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Specialty: Drugs & Pharmacology
Therapy: Antibiotic Therapy
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Total 588 results found since Jan 2013.
Extracellular Vesicles from Stromal Vascular Fraction of Human Adipose Tissue in the Development of Non-antibiotic Therapy
CONCLUSION: Additionally, the underlying science that explains how the inflammatory process aids in the clearance of infections and the restoration of homeostasis after the host immune system successfully defends against foreign pathogens, as well as the fact that adipose-derived SVF is a noninvasive, cost-effective source of a variety of parent immune cells that produces a good yield of EVs with the same genetic make-up as their parent cells, make this concept worthwhile. This research may thereby increase survival rates and survival quality in cases of resistant infections. Vocabulary: Drug- and cell-free therapy = Nano ...
Source: Current Drug Targets - September 11, 2023 Category: Drugs & Pharmacology Authors: Vani Murthy Halahalli Srinivasa Mohana Kumar Prakash Patil Nikhil Shetty Veena Shetty Source Type: research
Infectious complications among patients receiving ibrutinib for the treatment of hematological malignancies
CONCLUSION: Serious infection and IFI rates are high but similar to those previously described. Risk factors for serious infection included allo-HSCT and corticosteroid use. Targeted antimicrobial prophylaxis should be evaluated in prospective studies in patients on ibrutinib to reduce serious infections and IFI.PMID:37675967 | DOI:10.1093/ajhp/zxad210
Source: American Journal of Health-System Pharmacy : AJHP - September 7, 2023 Category: Drugs & Pharmacology Authors: Kenneth Tham Stacy Prelewicz Sara deHoll Deborah M Stephens Carlos A Gomez Source Type: research
Antimicrobial stewardship program in urinary tract infections due to multiresistant strains in the emergency department
CONCLUSIONS: The implementation of a multidisciplinary program focused on multidrug resistant UTI at discharge form ED correct antibiotic therapy in a large number of patients, being a potentially tool to reduce the number of new ED visits.PMID:37458335 | DOI:10.37201/req/009.2023
Source: Revista Espanola de Quimioterapia - July 17, 2023 Category: Drugs & Pharmacology Authors: J Ruiz-Ramos S Herrera-Mateo M A Rivera-Mart ínez A E Monje-L ópez H Hern ández-Ontiveros C S Pereia-Batista Y M Martinez-Ysasis M Puig-Campmany Source Type: research
Phage Therapy for Diabetic Foot Infection: A Case Series
This article reports the provision of topical adjunctive anti-staphylococcal phage therapy to 10 patients with DFI at high risk of amputation at two UK hospitals as part of clinical care; tolerability and efficacy were clinically assessed.FINDINGS: The opinion of the experienced clinical teams caring for these patients was that 9 of the 10 patients appeared to benefit from adjunctive phage therapy. No adverse effects were reported by clinicians or patients. In 6 of 10 patients the clinical impression was that phage therapy facilitated clinical resolution of infection and limb salvage. Resolution of soft tissue infection wa...
Source: Clinical Therapeutics - July 13, 2023 Category: Drugs & Pharmacology Authors: Matthew J Young Lesley M L Hall Maya Merabishvilli Jean-Paul Pirnay Jason R Clark Joshua D Jones Source Type: research
Consider new therapies for the treatment and prevention of Clostridioides difficile infection
AbstractNew therapies to treat and preventClostridioides difficile infections (CDI) are needed. CDI requires antibiotic therapy, but this can disrupt gut microbiomes and increase susceptibility to recurrent CDI (rCDI). The search for narrow spectrum, microbiome-sparing antibiotics that can eliminate CDI has been challenging. However, three agents are approved for the prevention of rCDI, including the monoclonal antibody bezlotoxumab and two human donor stool products (rectally administered REBYOTATM and oral VOWSTTM).
Source: Drugs and Therapy Perspectives - July 7, 2023 Category: Drugs & Pharmacology Source Type: research
Managing the clinical effects of drug-induced intestinal dysbiosis with a focus to antibiotics: challenges and opportunities
Eur J Pharm Sci. 2023 Jun 26:106510. doi: 10.1016/j.ejps.2023.106510. Online ahead of print.ABSTRACTThe term "intestinal dysbiosis" is used for indicating change(s) of the intestinal microbiota which have been associated with the development of diseases and the deterioration of disease treatments in humans. In this review, documented clinical effects of drug-induced intestinal dysbiosis are briefly presented, and methodologies which could be considered for the management of drug-induced intestinal dysbiosis based on clinical data are critically reviewed. Until relevant methodologies are optimized and/or their effectiveness...
Source: European Journal of Pharmaceutical Sciences - June 28, 2023 Category: Drugs & Pharmacology Authors: Lea Gnatzy George Ismailos Maria Vertzoni Christos Reppas Source Type: research
A Comprehensive Study on Peppermint Oil and Cinnamon Oil as Nanoemulsion: Preparation, Stability, Cytotoxicity, Antimicrobial, Antifungal, and Antioxidant Activity
Conclusion: These findings indicated that the prepared nanoemulsions in the current study might positively influence the dosing regimen and clinical outcomes of antibiotic therapy.PMID:37309758 | DOI:10.2174/1567201820666230612123011
Source: Current Drug Delivery - June 13, 2023 Category: Drugs & Pharmacology Authors: Emrah Özakar Levent Alparslan M Cemal Ad ıgüzel G ülşah Torkay Alper Baran Ay ça Bal-Öztürk Rukiye Sevin ç-Özakar Source Type: research
