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Total 328 results found since Jan 2013.

Understanding Concerns about COVID-19 and Vaccination: Perspectives from Kidney Transplant Recipients
Vaccines (Basel). 2023 Jun 22;11(7):1134. doi: 10.3390/vaccines11071134.ABSTRACTThe COVID-19 pandemic poses a significant risk for immunosuppressed groups such as transplant patients. The purpose of this study was to improve our understanding of the impact of the COVID-19 pandemic on kidney transplant recipients, including their views on COVID-19 vaccination. Semi-structured interviews were conducted from December 2021 to August 2022 with 38 kidney transplant recipients who had an appointment with their transplant care team within the previous 6 months. We used qualitative thematic analysis to characterize the perspectives...
Source: Cancer Control - July 29, 2023 Category: Cancer & Oncology Authors: Sarah R MacEwan Alice A Gaughan Graham N Dixon Ramona G Olvera Willi L Tarver Saurabh Rahurkar Laura J Rush Austin D Schenk Jack Stevens Ann Scheck McAlearney Source Type: research

Kinetics of humoral immune response and severity of infection after three doses of SARS-CoV-2 mRNA vaccine in a large cohort of kidney transplant recipients
CONCLUSIONS: The kinetics of humoral response after three doses of vaccine in kidney transplant patients is characterized by a late but effective immune response against SARS-CoV-2, reducing morbidity and mortality.PMID:37458909 | DOI:10.1007/s40620-023-01650-8
Source: Journal of Nephrology - July 17, 2023 Category: Urology & Nephrology Authors: Simona Simone Francesco Pesce Giulia Font ò Virginia Pronzo Paola Pontrelli Francesca Conserva Annalisa Schirinzi Annalisa Casanova Pasquale Gallo Michele Rossini Giuseppe Lucarelli Marco Spilotros Maria Rendina Giovanni Stallone Francesca Di Serio Alfre Source Type: research

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Immunosuppression regimen modification during COVID-19 infection in kidney transplant recipients
CONCLUSIONS: We found that immunosuppressive regimen minimization did not impact the kidney function in the long-term and it might be a helpful strategy to minimize the effect of COVID-19 infection on patients' condition during the hospital stay. With all the treatments, vaccinations, and precautions, still some patients did not achieve the complete recovery compared to their pre-COVID-19 health status. Fatigue was the main reported symptom amongst all the reported symptoms.PMID:37433396 | DOI:10.1016/j.trim.2023.101883
Source: Transplant Immunology - July 11, 2023 Category: Transplant Surgery Authors: Mahmoudreza Moein Samuel J Martin Carter Whittemore Reeba Thankachan Reut Hod Dvorai Reza F Saidi Source Type: research

SARS-CoV-2 infection: a possible trigger for the recurrence of IgA nephropathy after kidney transplantation?
J Nephrol. 2023 Jun 21. doi: 10.1007/s40620-023-01684-y. Online ahead of print.ABSTRACTImmunoglobulin A nephropathy, the most common primary glomerulonephritis worldwide, is a leading cause of chronic kidney disease and end-stage kidney failure. Several cases of immunoglobulin A nephropathy relapse in native kidneys have been described after COVID-19 vaccination or SARS-CoV-2 infection. Here, we report the case of a 52-year-old kidney transplant recipient who had a stable transplant function for more than 14 years, with a glomerular filtration rate above 30 ml/min/1.73 m2. The patient had been vaccinated against COVID-19 f...
Source: Journal of Nephrology - June 21, 2023 Category: Urology & Nephrology Authors: Eric Jankowski Mandy Schlosser Thorsten Wiech Gunter Wolf Martin Busch Source Type: research

Efficacy and safety of a fourth dose of the COVID-19 vaccine in kidney transplant recipients: A systematic review and meta-analysis
CONCLUSIONS: The fourth dose of the COVID-19 vaccine was well tolerated in KTRs with no serious adverse effects. Some KTRs showed a reduced response even after receiving the fourth vaccine dose. Overall, the fourth vaccine dose effectively improved seropositivity in KTRs, as recommended by the World Health Organization for the general population.PMID:37230397 | PMC:PMC10205136 | DOI:10.1016/j.trim.2023.101864
Source: Transplant Immunology - May 25, 2023 Category: Transplant Surgery Authors: Yasen Kuniduzi Bo Chen Jingjing Zeng Xiaosong Sun Tao Chen Xiaoyuan Qian Jiange Wang Fuchao Liang Rukeya Abuduxukuer Maierhaba Yusufu Shaoyong Xu Xuejun Zhang Source Type: research

The impact of COVID-19 on liver transplantation: challenges and perspectives
Therap Adv Gastroenterol. 2023 May 10;16:17562848231171452. doi: 10.1177/17562848231171452. eCollection 2023.ABSTRACTThe coronavirus disease 2019 (COVID-19) pandemic presented unique challenges to patients with decompensated cirrhosis awaiting transplant, with respect to accessing medical facilities for routine clinic visits, imaging, laboratory workup, or endoscopies. There was a delay in organ procurement that led to a decrease in the number of liver transplants (LTs) and an increase in the morality of waitlisted patients at the beginning of the pandemic. LT numbers later equalized to pre-pandemic numbers due to combined...
Source: Adv Data - May 14, 2023 Category: Epidemiology Authors: Ifrah Fatima Nikki Duong Source Type: research

COVID-19 vaccine acceptance among kidney transplant recipients in Singapore
CONCLUSIONS: Vaccine acceptance rate was high among kidney transplant recipients. Vaccine hesitancy remains a concern in those with a transplant vintage of less than 5 years and those with tertiary educational level. Healthcare provider advocacy is important in improving vaccine acceptance rates.PMID:37171427 | DOI:10.4103/singaporemedj.SMJ-2021-332
Source: Singapore Medical Journal - May 12, 2023 Category: General Medicine Authors: Ian Tatt Liew Hanis Abdul Kadir Sobhana Thangaraju Quan Yao Ho Eleanor Ng Fiona Foo Terence Kee Source Type: research