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Procedure: Liver Transplant
Therapy: Corticosteroid Therapy
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Total 122 results found since Jan 2013.
Association of giant cell hepatitis and autoimmune hemolytic anemia in infancy
Orv Hetil. 2023 Sep 10;164(36):1432-1436. doi: 10.1556/650.2023.32848. Print 2023 Sep 10.ABSTRACTGiant cell hepatitis associated with autoimmune hemolytic anemia (GCH-AIHA) is a rare disorder with unfavorable prognosis, affecting infants and young children. The mortality rate is high, complications of acute liver failure, sepsis, or liver transplantation can be responsible for fatal outcomes. An 18-month-old child who was diagnosed previously with autoimmune hemolytic anemia, developed acute hepatitis and acute liver failure concomitant to the relapse of the disease. GCH-AIHA is characterized by Coombs positive hemolytic a...
Source: Orvosi Hetilap - September 11, 2023 Category: General Medicine Authors: Katalin Csernus Alexandra T észás G ábor Ottóffy Antal Dezs őfi-Gottl Andr ás Tárnok Source Type: research
Alcoholic Hepatitis: The Rising Epidemic
Med Clin North Am. 2023 May;107(3):533-554. doi: 10.1016/j.mcna.2022.12.005. Epub 2023 Feb 20.ABSTRACTAlcoholic hepatitis (AH) is a unique clinical syndrome on the spectrum of alcohol-associated liver disease (ALD). It constitutes a rising epidemic with increasing incidence and major public health implications. In severe AH, 30-day mortality approaches 30%, yet therapeutic options remain limited. Survival benefit from corticosteroids, the mainstay of medical treatment, is short-lived. Among corticosteroid nonresponders, the use of early liver transplantation is heterogeneous across centers and remains limited by significan...
Source: The Medical Clinics of North America - March 31, 2023 Category: General Medicine Authors: Pranav Penninti Ayooluwatomiwa D Adekunle Ashwani K Singal Source Type: research
Engraftment syndrome following Hematopoietic stem cell transplantation: a systematic approach toward diagnosis and management
AbstractEngraftment syndrome (ES) is a non-infectious complication seen both in autologous and allogeneic hematopoietic stem cell transplants and is characterized by the presence of non-infectious fever, diarrhea, skin rash, pulmonary infiltration, pulmonary edema, and deranged renal and liver function tests This review will be delineating the incidence of ES, important differential diagnoses to be considered and management options. The literature search was done through various databases like PubMed, Google scholar, Cochrane library, and EMBASE. The incidence of engraftment syndrome was ranging from 8 to 50% in patients u...
Source: Medical Oncology - December 2, 2022 Category: Cancer & Oncology Source Type: research
CT-347 Acute Graft-Versus-Host Disease: Risk Scoring and Response to Treatment, Experience From Two Centers
CONCLUSIONS: Both scores give complementary information. Minnesota HR and Magic grade IV GVHD patients are less likely to respond to steroids and have higher mortality risks than lower grades.PMID:36164219 | DOI:10.1016/S2152-2650(22)01666-4
Source: Clinical Lymphoma and Myeloma - September 27, 2022 Category: Cancer & Oncology Authors: Maria Silvina Odstrcil Bobillo Mercedes de Jesus Garcia Gonzalo Ariel Ferini Ana Lisa Basquiera Jorge Alberto Arbelbide Georgina Bendek Alberto Gimenez Source Type: research
Clinical features, outcomes, and HLA risk factors associated with nitrofurantoin-induced liver injury
CONCLUSION: NTF-DILI can result in parenchymal necrosis, bridging fibrosis, cirrhosis, and death or liver transplantation, especially with long-term exposure, and is associated with HLA-DRB1*11:04. For mitigating against serious liver injury associated with NTF, the regulators should revise the prescribing information and consider other mitigation strategies.LAY SUMMARY: Liver injury due to nitrofurantoin (NTF) exhibits two patterns: one with short-term exposure and another with long-term exposure. Liver injury due to short-term NTF exposure resembles acute hepatitis, with a low frequency of autoantibodies and benign outco...
Source: Cancer Control - September 24, 2022 Category: Cancer & Oncology Authors: Naga Chalasani Yi-Ju Li Andrew Dellinger Victor Navarro Herbert Bonkovsky Robert J Fontana Jiezhun Gu Huiman Barnhart Elizabeth Phillips Craig Lammert Tae-Hwi Schwantes-An Paola Nicoletti David E Kleiner Jay H Hoofnagle Drug Induced Liver Injury Network Source Type: research
Evaluating the Incidence and Risk Factors for Acute Cellular Rejection in a Steroid Sparing Liver Transplant Center
CONCLUSION AND RELEVANCE: Steroid sparing regimens for IMS post-LT were not associated with an increased incidence of ACR when compared to reported ACR rates in literature. Potential risk factors for ACR include Black race, the use of prednisone maintenance IMS therapy, and CMV viremia.PMID:36004388 | DOI:10.1177/10600280221120059
Source: The Annals of Pharmacotherapy - August 25, 2022 Category: Drugs & Pharmacology Authors: Xunjie Zhang Alicia Lichvar Christine Chan David Choi Source Type: research
