip Gorwood Roger Ho Siegfried Kasper Sidney H Kennedy Josefina Ly-Uson Rodrigo B Mansur R Hamish McAllister-Williams James W Murrough Charles B Neme Source Type: research

Understanding depression beyond the "mind-body" dichotomy
World Psychiatry. 2023 Oct;22(3):349-350. doi: 10.1002/wps.21142.NO ABSTRACTPMID:37713548 | PMC:PMC10503906 | DOI:10.1002/wps.21142
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Mario Maj Source Type: research

The psychedelic experience and treatment-resistant depression
World Psychiatry. 2023 Oct;22(3):420-422. doi: 10.1002/wps.21140.NO ABSTRACTPMID:37713542 | PMC:PMC10503897 | DOI:10.1002/wps.21140
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Guy M Goodwin Source Type: research

Insomnia Burden among Informal Caregivers of Hospitalized Lung Cancer Patients and Its Influencing Factors
CONCLUSION: Of the hospitalized patients with lung cancer, 51.9% experienced insomnia. Patients' ADL, ICs gender, alcohol consumption, underlying medical conditions, caregiving duration, and monthly expenses were influencing factors. Therefore, prompt screening and early intervention for ICs of patients with lung cancer is necessary.PMID:37711083 | DOI:10.3967/bes2023.099
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Chun Yan Li Yu Jian Song Lan Zhao Mu Hong Deng Rui Xin Li Xiao Ling Zhang Qiong Xuan Li Ying Shi Heng Yu Luan Yuan Yuan Sun Yi Hu Xiao Yong Sai Source Type: research

The challenges of defining and managing treatment-resistant depression in research and practice
World Psychiatry. 2023 Oct;22(3):350-351. doi: 10.1002/wps.21128.NO ABSTRACTPMID:37713579 | PMC:PMC10503900 | DOI:10.1002/wps.21128
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Maurizio Fava Source Type: research

World Health Organization's low-intensity psychosocial interventions: a systematic review and meta-analysis of the effects of Problem Management Plus and Step-by-Step
World Psychiatry. 2023 Oct;22(3):449-462. doi: 10.1002/wps.21129.ABSTRACTMany societies have been recently exposed to humanitarian and health emergencies, which have resulted in a large number of people experiencing significant distress and being at risk to develop mental disorders such as depression, anxiety and post-traumatic stress disorder. The World Health Organization has released a series of scalable psychosocial interventions for people impaired by distress in communities exposed to adversities. Prominent among these is a low-intensity transdiagnostic psychosocial intervention, Problem Management Plus (PM+), and it...
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Sarah K Sch äfer Lea M Thomas Saskia Lindner Klaus Lieb Source Type: research

The ICD-11 opens the door for overdue improved identification of depression in men
World Psychiatry. 2023 Oct;22(3):480-481. doi: 10.1002/wps.21124.NO ABSTRACTPMID:37713575 | PMC:PMC10503896 | DOI:10.1002/wps.21124
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: S øren D Østergaard Zac Seidler Simon Rice Source Type: research

Transdiagnostic risk of mental disorders in offspring of affected parents: a meta-analysis of family high-risk and registry studies
This study demonstrates at a global, meta-analytic level that offspring of affected parents have strongly elevated RR and lifetime risk of developing any mental disorder as well as the same mental disorder diagnosed in the parent. The transdiagnostic risks suggest that offspring of parents with a range of mental disorders should be considered as candidates for targeted primary prevention.PMID:37713573 | PMC:PMC10503921 | DOI:10.1002/wps.21147
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Rudolf Uher Barbara Pavlova Joaquim Radua Umberto Provenzani Sara Najafi Lydia Fortea Maria Ortu ño Anna Nazarova Nader Perroud Lena Palaniyappan Katharina Domschke Samuele Cortese Paul D Arnold Jehannine C Austin Michael M Vanyukov Myrna M Weissman Alla Source Type: research

Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management
World Psychiatry. 2023 Oct;22(3):366-387. doi: 10.1002/wps.21110.ABSTRACTPopulations with common physical diseases - such as cardiovascular diseases, cancer and neurodegenerative disorders - experience substantially higher rates of major depressive disorder (MDD) than the general population. On the other hand, people living with MDD have a greater risk for many physical diseases. This high level of comorbidity is associated with worse outcomes, reduced adherence to treatment, increased mortality, and greater health care utilization and costs. Comorbidity can also result in a range of clinical challenges, such as a more com...
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Michael Berk Ole K öhler-Forsberg Megan Turner Brenda W J H Penninx Anna Wrobel Joseph Firth Amy Loughman Nicola J Reavley John J McGrath Natalie C Momen Oleguer Plana-Ripoll Adrienne O'Neil Dan Siskind Lana J Williams Andre F Carvalho Lianne Schmaal Ada Source Type: research

The lived experience of depression: a bottom-up review co-written by experts by experience and academics
World Psychiatry. 2023 Oct;22(3):352-365. doi: 10.1002/wps.21111.ABSTRACTWe provide here the first bottom-up review of the lived experience of depression, co-written by experts by experience and academics. First-person accounts within and outside the medical field were screened and discussed in collaborative workshops involving numerous individuals with lived experience of depression, family members and carers, representing a global network of organizations. The material was enriched by phenomenologically informed perspectives and shared with all collaborators in a cloud-based system. The subjective world of depression was...
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Paolo Fusar-Poli Andr és Estradé Giovanni Stanghellini Cecilia Maria Esposito Ren é Rosfort Milena Mancini Peter Norman Julieann Cullen Miracle Adesina Gema Benavides Jimenez Caroline da Cunha Lewin Esenam A Drah Marc Julien Muskan Lamba Edwin M Mutura Source Type: research

Cognitive Behaviour Therapy (CBT) for Depersonalization Derealization Disorder (DDD): a self-controlled cross-over study of waiting list vs. active treatment
We report on a clinical audit of 36 participants with a diagnosis of chronic DDD who were sequentially recruited from a specialist DDD National Health Service clinic in London, United Kingdom, and who completed Cognitive Behavioural Therapy specifically adapted for DDD. The sample population had a mean age of 38.7 years (s.d. = 13.4), 61% were male and 69% were of White ethnicity. Three outcomes were assessed (Cambridge Depersonalisation Scale [CDS], Beck Depression Inventory [BDI], and the Beck Anxiety Inventory [BAI]) at three time points in a naturalistic, self-controlled, cross-over design. Hierarchical longitudinal an...
Source: Cognitive Behaviour Therapy - September 15, 2023 Category: Psychiatry & Psychology Authors: Elaine C M Hunter Cheuk Lon Malcolm Wong Rafael Gafoor Glyn Lewis Anthony S David Source Type: research

Role of Minocycline as an Adjunct Neuroinflammatory Modulator in Treatment-Resistant Depression: A Systematic Review of Randomized Controlled Trials
Conclusions: The results were inconsistent regarding the clinical and neuroprotective role of minocycline in TRD. More study is needed to clarify the pathophysiologic and clinical role of minocycline as an immunomodulator in TRD.Prim Care Companion CNS Disord 2023;25(5):22r03467.Author affiliations are listed at the end of this article.PMID:37713730 | DOI:10.4088/PCC.22r03467
Source: The Primary Care Companion for CNS Disorders - September 15, 2023 Category: Primary Care Authors: Wisam Al Jumaili Darshini Vora Chintan Trivedi Shailesh Jain Source Type: research

Efficacy of Low-dose Olanzapine in Combination with Sertraline on Negative Symptoms and Psychosocial Functioning in Schizophrenia: A Randomized Controlled Trial
CONCLUSION: This study demonstrates that low-dose OLA in combination with sertraline had clinically meaningful improvements not only in the negative and depressive symptoms but also in psychosocial functioning in patients with FE-SCH, while not affecting positive symptoms.PMID:37711125 | DOI:10.2174/1570159X21666230913152344
Source: Current Neuropharmacology - September 15, 2023 Category: Drugs & Pharmacology Authors: Meihong Xiu Lei Zhao Qianqian Sun Xiaoe Lang Source Type: research