Filtered By:
Specialty: Drugs & Pharmacology
Vaccination: Influenza Vaccine
This page shows you your search results in order of date.
Order by Relevance | Date
Total 136 results found since Jan 2013.
Impact of methotrexate treatment on vaccines immunogenicity in adult rheumatological patients - Lessons learned from the COVID-19 pandemic
Biomed Pharmacother. 2023 Aug 3;165:115254. doi: 10.1016/j.biopha.2023.115254. Online ahead of print.ABSTRACTDespite the development of new biological and synthetic targeted therapies, methotrexate remains one of the most commonly used immunomodulatory drugs in rheumatology. However, its effect on the immunogenicity of vaccines has been studied only to a limited extent until recently, resulting in the lack of clear guidelines on the use of methotrexate during vaccination. Significant progress was made during the COVID-19 pandemic due to the dynamic development of research on vaccines, including patients with autoimmune inf...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 5, 2023 Category: Drugs & Pharmacology Authors: Jakub Wro ński Marzena Ciechomska Ewa Kuca-Warnawin Source Type: research
Treatment and prevention of influenza in geriatric patients
Expert Rev Clin Pharmacol. 2023 Aug 1. doi: 10.1080/17512433.2023.2243221. Online ahead of print.ABSTRACTINTRODUCTION: Older adults are the most vulnerable population to the effects of influenza. These patients have age-related characteristics that make response to both infection and therapeutics different than younger patients.AREAS COVERED: Influenza vaccination and antiviral therapy are the foundational approach to preventing and treating influenza in geriatric patients. Older adults should receive one of three enhanced vaccines before influenza season beings. There are five antivirals used in influenza. Geriatric patie...
Source: Pharmacological Reviews - August 1, 2023 Category: Drugs & Pharmacology Authors: Marilyn N Bulloch Source Type: research
Understanding the Global Burden of Influenza in Adults Aged 18 –64 years: A Systematic Literature Review from 2012 to 2022
ConclusionsHigh levels of hospitalization and outpatient visits demonstrated a clinical influenza-associated burden on patients and healthcare systems, which is exacerbated by comorbidities. Considering the size and breadth of the general population aged 18 –64 years, the limited humanistic and economic findings of this SLR likely reflect an underreported burden. Greater investigation into indirect costs and prolonged absenteeism associated with influenza infection is required to fully understand the economic burden in this population.
Source: Advances in Therapy - July 20, 2023 Category: Drugs & Pharmacology Source Type: research
Biomaterial-based delivery platforms for transdermal immunotherapy
Biomed Pharmacother. 2023 Jun 27;165:115048. doi: 10.1016/j.biopha.2023.115048. Online ahead of print.ABSTRACTNowadays, immunotherapy is one of the most essential treatments for various diseases and a broad spectrum of disorders are assumed to be treated by altering the function of the immune system. For this reason, immunotherapy has attracted a great deal of attention and numerous studies on different approaches for immunotherapies have been investigated, using multiple biomaterials and carriers, from nanoparticles (NPs) to microneedles (MNs). In this review, the immunotherapy strategies, biomaterials, devices, and disea...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 29, 2023 Category: Drugs & Pharmacology Authors: Mohammad Dahri Nima Beheshtizadeh Nasrin Seyedpour Amin Nakhostin-Ansari Faezeh Aghajani Simin Seyedpour Moein Masjedi Fatemeh Farjadian Reza Maleki Khosro Adibkia Source Type: research
The disappearance of respiratory syncytial virus and influenza viruses in children during the second year of the COVID-19 pandemic - are non-pharmaceutical interventions as effective as vaccines?
CONCLUSIONS: Influenza and RSV viruses disappeared during the pandemic period and rhinovirus was the second most common virus after the CoVs during and after the restriction period. Non-pharmaceutical interventions should be established as a precaution to prevent infectious diseases even after the pandemic.PMID:37140326 | DOI:10.26355/eurrev_202304_32178
Source: Pharmacological Reviews - May 4, 2023 Category: Drugs & Pharmacology Authors: F M K ışlal Y Hanil çe B Alta ş Z E B üyükbaşaran D G üven Source Type: research
Effect of COVID-19 vaccination on influenza-associated respiratory infection (IARI): benefit or backfire
CONCLUSIONS: It has been challenging to reach any definitive conclusions regarding the effects of C19V on IARI, conducting extensive, substantial population-based studies that integrate clinical and virological data from more than one season is absolutely required, despite the fact that the majority of the reported effects were mild and temporary.PMID:37140325 | DOI:10.26355/eurrev_202304_32175
Source: Pharmacological Reviews - May 4, 2023 Category: Drugs & Pharmacology Authors: P Premalatha H A Shadia M H Abuadas F A Zainab B Prema M A Mervat V Krishnaraju P Kousalya N Harikrishnan M Kandasamy S Pranave Source Type: research
The disappearance of respiratory syncytial virus and influenza viruses in children during the second year of the COVID-19 pandemic - are non-pharmaceutical interventions as effective as vaccines?
CONCLUSIONS: Influenza and RSV viruses disappeared during the pandemic period and rhinovirus was the second most common virus after the CoVs during and after the restriction period. Non-pharmaceutical interventions should be established as a precaution to prevent infectious diseases even after the pandemic.PMID:37140326 | DOI:10.26355/eurrev_202304_32178
Source: Pharmacological Reviews - May 4, 2023 Category: Drugs & Pharmacology Authors: F M K ışlal Y Hanil çe B Alta ş Z E B üyükbaşaran D G üven Source Type: research
Effect of COVID-19 vaccination on influenza-associated respiratory infection (IARI): benefit or backfire
CONCLUSIONS: It has been challenging to reach any definitive conclusions regarding the effects of C19V on IARI, conducting extensive, substantial population-based studies that integrate clinical and virological data from more than one season is absolutely required, despite the fact that the majority of the reported effects were mild and temporary.PMID:37140325 | DOI:10.26355/eurrev_202304_32175
Source: Pharmacological Reviews - May 4, 2023 Category: Drugs & Pharmacology Authors: P Premalatha H A Shadia M H Abuadas F A Zainab B Prema M A Mervat V Krishnaraju P Kousalya N Harikrishnan M Kandasamy S Pranave Source Type: research
Efficacy, effectiveness and safety of the adjuvanted influenza vaccine in the population aged 65 or over
Rev Esp Quimioter. 2023 Apr 20:arrazola20apr2023. doi: 10.37201/req/145.2022. Online ahead of print.ABSTRACTMost of the complications and deaths related to seasonal flu occur in the elderly population (≥65 years) with comorbidities, and the influenza vaccine is the most effective way to prevent them. Immunization is less effective in older adults due to immunosenescence. MF59-adjuvanted vaccines, designed to improve the magnitude, persistence and amplitude of the immune response in elderly people, have been used in clinical practice since 1997 in their trivalent formulation and, since 2020, in their tetravalent formulati...
Source: Revista Espanola de Quimioterapia - April 20, 2023 Category: Drugs & Pharmacology Authors: M P Arrazola Mart ínez J M Eiros Bouza P Plans Rubi ó J Puig-Barber à J Ruiz Arag ón A J Torres Lana Source Type: research
Influenza vaccine is able to prevent neuroinflammation triggered by H7N7 IAV infection
In this study, we investigated the potential effect of vaccination against acute neuroinflammation induced by H7N7 infection and subsequent neuronal damage in the hippocampus, a particularly vulnerable brain region, comparing young and aged mice. Immunosenescence is one of the striking pathophysiological changes during mammalian aging that leads to “inflammaging” and critically limits the protection by vaccines in the elderly. The results suggest that formalin-inactivated H7N7 vaccine has a preventive effect against the inflammatory responses in the periphery and also in the CNS after H7N7 infection. Cytokine and chemo...
Source: Frontiers in Pharmacology - March 29, 2023 Category: Drugs & Pharmacology Source Type: research
High Clinical Burden of Influenza Disease in Adults Aged ≥ 65 Years: Can We Do Better? A Systematic Literature Review
ConclusionsInfluenza exerts a considerable burden on adults aged ≥ 65 years and healthcare systems, with high incidence of hospitalization and mortality. Substantial influenza-associated clinical burden persists despite increasing vaccination coverage among adults aged ≥ 65 years across regions included in this review, which suggests limited effectivene ss of currently available seasonal influenza vaccines. To reduce influenza-associated clinical burden, influenza vaccine effectiveness must be improved. Next generation vaccine production using mRNA technology has demonstrated high effectiveness against another re...
Source: Advances in Therapy - February 15, 2023 Category: Drugs & Pharmacology Source Type: research
