Transient Hematotoxicity After Emerald Horned Pitviper (Ophryacus smaragdinus) Envenomation: A Case Report
In this report, we describe what we believe is the first documented human envenoming from an emerald horned pitviper, Ophryacus smaragdinus.CASE REPORT: A previously healthy 36-year-old woman was bitten on her left index finger by a captive emerald horned pitviper she was medicating at work. Swelling to the entire hand was present on emergency department arrival. She had no systemic symptoms and her initial laboratory studies were unremarkable. The affected limb was elevated. We administered five vials of Antivipmyn TRIⓇ (Bioclon), which specifically lists Ophryacus among the envenomations for which it is indicated. She ...
Source: Pain Physician - May 3, 2024 Category: Anesthesiology Authors: Devin Shumway Karen Pho Nichole Andrews Spencer Greene Source Type: research

Transient Hematotoxicity After Emerald Horned Pitviper (Ophryacus smaragdinus) Envenomation: A Case Report
In this report, we describe what we believe is the first documented human envenoming from an emerald horned pitviper, Ophryacus smaragdinus.CASE REPORT: A previously healthy 36-year-old woman was bitten on her left index finger by a captive emerald horned pitviper she was medicating at work. Swelling to the entire hand was present on emergency department arrival. She had no systemic symptoms and her initial laboratory studies were unremarkable. The affected limb was elevated. We administered five vials of Antivipmyn TRIⓇ (Bioclon), which specifically lists Ophryacus among the envenomations for which it is indicated. She ...
Source: Pain Physician - May 3, 2024 Category: Anesthesiology Authors: Devin Shumway Karen Pho Nichole Andrews Spencer Greene Source Type: research

Effects of diphenhydramine exposure on reproduction of mature Japanese medaka (Oryzias latipes)
In this study, several pairs of mature Japanese medaka (Oryzias latipes) were exposed to DPH for a long period to determine the effects of DPH exposure on the subsequent generations, number of spawned and fertilized eggs, expression of sex-related genes, feeding behavior, embryo development, hatching rate, malformations among the hatched larvae, and mortality rate. The number of spawned eggs significantly decreased, when the parent fish were continuously exposed to 31.6 μg/L DPH for over 46 days. DPH exposure also altered the feeding behavior of medaka individuals, and increased the larval mortality rate. The effects of D...
Source: Chemosphere - May 2, 2024 Category: Chemistry Authors: Tamaki Seki Motoaki Katsura Masatoshi Yamasaki Kazuki Yamashita Emiko Kokushi Seiichi Uno Source Type: research

Effects of diphenhydramine exposure on reproduction of mature Japanese medaka (Oryzias latipes)
In this study, several pairs of mature Japanese medaka (Oryzias latipes) were exposed to DPH for a long period to determine the effects of DPH exposure on the subsequent generations, number of spawned and fertilized eggs, expression of sex-related genes, feeding behavior, embryo development, hatching rate, malformations among the hatched larvae, and mortality rate. The number of spawned eggs significantly decreased, when the parent fish were continuously exposed to 31.6 μg/L DPH for over 46 days. DPH exposure also altered the feeding behavior of medaka individuals, and increased the larval mortality rate. The effects of D...
Source: Chemosphere - May 2, 2024 Category: Chemistry Authors: Tamaki Seki Motoaki Katsura Masatoshi Yamasaki Kazuki Yamashita Emiko Kokushi Seiichi Uno Source Type: research

Effects of diphenhydramine exposure on reproduction of mature Japanese medaka (Oryzias latipes)
In this study, several pairs of mature Japanese medaka (Oryzias latipes) were exposed to DPH for a long period to determine the effects of DPH exposure on the subsequent generations, number of spawned and fertilized eggs, expression of sex-related genes, feeding behavior, embryo development, hatching rate, malformations among the hatched larvae, and mortality rate. The number of spawned eggs significantly decreased, when the parent fish were continuously exposed to 31.6 μg/L DPH for over 46 days. DPH exposure also altered the feeding behavior of medaka individuals, and increased the larval mortality rate. The effects of D...
Source: Chemosphere - May 2, 2024 Category: Chemistry Authors: Tamaki Seki Motoaki Katsura Masatoshi Yamasaki Kazuki Yamashita Emiko Kokushi Seiichi Uno Source Type: research

Effects of diphenhydramine exposure on reproduction of mature Japanese medaka (Oryzias latipes)
In this study, several pairs of mature Japanese medaka (Oryzias latipes) were exposed to DPH for a long period to determine the effects of DPH exposure on the subsequent generations, number of spawned and fertilized eggs, expression of sex-related genes, feeding behavior, embryo development, hatching rate, malformations among the hatched larvae, and mortality rate. The number of spawned eggs significantly decreased, when the parent fish were continuously exposed to 31.6 μg/L DPH for over 46 days. DPH exposure also altered the feeding behavior of medaka individuals, and increased the larval mortality rate. The effects of D...
Source: Chemosphere - May 2, 2024 Category: Chemistry Authors: Tamaki Seki Motoaki Katsura Masatoshi Yamasaki Kazuki Yamashita Emiko Kokushi Seiichi Uno Source Type: research

Comparing the Risk of Infusion-Related Reactions and Tolerability in Patients Given Cetirizine or Diphenhydramine Prior to Ocrelizumab Infusion (PRECEPT)
Conclusions: Overall, our results suggest that cetirizine does not increase the risk of infusion-related reactions compared to diphenhydramine.PMID:38674305 | DOI:10.3390/medicina60040659 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kyle Smoot Horia Marginean Tiffany Gervasi-Follmar Chiayi Chen Source Type: research

Comparing the Risk of Infusion-Related Reactions and Tolerability in Patients Given Cetirizine or Diphenhydramine Prior to Ocrelizumab Infusion (PRECEPT)
Conclusions: Overall, our results suggest that cetirizine does not increase the risk of infusion-related reactions compared to diphenhydramine.PMID:38674305 | PMC:PMC11051876 | DOI:10.3390/medicina60040659 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kyle Smoot Horia Marginean Tiffany Gervasi-Follmar Chiayi Chen Source Type: research

Comparing the Risk of Infusion-Related Reactions and Tolerability in Patients Given Cetirizine or Diphenhydramine Prior to Ocrelizumab Infusion (PRECEPT)
Conclusions: Overall, our results suggest that cetirizine does not increase the risk of infusion-related reactions compared to diphenhydramine.PMID:38674305 | PMC:PMC11051876 | DOI:10.3390/medicina60040659 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kyle Smoot Horia Marginean Tiffany Gervasi-Follmar Chiayi Chen Source Type: research

Comparing the Risk of Infusion-Related Reactions and Tolerability in Patients Given Cetirizine or Diphenhydramine Prior to Ocrelizumab Infusion (PRECEPT)
Conclusions: Overall, our results suggest that cetirizine does not increase the risk of infusion-related reactions compared to diphenhydramine.PMID:38674305 | PMC:PMC11051876 | DOI:10.3390/medicina60040659 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kyle Smoot Horia Marginean Tiffany Gervasi-Follmar Chiayi Chen Source Type: research

Comparing the Risk of Infusion-Related Reactions and Tolerability in Patients Given Cetirizine or Diphenhydramine Prior to Ocrelizumab Infusion (PRECEPT)
Conclusions: Overall, our results suggest that cetirizine does not increase the risk of infusion-related reactions compared to diphenhydramine.PMID:38674305 | PMC:PMC11051876 | DOI:10.3390/medicina60040659 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kyle Smoot Horia Marginean Tiffany Gervasi-Follmar Chiayi Chen Source Type: research

Comparing the Risk of Infusion-Related Reactions and Tolerability in Patients Given Cetirizine or Diphenhydramine Prior to Ocrelizumab Infusion (PRECEPT)
Conclusions: Overall, our results suggest that cetirizine does not increase the risk of infusion-related reactions compared to diphenhydramine.PMID:38674305 | PMC:PMC11051876 | DOI:10.3390/medicina60040659 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kyle Smoot Horia Marginean Tiffany Gervasi-Follmar Chiayi Chen Source Type: research

Comparing the Risk of Infusion-Related Reactions and Tolerability in Patients Given Cetirizine or Diphenhydramine Prior to Ocrelizumab Infusion (PRECEPT)
Conclusions: Overall, our results suggest that cetirizine does not increase the risk of infusion-related reactions compared to diphenhydramine.PMID:38674305 | PMC:PMC11051876 | DOI:10.3390/medicina60040659 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kyle Smoot Horia Marginean Tiffany Gervasi-Follmar Chiayi Chen Source Type: research

Time Savings and Safety of EMS Administration of Antibiotics for Open Fractures
CONCLUSIONS: EMS clinicians were able to safely administer antibiotics to patients with open fractures a median of 15 minutes before arrival at the hospital, and 99 percent of the patients receiving antibiotics had them administered within one hour of EMS dispatch. EMS administration of antibiotics may be a safe way to increase compliance with recommendations for early antibiotic administration for open fractures.PMID:38661320 | DOI:10.1080/10903127.2024.2347291 (Source: Prehospital Emergency Care)
Source: Prehospital Emergency Care - April 25, 2024 Category: Endocrinology Authors: Alexander D Muniz Dominic J Gregorio Scott A Studebaker Aaron M Peth Cole G Camacho Bilie Williams Douglas F Kupas Lawrence H Brown Source Type: research

Time Savings and Safety of EMS Administration of Antibiotics for Open Fractures
CONCLUSIONS: EMS clinicians were able to safely administer antibiotics to patients with open fractures a median of 15 minutes before arrival at the hospital, and 99 percent of the patients receiving antibiotics had them administered within one hour of EMS dispatch. EMS administration of antibiotics may be a safe way to increase compliance with recommendations for early antibiotic administration for open fractures.PMID:38661320 | DOI:10.1080/10903127.2024.2347291 (Source: Rural Remote Health)
Source: Rural Remote Health - April 25, 2024 Category: Rural Health Authors: Alexander D Muniz Dominic J Gregorio Scott A Studebaker Aaron M Peth Cole G Camacho Bilie Williams Douglas F Kupas Lawrence H Brown Source Type: research