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Therapy: Stem Cell Therapy
Vaccination: Covid Vaccine
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Total 121 results found since Jan 2013.
Stem cell-based therapy for COVID-19
Int Immunopharmacol. 2023 Sep 7;124(Pt A):110890. doi: 10.1016/j.intimp.2023.110890. Online ahead of print.ABSTRACTWhile The World Health Organization (WHO) has announced that COVID-19 is no longer a public health emergency of international concern(PHEIC), the risk of reinfection and new emerging variants still makes it crucial to study and work towards the prevention of COVID-19. Stem cell and stem cell-like derivatives have shown some promising results in clinical trials and preclinical studies as an alternative treatment option for the pulmonary illnesses caused by the COVID-19 and can be used as a potential vaccine. In...
Source: International Immunopharmacology - September 9, 2023 Category: Allergy & Immunology Authors: Xiaomei Chen Bowen Liu Chao Li Yulian Wang Suxia Geng Xin Du Jianyu Weng Peilong Lai Source Type: research
Anti-Spike Antibody Responses in Allogeneic Stem Cell Transplant Recipients to Two Doses of COVID-19 mRNA Vaccination: A Retrospective, Single-Center Analysis
J Adv Pract Oncol. 2023 Jul;14(5):367-371. doi: 10.6004/jadpro.2023.14.5.2. Epub 2023 Jul 1.ABSTRACTAllogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients were excluded from the initial SARS-CoV-2 mRNA vaccination efficacy trials. Suboptimal vaccine responses have been reported in immunocompromised cohorts such as patients with solid tumors or hematologic malignancies, suggesting the need for additional research. Widespread data on the antibody responses and vaccine efficacy in allo-HSCT recipients is limited. In our single-center, retrospective study, we analyzed the anti-spike IgG antibody responses in...
Source: Adv Data - August 14, 2023 Category: Epidemiology Authors: Jaime L Shahan Robert H Collins Prapti Patel Yazan F Madanat Madhuri Vusirikala Source Type: research
Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health."
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Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis?
https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/
Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts
Int J Hematol. 2023 Aug 10. doi: 10.1007/s12185-023-03648-1. Online ahead of print.ABSTRACTTo determine the efficacy of SARS-CoV-2 mRNA vaccination for allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients, we measured antibody titer serially in 92 allo-HSCT patients. Among the evaluable 87 patients, median age at vaccination was 53 years (range, 18-75). The average time between allo-HSCT and vaccination was 3.3 years (range, 0.5-15.7). One month after the second dose, 70 patients (80.5%) had a positive response, whereas 17 patients (19.5%) had a negative response (< 20 U/mL). Only patients older tha...
Source: International Journal of Hematology - August 10, 2023 Category: Hematology Authors: Erina Takagi Seitaro Terakura Hidetsugu Fujigaki Akinao Okamoto Kotaro Miyao Masashi Sawa Takanobu Morishita Tatsunori Goto Yukiyasu Ozawa Tetsuya Nishida Nobuaki Fukushima Kazutaka Ozeki Ryo Hanajiri Kuniaki Saito Makoto Murata Akihiro Tomita Hitoshi Kiy Source Type: research
Impaired T-cell response to mRNA vaccination heralds risk of COVID-19 in long-term allogeneic hematopoietic stem cell transplantation survivors
Haematologica. 2023 Aug 3. doi: 10.3324/haematol.2023.283551. Online ahead of print.ABSTRACTNot available.PMID:37534518 | DOI:10.3324/haematol.2023.283551
Source: Haematologica - August 3, 2023 Category: Hematology Authors: Sigrun Einarsdottir Jesper Waldenstr öm Andreas T örnell Johan Ringlander Joakim B Stenb äck Sebastian Malmstr öm Kristoffer Hellstrand Anna Martner Martin Lagging Source Type: research
