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Drug: Nicotine
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Total 8544 results found since Jan 2013.
A core-molecule-shell Au@PATP@Ag nanorod for nicotine detection based on surface-enhanced Raman scattering technology
Anal Chim Acta. 2023 Oct 16;1278:341739. doi: 10.1016/j.aca.2023.341739. Epub 2023 Aug 17.ABSTRACTNicotine is an addictive substance often found in tobacco and cigarette smoke and excessive exposure to it can cause various diseases. Herein, core-molecule-shell gold/4-aminothiophenol/silver nanorods (Au@PATP@Ag NRs) were prepared for quantitative detection of nicotine by using surface-enhanced Raman scattering (SERS) technology. The obtained Au@PATP@Ag NRs showed an outstanding SERS effect due to the plasticity of their morphology and the bimetallic synergistic effect between the excellent stability of Au and the highly enh...
Source: Analytica Chimica Acta - September 14, 2023 Category: Chemistry Authors: Yuhui Chen Yunfei Tang Peng Li Yong Wang Yurong Zhuang Shihao Sun Dingzhong Wang Wei Wei Source Type: research
Demystifying the impact of prenatal tobacco exposure on the placental immune microenvironment: Avoiding the tragedy of mending the fold after death
This study aims to meticulously examine the repercussions of PTE on placental immune landscapes, employing a coordinated research methodology encompassing bioinformatics, machine learning and animal studies. Concurrently, it aims to screen biomarkers and potential compounds that could sensitively indicate and mitigate placental immune disorders. In the course of this research, two gene expression omnibus (GEO) microarrays, namely GSE27272 and GSE7434, were included. Gene set enrichment analysis (GSEA) and immune enrichment investigations on differentially expressed genes (DEGs) indicated that PTE might perturb numerous inn...
Source: J Cell Mol Med - September 13, 2023 Category: Molecular Biology Authors: Xiaoxuan Zhao Yuepeng Jiang Xiao Ma Qujia Yang Xinyi Ding Hanzhi Wang Xintong Yao Linxi Jin Qin Zhang Source Type: research
Exploring Cardiac Impact of Oral Nicotine Exposure in a Transplantable Neoplasm Mice Model: Insights from Biochemical Analysis, Morphometry, and Molecular Docking: Chlorella vulgaris Green Algae Support
This study was designed to investigate the impact of nicotine and Chlorella vulgaris (Ch. V) on cardiac glutathione homeostasis, inflammatory response, cardiac damage markers, apoptotic proteins and histopathological findings in an experimentally transplantable neoplasm mouse model (Ehrlich ascites carcinoma; EAC). In the in-vivo experiment, the female Swiss mice were divided into four groups: control, Ch.V (100mg/kg), Nicotine (100µg/ml/kg), and a combination group ( Nocotine+ Ch.V) for 40 days. Furthermore, the effects of C. vulgaris components on caspase-3, TNF-α, and IL-1β activity were explored using Molecular Oper...
Source: Toxicology - September 13, 2023 Category: Toxicology Authors: Amany Abdel-Rahman Mohamed Gihan G Moustafa Khlood M El Bohy Taghred M Saber Mohamed M M Metwally Heba El Desoukey Mohammed Ali H El-Far Badriyah S Alotaibi Manal Alosaimi Samah S Abuzahrah Leena S Alqahtani Source Type: research
Demystifying the impact of prenatal tobacco exposure on the placental immune microenvironment: Avoiding the tragedy of mending the fold after death
This study aims to meticulously examine the repercussions of PTE on placental immune landscapes, employing a coordinated research methodology encompassing bioinformatics, machine learning and animal studies. Concurrently, it aims to screen biomarkers and potential compounds that could sensitively indicate and mitigate placental immune disorders. In the course of this research, two gene expression omnibus (GEO) microarrays, namely GSE27272 and GSE7434, were included. Gene set enrichment analysis (GSEA) and immune enrichment investigations on differentially expressed genes (DEGs) indicated that PTE might perturb numerous inn...
Source: J Cell Mol Med - September 13, 2023 Category: Molecular Biology Authors: Xiaoxuan Zhao Yuepeng Jiang Xiao Ma Qujia Yang Xinyi Ding Hanzhi Wang Xintong Yao Linxi Jin Qin Zhang Source Type: research
Electronic Cigarette Exposure Disrupts Airway Epithelial Barrier Function and Exacerbates Viral Infection
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00135.2023. Online ahead of print.ABSTRACTThe use of electronic cigarettes (e-cigs), especially among teenagers, has reached alarming and epidemic levels, posing a significant threat to public health. However, the short- and long-term effects of vaping on the airway epithelial barrier are unclear. Airway epithelial cells are the forefront protectors from viruses and pathogens. They contain apical junctional complexes (AJC), which include tight junctions (TJs) and adherens junctions (AJs) formed between adjacent cells. Previously, we reported respiratory ...
Source: Am J Physiol Lung Ce... - September 12, 2023 Category: Respiratory Medicine Authors: Andjela Raduka Nannan Gao Robert L Chatburn Fariba Rezaee Source Type: research
Sex-specific lung inflammation and mitochondrial damage in a model of electronic cigarette exposure in asthma
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00033.2023. Online ahead of print.ABSTRACTThe prevalence of electronic cigarette (EC) use among adult asthmatics has continued to increase over time, in part due to the belief of being less harmful than smoking. However, the extent of their toxicity and the involved mechanisms contributing to the deleterious impact of EC exposure on patients with pre-existing asthma have not been delineated. In the present project, we tested the hypothesis that EC use contributes to respiratory damage and worsening inflammation in the lungs of asthmatics. To define the c...
Source: Am J Physiol Lung Ce... - September 12, 2023 Category: Respiratory Medicine Authors: Min-Ae Song Ji Young Kim Matthew W Gorr Roy A Miller Manjula Karpurapu Jackie Nguyen Devki Patel Kellie J Archer Navjot Pabla Peter G Shields Loren E Wold John W Christman Sangwoon Chung Source Type: research
Electronic Cigarette Exposure Disrupts Airway Epithelial Barrier Function and Exacerbates Viral Infection
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00135.2023. Online ahead of print.ABSTRACTThe use of electronic cigarettes (e-cigs), especially among teenagers, has reached alarming and epidemic levels, posing a significant threat to public health. However, the short- and long-term effects of vaping on the airway epithelial barrier are unclear. Airway epithelial cells are the forefront protectors from viruses and pathogens. They contain apical junctional complexes (AJC), which include tight junctions (TJs) and adherens junctions (AJs) formed between adjacent cells. Previously, we reported respiratory ...
Source: Am J Physiol Lung Ce... - September 12, 2023 Category: Respiratory Medicine Authors: Andjela Raduka Nannan Gao Robert L Chatburn Fariba Rezaee Source Type: research
Sex-specific lung inflammation and mitochondrial damage in a model of electronic cigarette exposure in asthma
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00033.2023. Online ahead of print.ABSTRACTThe prevalence of electronic cigarette (EC) use among adult asthmatics has continued to increase over time, in part due to the belief of being less harmful than smoking. However, the extent of their toxicity and the involved mechanisms contributing to the deleterious impact of EC exposure on patients with pre-existing asthma have not been delineated. In the present project, we tested the hypothesis that EC use contributes to respiratory damage and worsening inflammation in the lungs of asthmatics. To define the c...
Source: Am J Physiol Lung Ce... - September 12, 2023 Category: Respiratory Medicine Authors: Min-Ae Song Ji Young Kim Matthew W Gorr Roy A Miller Manjula Karpurapu Jackie Nguyen Devki Patel Kellie J Archer Navjot Pabla Peter G Shields Loren E Wold John W Christman Sangwoon Chung Source Type: research
Cigarette Smoking Abstinence Among Pregnant Individuals Using E-Cigarettes or Nicotine Replacement Therapy
CONCLUSIONS AND RELEVANCE: These findings suggest that individuals who used e-cigarettes during pregnancy had a higher smoking abstinence rate in late pregnancy than individuals who used NRT, especially for those who initiated e-cigarette use before pregnancy, indicating that replacement of cigarettes with e-cigarettes during pregnancy may be a viable strategy for harm reduction.PMID:37698863 | DOI:10.1001/jamanetworkopen.2023.30249
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Xiaozhong Wen Minseon V Chung Kayla A Liszewski Lauren D Todoro Eve M Giancarlo Wenxin Zhang Sara K Berkelhamer Maciej L Goniewicz Source Type: research
Electronic Cigarette Exposure Disrupts Airway Epithelial Barrier Function and Exacerbates Viral Infection
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00135.2023. Online ahead of print.ABSTRACTThe use of electronic cigarettes (e-cigs), especially among teenagers, has reached alarming and epidemic levels, posing a significant threat to public health. However, the short- and long-term effects of vaping on the airway epithelial barrier are unclear. Airway epithelial cells are the forefront protectors from viruses and pathogens. They contain apical junctional complexes (AJC), which include tight junctions (TJs) and adherens junctions (AJs) formed between adjacent cells. Previously, we reported respiratory ...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - September 12, 2023 Category: Cytology Authors: Andjela Raduka Nannan Gao Robert L Chatburn Fariba Rezaee Source Type: research
Sex-specific lung inflammation and mitochondrial damage in a model of electronic cigarette exposure in asthma
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00033.2023. Online ahead of print.ABSTRACTThe prevalence of electronic cigarette (EC) use among adult asthmatics has continued to increase over time, in part due to the belief of being less harmful than smoking. However, the extent of their toxicity and the involved mechanisms contributing to the deleterious impact of EC exposure on patients with pre-existing asthma have not been delineated. In the present project, we tested the hypothesis that EC use contributes to respiratory damage and worsening inflammation in the lungs of asthmatics. To define the c...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - September 12, 2023 Category: Cytology Authors: Min-Ae Song Ji Young Kim Matthew W Gorr Roy A Miller Manjula Karpurapu Jackie Nguyen Devki Patel Kellie J Archer Navjot Pabla Peter G Shields Loren E Wold John W Christman Sangwoon Chung Source Type: research
Electronic Cigarette Exposure Disrupts Airway Epithelial Barrier Function and Exacerbates Viral Infection
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00135.2023. Online ahead of print.ABSTRACTThe use of electronic cigarettes (e-cigs), especially among teenagers, has reached alarming and epidemic levels, posing a significant threat to public health. However, the short- and long-term effects of vaping on the airway epithelial barrier are unclear. Airway epithelial cells are the forefront protectors from viruses and pathogens. They contain apical junctional complexes (AJC), which include tight junctions (TJs) and adherens junctions (AJs) formed between adjacent cells. Previously, we reported respiratory ...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - September 12, 2023 Category: Cytology Authors: Andjela Raduka Nannan Gao Robert L Chatburn Fariba Rezaee Source Type: research
Sex-specific lung inflammation and mitochondrial damage in a model of electronic cigarette exposure in asthma
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00033.2023. Online ahead of print.ABSTRACTThe prevalence of electronic cigarette (EC) use among adult asthmatics has continued to increase over time, in part due to the belief of being less harmful than smoking. However, the extent of their toxicity and the involved mechanisms contributing to the deleterious impact of EC exposure on patients with pre-existing asthma have not been delineated. In the present project, we tested the hypothesis that EC use contributes to respiratory damage and worsening inflammation in the lungs of asthmatics. To define the c...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - September 12, 2023 Category: Cytology Authors: Min-Ae Song Ji Young Kim Matthew W Gorr Roy A Miller Manjula Karpurapu Jackie Nguyen Devki Patel Kellie J Archer Navjot Pabla Peter G Shields Loren E Wold John W Christman Sangwoon Chung Source Type: research
