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COVID-19 vaccine-associated myositis: a comprehensive review of the literature driven by a case report
AbstractSeveral cases of vaccine-associated manifestations have been published including cases of inflammatory myositis. Herein, we comprehensively review the literature on the occasion of case of a woman with inflammatory myositis following COVID-19 vaccination. A 67-year-old woman presented with left arm edema, rash, and weakness after the 2nd dose of the BTN162b2 vaccine. Raised muscle enzymes and inflammatory markers with muscle edema on MRI and myositis findings on the electromyogram established the diagnosis. She was successfully treated with methylprednisolone pulses, intravenous immunoglobulin, methotrexate, and hy...
Source: Immunologic Research - August 1, 2023 Category: Allergy & Immunology Source Type: research

Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models. The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Disseminated vaccine-induced varicella infection in a kidney transplant recipient
Am J Transplant. 2023 Jun 5:S1600-6135(23)00522-1. doi: 10.1016/j.ajt.2023.05.034. Online ahead of print.ABSTRACTA 33-year-old kidney transplant (KT) recipient presented with a disseminated pruritic, painful, vesicular rash and hepatitis three weeks after receiving a varicella vaccine (VAR). A skin lesion biopsy sent to the Centers for Disease Control and Prevention (CDC) for genotyping confirmed vaccine-strain varicella-zoster virus (VZV) (Oka strain; vOka). The patient was successfully treated with intravenous acyclovir during a prolonged hospital stay. This case supports the contraindication of VAR in adult KT recipient...
Source: Herpes - June 7, 2023 Category: Infectious Diseases Authors: Megan A Berman Richard E Rupp Source Type: research

Newly diagnosed extranodal NK/T-cell lymphoma, nasal type, at the injected left arm after BNT162b2 mRNA COVID-19 vaccination
Int J Hematol. 2023 Apr 24. doi: 10.1007/s12185-023-03607-w. Online ahead of print.ABSTRACTAnti-SARS-CoV-2 vaccines were developed in response to the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the BNT162b2 mRNA vaccine is effective, adverse effects have been reported. Here, we report a case of extranodal NK/T-cell lymphoma, nasal type (ENKL), of the left arm following BNT162b2 mRNA vaccination. A 73-year-old male presented with a lump in the left arm, which was the site where he received the BNT162b2 mRNA vaccine 3 months prior. He was treat...
Source: International Journal of Hematology - April 24, 2023 Category: Hematology Authors: Takuto Tachita Takenori Takahata Satoru Yamashita Toru Ebina Kosuke Kamata Kazufumi Yamagata Yoshiko Tamai Hirotake Sakuraba Source Type: research

Fight Aging! Newsletter, April 24th 2023
In this study, researchers show that mice lacking a functional ATF4 gene show little to no loss of grip strength and treadmill performance into late life; it is quite an impressive effect size. Assessments of muscle biochemistry do show age-related declines, but to a lesser degree than the controls. How ATF4 knockout functions to produce this outcome is an interesting question. The researchers point out a range of possible downstream and upstream targets that have been implicated in the regulation of muscle growth, but it will clearly require further work to identify the important mechanisms involved. Aging slowly...
Source: Fight Aging! - April 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

COVID-19 vaccine-associated myositis: a comprehensive review of the literature driven by a case report
AbstractSeveral cases of vaccine-associated manifestations have been published including cases of inflammatory myositis. Herein, we comprehensively review the literature on the occasion of case of a woman with inflammatory myositis following COVID-19 vaccination. A 67-year-old woman presented with left arm edema, rash, and weakness after the 2nd dose of the BTN162b2 vaccine. Raised muscle enzymes and inflammatory markers with muscle edema on MRI and myositis findings on the electromyogram established the diagnosis. She was successfully treated with methylprednisolone pulses, intravenous immunoglobulin, methotrexate, and hy...
Source: Immunologic Research - March 16, 2023 Category: Allergy & Immunology Source Type: research

Granuloma annulare after SARS-CoV-2 vaccination: A case report and a literature review
CONCLUSIONS: Clinicians should be aware of the potential, though rare, GA occurrence as a possible adverse event after the SARS-CoV-2 vaccination. This additional case, like what happens after the administration of other vaccines, supports the idea that GA may result from the immune system activation following the vaccination. However, notwithstanding, they should encourage their patients to obtain immunization to assist the public health systems in overcoming the COVID-19 pandemic.PMID:36638589 | PMC:PMC9804962 | DOI:10.1016/j.prp.2022.154300
Source: Pathology, Research and Practice - January 13, 2023 Category: Pathology Authors: Daniela Russo Rossella Accarino Silvia Varricchio Raduan Ahmed Franca Luca Potestio Cataldo Patruno Maddalena Napolitano Massimo Mascolo Source Type: research

Small fiber neuropathy as a complication of SARS-CoV-2 vaccinations
J Family Med Prim Care. 2022 Jul;11(7):4071-4073. doi: 10.4103/jfmpc.jfmpc_2394_21. Epub 2022 Jul 22.ABSTRACTGenerally, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations are not free of side effects. A rarely reported adverse reaction to SARS-CoV-2 vaccinations is small fiber neuropathy (SFN). Here, we present three patients with SFN after the second dose of messenger ribonucleic acid-based SARS-CoV-2 vaccines. Data for this study were collected via the self-made platform "Pubbly" for reporting side effects of SARS-CoV-2 vaccinations. Three patients with post-SARS-CoV-2 vaccination SFN were identifi...
Source: Primary Care - November 17, 2022 Category: Primary Care Authors: Josef Finsterer Source Type: research

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