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Total 1157 results found since Jan 2013.

The Holy Grail: The Search for Undiagnosed Cases Is Paramount in Improving the Cascade of Care Among People Living With HIV.
Abstract Highly Active Antiretroviral Therapy (HAART) has transformed the nature of HIV/AIDS from an imminent death sentence to a chronic manageable condition. There is a growing interest in the potential impact of "treatment as prevention" - a notion that expanded coverage with HAART would substantially reduce morbidity and mortality from HIV, and secondarily HIV transmission at the population level. However, undiagnosed and undocumented HIV cases cannot benefit from HAART and are more likely to experience HIV-related morbidity and untimely mortality. Late diagnosis of HIV remains prevalent and represents missed ...
Source: Canadian Journal of Public Health - November 8, 2013 Category: Global & Universal Authors: Eyawo O, Hogg RS, Montaner JS Tags: Can J Public Health Source Type: research

Africa: The Search for an Effective HIV Vaccine Continues
[The Conversation Africa] An HIV vaccine trial that started in 2016 in South Africa was halted in February 2020. The study sponsors made the call after interim results showed that the vaccine, known as HVTN 702, did not prevent HIV. This result was disappointing, but the search for an effective HIV vaccine continues. Anatoli Kamali speaks to The Conversation Africa's Ina Skosana about other developments in the field.
Source: AllAfrica News: HIV-Aids and STDs - February 17, 2020 Category: Infectious Diseases Source Type: news

The search for an HIV vaccine, the journey continues.
Authors: Dieffenbach CW, Fauci AS PMID: 32418357 [PubMed - in process]
Source: Journal of the International AIDS Society - May 19, 2020 Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research

CNS Summit 2017 Abstracts of Poster Presentations
Conclusion: This novel technology discriminates and quantifies subtle differences in behavior and neurological impairments in subjects afflicted with neurological injury/disease. KINARM assessments can be incorporated into multi-center trials (e.g., monitoring stroke motor recovery: NCT02928393). Further studies will determine if KINARM Labs can demonstrate a clinical effect with fewer subjects over a shorter trial period. Disclosures/funding: Dr. Stephen Scott is the inventor of KINARM and CSO of BKIN Technologies.   Multiplexed mass spectrometry assay identifies neurodegeneration biomarkers in CSF Presenter: Chelsky...
Source: Innovations in Clinical Neuroscience - November 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Drug Development General Genetics Medical Issues Neurology Patient Assessment Psychopharmacology Scales Special Issues Supplements Trial Methodology clinical trials CNS Su Source Type: research

Top 10 Online Medical Resources For The Patients Of The Future
There are over 1 billion health-related searches on Google every single day, according to a report. This was about 7% of all searches on the platform before, and no one will be surprised when the 2020 data massively surpasses this number. After all, the internet is likely the first source to turn to with your health-related questions. But which hits are relevant, and which lead to straightforward la la land – even with the best intentions and the best A.I. toolset, the search giant can’t exclude the latter from among the results. And yet, doing so is especially important in the case of medicine and healthcare, s...
Source: The Medical Futurist - December 10, 2020 Category: Information Technology Authors: berci.mesko Tags: Digital Health Research E-Patients Medical Education Medicine social media Webicina webmd gc2 online resources pharmaceutics Topol Mayo Clinic ePatients Medscape Eric Topol Smart Patients Medline Plus National Library of Source Type: blogs

Expanding Research Capacity in Sub-Saharan Africa Through Informatics, Bioinformatics, and Data Science Training Programs in Mali
Conclusion Bioinformatics and data science training programs in developing countries necessitate incremental and collaborative strategies for their feasible and sustainable development. The progress described here covered decades of collaborative efforts centered on training and research on computationally intensive topics. These efforts laid the groundwork and platforms conducive for hosting a bioinformatics and data science training program in Mali. Training programs are perhaps best facilitated through Africa’s university systems as they are perhaps best positioned to maintain core resources during lapses in sho...
Source: Frontiers in Genetics - April 11, 2019 Category: Genetics & Stem Cells Source Type: research

The Social Science of Covid
By MIKE MAGEE As we enter the third year of the Covid pandemic, with perhaps a partial end in sight, the weight of the debate shows signs of shifting away from genetically engineered therapies, and toward a social science search for historic context. Renowned historian, Charles E. Rosenberg, envisioned a similar transition for the AIDS epidemic in 1989. He described its likely future course then as a “social phenomenon” with these words, “Epidemics start at a moment in time, proceed on a stage limited in space and duration, follow a plot line of increasing and revelatory tension, move to a crisis of individual ...
Source: The Health Care Blog - January 31, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy COVID-19 COVID-19 vaccine Mike Magee vaccines Source Type: blogs

The diversity of the glycan shield of sarbecoviruses related to SARS-CoV-2
Cell Rep. 2023 Mar 15;42(4):112307. doi: 10.1016/j.celrep.2023.112307. Online ahead of print.ABSTRACTAnimal reservoirs of sarbecoviruses represent a significant risk of emergent pandemics, as evidenced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Vaccines remain successful at limiting severe disease and death, but the potential for further coronavirus zoonosis motivates the search for pan-coronavirus vaccines. This necessitates a better understanding of the glycan shields of coronaviruses, which can occlude potential antibody epitopes on spike glycoproteins. Here, we compare the structure o...
Source: IAVI Rep - March 27, 2023 Category: Infectious Diseases Authors: Joel D Allen Dylan P Ivory Sophie Ge Song Wan-Ting He Tazio Capozzola Peter Yong Dennis R Burton Raiees Andrabi Max Crispin Source Type: research