Filtered By:
Vaccination: Cancer Vaccines
This page shows you your search results in order of date. This is page number 8.
Order by Relevance | Date
Total 7677 results found since Jan 2013.
Advances in immunotherapy for biliary tract cancers
Chin Med J (Engl). 2023 Aug 29. doi: 10.1097/CM9.0000000000002759. Online ahead of print.ABSTRACTBiliary tract cancers (BTC) are a heterogeneous disease with poor prognosis, including gallbladder cancer (GBC), intrahepatic cholangiocarcinoma (ICC), and extrahepatic cholangiocarcinoma (ECC). Although surgery is currently the primary regimen to treat BTC, most BTC patients are diagnosed at an advanced stage and miss the opportunity of surgical eradication. As a result, non-surgical therapy serves as the main intervention for advanced BTC. In recent years, immunotherapy has emerged as the one of the most promising therapies i...
Source: Chinese Medical Journal - August 30, 2023 Category: General Medicine Authors: Yuhao Zhao Mao Yang Jiayi Feng Xu'an Wang Yingbin Liu Source Type: research
Psychometric Validation of the Patient Anal Cancer Knowledge Scale (PACKS) in a Cohort of Black and Hispanic/Latino Sexual and Gender Diverse Young Adults
J Cancer Educ. 2023 Aug 31. doi: 10.1007/s13187-023-02362-0. Online ahead of print.ABSTRACTLack of anal cancer information in priority populations is a major barrier to the uptake and utilization of prevention services. A validated measure of anal cancer knowledge is needed to inform patient education and shared clinical decision-making for anal cancer prevention. The purpose of this study was to validate the Patient Anal Cancer Knowledge Scale (PACKS) in a sample of GBM, namely Black and Hispanic gay, bisexual, and other men who have sex with men (GBM) and gender expansive young adults (aged 18-30 years) living in the USA...
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Christopher W Wheldon Source Type: research
Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer
CONCLUSION: Compared to the Leptin-treated mDC and LPS-treated mDC vaccines, the Leptin/LPS-treated mDC vaccine was more effective in inhibiting BC development and boosting immune responses against tumor.PMID:37647347 | DOI:10.1080/08923973.2023.2253989
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Pedram Basirjafar Raziyeh Zandvakili Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Mahboobeh Vatanparast Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Bahar Naseri Abdollah Jafarzadeh Source Type: research
A unique cytotoxic CD4 < sup > + < /sup > T cell-signature defines critical COVID-19
CONCLUSION: Highly activated and cytotoxic CD4+ T-cell responses may contribute to cell-mediated host tissue damage and progression of COVID-19. Induction of these potentially detrimental T-cell responses should be considered when developing and implementing effective COVID-19 control strategies.PMID:37645435 | PMC:PMC10461786 | DOI:10.1002/cti2.1463
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Sarah Baird Caroline L Ashley Felix Marsh-Wakefield Sibel Alca Thomas M Ashhurst Angela L Ferguson Hannah Lukeman Claudio Counoupas Jeffrey J Post Pamela Konecny Adam Bartlett Marianne Martinello Rowena A Bull Andrew Lloyd Alice Grey Owen Hutchings Umaima Source Type: research
A Comprehensive Review on Current Treatments and Challenges Involved in the Treatment of Ovarian Cancer
In conclusion, tailored nanocarriers would optimize medication delivery into the intracellular compartment before optimizing intra-tumour distribution. Other novel treatment possibilities for ovarian cancer include tumour vaccines, gene therapy, targeting epigenetic alteration, and biologically targeted compounds. These characteristics might enhance the therapeutic efficacy.PMID:37642226 | DOI:10.2174/1568009623666230811093139
Source: Current Cancer Drug Targets - August 29, 2023 Category: Cancer & Oncology Authors: Saika Saman Nimisha Srivastava Mohd Yasir Iti Chauhan Source Type: research
Chemotherapy-induced nanovaccines implement immunogenicity equivalence for improving cancer chemoimmunotherapy
Biomaterials. 2023 Aug 21;301:122290. doi: 10.1016/j.biomaterials.2023.122290. Online ahead of print.ABSTRACTSeveral chemoimmunotherapies have been approved by the FDA for the treatment of various cancers. Chemotherapy has the potential to improve the efficacy of immunotherapy by inducing immunogenic cell death (ICD) of tumor cells, promoting the release of tumor associated antigens (TAAs), tumor specific antigens (TSAs) and damage associated molecular patterns (DAMPs), and disrupting immunosuppressive microenvironments by tumor debulking. Unfortunately, systemic administration of chemotherapeutics carries side effects of ...
Source: Biomaterials - August 29, 2023 Category: Materials Science Authors: Rui Li Yuhao Hao Kyle Roche Guiyuan Chen Wen Pan Andrew Z Wang Yuanzeng Min Source Type: research
Sec22b and Stx4 Depletion Has No Major Effect on Cross-Presentation of PLGA Microsphere-Encapsulated Antigen and a Synthetic Long Peptide In Vitro
This study contributes to characterizing cross-presentation of two promising Ag delivery systems and adds to the discussion about the role of Sec22b/Stx4 in related pathways. Our data point toward SNARE protein redundancy in the cytosolic pathway of cross-presentation.PMID:37638825 | DOI:10.4049/jimmunol.2200473
Source: Journal of Immunology - August 28, 2023 Category: Allergy & Immunology Authors: Emma G M Tondeur Jane S A Voerman Mitchell A A Geleijnse Laure S van Hofwegen Anneloes van Krimpen Julia Koerner Gunja Mishra Ziye Song Christopher Schliehe Source Type: research
Erratum to "Quadrivalent HPV vaccine effectiveness against anogenital warts: A registry-based study of 2,2 million individuals" Vaccine 41(37) (2023) 5469-5476
Vaccine. 2023 Aug 26:S0264-410X(23)01010-1. doi: 10.1016/j.vaccine.2023.08.056. Online ahead of print.NO ABSTRACTPMID:37640570 | DOI:10.1016/j.vaccine.2023.08.056
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: St åle Nygård Mari Nyg ård Madleen Orumaa Bo T Hansen Source Type: research
Poly- γ-glutamic acid nanoparticles as adjuvant and antigen carrier system for cancer vaccination
J Control Release. 2023 Aug 26:S0168-3659(23)00547-3. doi: 10.1016/j.jconrel.2023.08.049. Online ahead of print.ABSTRACTVaccination is an innovative strategy for cancer treatment by leveraging various components of the patients' immunity to boost an anti-tumor immune response. Rationally designed nanoparticles are well suited to maximize cancer vaccination by the inclusion of immune stimulatory adjuvants. Also, nanoparticles might control the pharmacokinetics and destination of the immune potentiating compounds. Poly-γ-glutamic acid (γ-PGA) based nanoparticles (NPs), which have a natural origin, can be easily taken up by...
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Vahideh Mohammadzadeh Niloufar Rahiman Horacio Cabral Sabina Quader Mohammad Reza Zirak Mohammad Ehsan Taghavizadeh Yazdi Mahmoud Reza Jaafari Seyedeh Hoda Alavizadeh Source Type: research
Sec22b and Stx4 Depletion Has No Major Effect on Cross-Presentation of PLGA Microsphere-Encapsulated Antigen and a Synthetic Long Peptide In Vitro
This study contributes to characterizing cross-presentation of two promising Ag delivery systems and adds to the discussion about the role of Sec22b/Stx4 in related pathways. Our data point toward SNARE protein redundancy in the cytosolic pathway of cross-presentation.PMID:37638825 | DOI:10.4049/jimmunol.2200473
Source: Journal of Immunology - August 28, 2023 Category: Allergy & Immunology Authors: Emma G M Tondeur Jane S A Voerman Mitchell A A Geleijnse Laure S van Hofwegen Anneloes van Krimpen Julia Koerner Gunja Mishra Ziye Song Christopher Schliehe Source Type: research
Knowledge, attitudes, concern, behaviors, and barriers associated with the readiness to receive seasonal influenza vaccine among healthcare workers in oncology setting during the COVID-19 pandemic
This study examines the knowledge, attitudes, concerns, behaviors, and barriers related to seasonal influenza vaccination among healthcare workers (HCWs) in the oncology setting during the COVID-19 pandemic. The objective is to assess the readiness of HCWs to receive the influenza vaccine. A cross-sectional study was conducted at the King Hussein Cancer Center (KHCC) in Amman, Jordan. HCWs were surveyed using a self-administered web-based questionnaire between October 2021 and November 2021. Among 223 participants, the coverage rates for seasonal influenza vaccination ranged from 65% to 81% during the autumns of 2019 and 2...
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Sawsan Mubarak Hadeel AlGhawrie Bayan Qaddumi Source Type: research
Creation and characterization of a recombinant mammalian orthoreovirus expressing σ1 fusion proteins encoding human epidermal growth factor receptor 2 peptides
Virology. 2023 Aug 19;587:109871. doi: 10.1016/j.virol.2023.109871. Online ahead of print.ABSTRACTMammalian orthoreovirus (MRV) is an oncolytic virus that has been tested in over 30 clinical trials. Increased clinical success has been achieved when MRV is used in combination with other onco-immunotherapies. This has led the field to explore the creation of recombinant MRVs which incorporate immunotherapeutic sequences into the virus genome. This work focuses on creation and characterization of a recombinant MRV, S1/HER2nhd, which encodes a truncated σ1 protein fused in frame with three human epidermal growth factor recept...
Source: Virology - August 27, 2023 Category: Virology Authors: Nicole A Jandick Cathy L Miller Source Type: research
