Filtered By:
Drug: Aspirin
This page shows you your search results in order of date. This is page number 18.
Order by Relevance | Date
Total 5429 results found since Jan 2013.
Impact of Atrial Fibrillation on Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI): The K-TAVI Registry
CONCLUSION: AF was an independent predictor of 1-year mortality and new pacemaker insertion in Korean patients undergoing TAVI.PMID:37365735 | PMC:PMC10307679 | DOI:10.3349/ymj.2022.0649
Source: Yonsei Medical Journal - June 27, 2023 Category: Universities & Medical Training Authors: Sang Yoon Lee Ki Hong Choi Taek Kyu Park Jihoon Kim Eun Kyoung Kim Sung-Ji Park Seung Woo Park Hyeon-Cheol Gwon Kiyuk Chang Cheol Woong Yu JuHan Kim Young Jin Choi In-Ho Chae Jae-Hwan Lee Jun-Hong Kim Jong Seon Park Won-Jang Kim Young Won Yoon Tae Hoon Ah Source Type: research
DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells
Curr Issues Mol Biol. 2023 May 28;45(6):4665-4674. doi: 10.3390/cimb45060296.ABSTRACTRepositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation to maintain a malignant phenotype, and the mechanistic target of rapamycin (mTORC1) is required for lipogenesis. We, therefore, aimed to test if the expression of mTORC1 suppressor DNA damage-inducible transcript (DDIT4) affects the activity of...
Source: Current Issues in Molecular Biology - June 27, 2023 Category: Molecular Biology Authors: Aist ė Savukaitytė Agn ė Bartnykaitė Justina Bekampyt ė Rasa Ugenskien ė Elona Juozaityt ė Source Type: research
Impact of Atrial Fibrillation on Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI): The K-TAVI Registry
CONCLUSION: AF was an independent predictor of 1-year mortality and new pacemaker insertion in Korean patients undergoing TAVI.PMID:37365735 | PMC:PMC10307679 | DOI:10.3349/ymj.2022.0649
Source: Yonsei Medical Journal - June 27, 2023 Category: Universities & Medical Training Authors: Sang Yoon Lee Ki Hong Choi Taek Kyu Park Jihoon Kim Eun Kyoung Kim Sung-Ji Park Seung Woo Park Hyeon-Cheol Gwon Kiyuk Chang Cheol Woong Yu JuHan Kim Young Jin Choi In-Ho Chae Jae-Hwan Lee Jun-Hong Kim Jong Seon Park Won-Jang Kim Young Won Yoon Tae Hoon Ah Source Type: research
DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells
Curr Issues Mol Biol. 2023 May 28;45(6):4665-4674. doi: 10.3390/cimb45060296.ABSTRACTRepositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation to maintain a malignant phenotype, and the mechanistic target of rapamycin (mTORC1) is required for lipogenesis. We, therefore, aimed to test if the expression of mTORC1 suppressor DNA damage-inducible transcript (DDIT4) affects the activity of...
Source: Current Issues in Molecular Biology - June 27, 2023 Category: Molecular Biology Authors: Aist ė Savukaitytė Agn ė Bartnykaitė Justina Bekampyt ė Rasa Ugenskien ė Elona Juozaityt ė Source Type: research
Impact of Atrial Fibrillation on Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI): The K-TAVI Registry
CONCLUSION: AF was an independent predictor of 1-year mortality and new pacemaker insertion in Korean patients undergoing TAVI.PMID:37365735 | PMC:PMC10307679 | DOI:10.3349/ymj.2022.0649
Source: Yonsei Medical Journal - June 27, 2023 Category: Universities & Medical Training Authors: Sang Yoon Lee Ki Hong Choi Taek Kyu Park Jihoon Kim Eun Kyoung Kim Sung-Ji Park Seung Woo Park Hyeon-Cheol Gwon Kiyuk Chang Cheol Woong Yu JuHan Kim Young Jin Choi In-Ho Chae Jae-Hwan Lee Jun-Hong Kim Jong Seon Park Won-Jang Kim Young Won Yoon Tae Hoon Ah Source Type: research
DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells
Curr Issues Mol Biol. 2023 May 28;45(6):4665-4674. doi: 10.3390/cimb45060296.ABSTRACTRepositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation to maintain a malignant phenotype, and the mechanistic target of rapamycin (mTORC1) is required for lipogenesis. We, therefore, aimed to test if the expression of mTORC1 suppressor DNA damage-inducible transcript (DDIT4) affects the activity of...
Source: Current Issues in Molecular Biology - June 27, 2023 Category: Molecular Biology Authors: Aist ė Savukaitytė Agn ė Bartnykaitė Justina Bekampyt ė Rasa Ugenskien ė Elona Juozaityt ė Source Type: research
Aspirin ameliorates the neurotoxicity of benzoapyrene in mice and HT22 cells: Possible role of miRNA-mRNA network
This study explored the miRNA-mRNA network in the B[a]P-induced neurotoxicity in mice and HT22 cells and the intervention of aspirin (ASP). HT22 cells were treated for 48 h with DMSO, B[a]P (20 μM), or both B[a]P (20 μM) and ASP (4 μM). Following B[a]P treatment, compared to the DMSO controls, HT22 cells showed injured cell morphology, reduced cell viability and neurotrophic factor concentrations, and increased LDH leakage, Aβ1-42, and inflammatory factor concentrations, which were improved by ASP. RNA sequencing and qPCR verified the significant differences of miRNA and mRNA profiles following B[a]P treatment, which w...
Source: Food and Chemical Toxicology - June 26, 2023 Category: Food Science Authors: Jinfeng Zhang Yangyang Li Huan Li Aixiang Liu Jingjing Cao Xin Li Na Xia Zhihong Zhang Jianying Bai Hongmei Zhang Source Type: research
Aspirin Use and Survival Among Patients With Breast Cancer: A Systematic Review and Meta-Analysis
CONCLUSIONS: The only significant association of aspirin with breast cancer outcomes is lower breast-cancer-specific mortality in patients who used aspirin post-diagnostically. However, factors such as selection bias and high inter-study heterogeneity mean that this result should not be treated as conclusive, and more substantial evidence such as that provided by RCTs is needed before any decisions on new clinical uses for aspirin should be made.PMID:37358878 | DOI:10.1093/oncolo/oyad186
Source: The Oncologist - June 26, 2023 Category: Cancer & Oncology Authors: Adam Baker Christiana Kartsonaki Source Type: research
