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Specialty: Biochemistry
Procedure: Dialysis

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Total 206 results found since Jan 2013.

Biobased chitosan-derived self-nitrogen-doped porous carbon nanofibers containing nitrogen-doped zeolites for efficient removal of uremic toxins during hemodialysis
This study provides a novel strategy for transforming chitosan-based materials into state-of-the-art porous carbon nanofiber/zeolite self-N-doped composites, affording an efficient bioderived adsorbent for the removal of uremic toxins in patients with chronic kidney disease.PMID:37709226 | DOI:10.1016/j.ijbiomac.2023.126880
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: I-Hsuan Yang L ászló Szabó Makoto Sasaki Koichiro Uto Joel Henzie Feng-Huei Lin Sadaki Samitsu Mitsuhiro Ebara Source Type: research

Activated carbon derived from wood biochar for Amperometric sensing of Ammonia for early screening of chronic kidney disease
In this study, we have elucidated the functionality and usefulness of a wearable microelectronic research prototype integrated with an HTC-activated carbon @RTIL-based electrochemical sensing platform for detecting ammonia levels released from the skin as a marker for chronic kidney disease screening. By enabling early detection and monitoring, these platforms can facilitate timely interventions, such as lifestyle modifications, medication adjustments, or referral to nephrology specialists. This proactive approach can potentially slow down disease progression, minimize the need for dialysis or transplantation, and ultimate...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: Ivneet Banga Anirban Paul Vikram Narayanan Dhamu Annapoorna Hochihally Ramasubramanya Sriram Muthukumar Shalini Prasad Source Type: research

Biobased chitosan-derived self-nitrogen-doped porous carbon nanofibers containing nitrogen-doped zeolites for efficient removal of uremic toxins during hemodialysis
This study provides a novel strategy for transforming chitosan-based materials into state-of-the-art porous carbon nanofiber/zeolite self-N-doped composites, affording an efficient bioderived adsorbent for the removal of uremic toxins in patients with chronic kidney disease.PMID:37709226 | DOI:10.1016/j.ijbiomac.2023.126880
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: I-Hsuan Yang L ászló Szabó Makoto Sasaki Koichiro Uto Joel Henzie Feng-Huei Lin Sadaki Samitsu Mitsuhiro Ebara Source Type: research

Activated carbon derived from wood biochar for Amperometric sensing of Ammonia for early screening of chronic kidney disease
In this study, we have elucidated the functionality and usefulness of a wearable microelectronic research prototype integrated with an HTC-activated carbon @RTIL-based electrochemical sensing platform for detecting ammonia levels released from the skin as a marker for chronic kidney disease screening. By enabling early detection and monitoring, these platforms can facilitate timely interventions, such as lifestyle modifications, medication adjustments, or referral to nephrology specialists. This proactive approach can potentially slow down disease progression, minimize the need for dialysis or transplantation, and ultimate...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: Ivneet Banga Anirban Paul Vikram Narayanan Dhamu Annapoorna Hochihally Ramasubramanya Sriram Muthukumar Shalini Prasad Source Type: research

Encapsulation of Dicranopteris linearis extract using cellulose microparticles for antiulcer medication
Int J Biol Macromol. 2023 Sep 7:126795. doi: 10.1016/j.ijbiomac.2023.126795. Online ahead of print.ABSTRACTDicranopteris linearis (DL) is a fern in the Gleicheniaceae family, locally known as resam by the Malay community. It has numerous pharmacological benefits, with antiulcer and gastroprotective properties. Peptic ulcer is a chronic and recurring disease that significantly impacts morbidity and mortality, affecting nearly 20 % of the world's population. Despite the effectiveness of peptic ulcer drugs, there is no perfect treatment for the ailment. Encapsulation is an advanced technique that can treat peptic ulcers by in...
Source: International Journal of Biological Macromolecules - September 9, 2023 Category: Biochemistry Authors: Anis Adilah Ahmad Khairul Farihan Kasim Subash C B Gopinath Periasamy Anbu Noor Soffalina Sofian Seng Source Type: research

Small conformational changes in IgG1 detected as acidic charge variants by cation exchange chromatography
This study provides new insights into the characterization of acidic variants that are currently not fully understood.PMID:37652129 | DOI:10.1016/j.ab.2023.115302
Source: Analytical Biochemistry - August 31, 2023 Category: Biochemistry Authors: Masakazu Fukuda Melissa A Graewert Cy M Jeffries Dmitri I Svergun Tadao Yamazaki Akiko Koga Yuji Yamanaka Source Type: research

Precision engineered peptide targeting leukocyte extracellular traps mitigate acute kidney injury in Crush syndrome
In conclusion, we developed a novel medium-molecular-weight peptide that could potentially treat patients with rhabdomyolysis and protect their renal function, thereby increasing the survival rate of victims affected by Crush syndrome.PMID:37302292 | DOI:10.1016/j.bbrc.2023.06.013
Source: Biochemical and Biophysical Research communications - June 11, 2023 Category: Biochemistry Authors: Koshu Okubo Kentaro Takayama Hiroshi Kawakami Kiriko Iida Hiroaki Miyauchi Yoshimi Roppongi Hiroaki Ikeyama Matsuhiko Hayashi Seitaro Fujishima Junichi Sasaki Junji Haruta Yoshio Hayashi Junichi Hirahashi Source Type: research

Polyamidoamine Dendrimers Functionalized with ZnO-Chitosan Nanoparticles as an Efficient Surface for L-asparaginase Immobilization
In this study, the third-generation polyamidoamine dendrimer was functionalized with a 5-amino-1H-tetrazole heterocycle to load the synthesis enzyme and its surface groups. Then, chitosan was attached to the dendrimer by a suitable linker, and finally, zinc oxide nanoparticles were inserted into dendrimer cavities to increase loading. FTIR, FESEM, TEM, and DLS analysis showed that this new dendrimer has specific branches, and ZnO nanoparticles were spread between the branches and connected with the branches and chitosan biopolymer. Also proved the presence of stabilized L-asparaginase enzyme and ZnO nanoparticles in the de...
Source: Applied Biochemistry and Biotechnology - June 7, 2023 Category: Biochemistry Authors: Sudabeh Iraninasab Ahmad Homaei Elaheh Mosaddegh Masoud Torkzadeh-Mahani Source Type: research

Complete Genome Sequencing and Bacteriocin Functional Characterization of Pediococcus ethanolidurans CP201 from Daqu
In conclusion, the bacteriocin produced by the newly isolated CP201 can be applied to the preservation of meat products to prevent the risk of food-borne diseases.PMID:37285000 | DOI:10.1007/s12010-023-04575-x
Source: Applied Biochemistry and Biotechnology - June 7, 2023 Category: Biochemistry Authors: Tongwei Guan Liuzhu Long Ying Liu Lei Tian Zhong Peng Zongjun He Source Type: research

Nephro-oncology: clinical and biochemical aspects of kidney disease and cancer
This article focuses on acute kidney injury (AKI), chronic kidney disease (CKD), various electrolyte and acid-base disorders, the most common cancers after kidney transplantation and the kidney disorders associated with HSCT (hematopoietic stem cell transplantation). The possibility of the application of novel cancer therapy, such as cancer immunotherapy and proton therapy in transplant recipients was also discussed.PMID:37159995 | DOI:10.18388/abp.2020_6588
Source: Acta Biochim Pol - May 9, 2023 Category: Biochemistry Authors: Slawomir Lizakowski Alicja D ębska-Ślizień Ilona Kurnatowska Maciej Jan Zaucha Marcin Matuszewski Beata Naumnik Marcin Adamczak Jerzy Chudek Magdalena Durlik Carla Ferr ándiz-Pulido Bartosz Foroncewicz Ryszard Gellert Magdalena Krajewska Micha ł Nowi Source Type: research

Ex vivo hemolysis: three cases demonstrating mechanically-induced hemolysis from the extracorporeal circuit during hemodialysis
Clin Biochem. 2023 May 3:S0009-9120(23)00081-4. doi: 10.1016/j.clinbiochem.2023.04.009. Online ahead of print.ABSTRACTSporadic mechanically-induced hemolysis associated with kinks in extracorporeal blood circuits during hemodialysis is a rare but potentially serious complication that exhibits laboratory features consistent with both in vivo and in vitro hemolysis. Misclassification of clinically significant hemolysis as in vitro can lead to inappropriate test cancellation and delayed medical interventions. Here, we report three cases of hemolysis attributed to kinked hemodialysis blood lines, which we have defined as "ex v...
Source: Clinical Biochemistry - May 5, 2023 Category: Biochemistry Authors: Ashley M Newbigging Raymond Xing Branko Braam Joshua E Raizman Source Type: research

Chlorhexidine digluconate exerts bactericidal activity vs Gram positive Staphylococci with bioelectrocatalytic compatibility: High level disinfection for implantable biofuel cells
Bioelectrochemistry. 2023 Apr 5;152:108435. doi: 10.1016/j.bioelechem.2023.108435. Online ahead of print.ABSTRACTImplanted devices destined for contact with sterile body tissues, vasculature or fluids should be free of any microbial contamination that could lead to disease transmission. The disinfection and sterilisation of implantable biofuel cells is a challenging and largely overlooked subject due to the incompatibility of fragile biocatalytic components with classical treatments. Here we report the development of a convenient "soft" chemical treatment based on immersion of enzymatic bioelectrodes and biofuel cells in d...
Source: Bioelectrochemistry - April 26, 2023 Category: Biochemistry Authors: Anastasiia Berezovska Anne Meiller St éphane Marinesco Yannig Nedellec Fabien Giroud Andrew J Gross Serge Cosnier Source Type: research