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Specialty: Cancer & Oncology
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Total 157562 results found since Jan 2013.
Abstract 2719: TCRP1 gene promotes NIH/3T3 cell transformation by over-activating PDPK1 and Akt
This study was supported by grant from National Natural Science Foundation (81472184) of China.}Citation Format: Chengkun Wang, Xiaorong Liu, Qinwei Qiu, Zhijie Zhang, Jiang Yin, Guopei Zheng, Zhimin He. TCRP1 gene promotes NIH/3T3 cell transformation by over-activating PDPK1 and Akt. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 2719. doi:10.1158/1538-7445.AM2015-2719
Source: Cancer Research - August 2, 2015 Category: Cancer & Oncology Authors: Wang, C., Liu, X., Qiu, Q., Zhang, Z., Yin, J., Zheng, G., He, Z. Tags: Carcinogenesis Source Type: research
Cancers, Vol. 14, Pages 118: Percutaneous Hepatic Perfusion (PHP) with Melphalan in Liver-Dominant Metastatic Uveal Melanoma: The German Experience
In conclusion, PHP is a safe and effective salvage treatment for liver-dominant metastatic uveal melanoma. Serious AEs—though rare—demand careful patient selection.
Source: Cancers - December 27, 2021 Category: Cancer & Oncology Authors: Cornelia L. A. Dewald Mia-Maria Warnke Roland Br üning Martin A. Schneider Peter Wohlmuth Jan B. Hinrichs Anna Saborowski Arndt Vogel Frank K. Wacker Tags: Article Source Type: research
Deep Learning and Machine Learning with Grid Search to Predict Later Occurrence of Breast Cancer Metastasis Using Clinical Data
CONCLUSIONS: Our results show that deep learning with grid search overall performs at least as well as other machine learning methods when using non-image clinical data. It is interesting to note that some of the other machine learning methods, such as XGB, RF, and SVM, are very strong competitors of DFNN when incorporating grid search. It is also worth noting that the computation time required to do grid search with DFNN is much more than that required to do grid search with the other nine machine learning methods.PMID:36233640 | DOI:10.3390/jcm11195772
Source: Clinical Breast Cancer - October 14, 2022 Category: Cancer & Oncology Authors: Xia Jiang Chuhan Xu Source Type: research
Readability Analysis of Online Breast Cancer Surgery Patient Education Materials from National Cancer Institute-Designated Cancer Centers Compared with Top Internet Search Results
CONCLUSIONS: Patient education materials on breast cancer from both NCI-DCC and top Internet search results were written several reading grade levels higher than the NIH recommendation. Materials should be revised to enhance patient comprehension of breast cancer surgical treatment and guide patients in this important decision-making process to ultimately improve health outcomes.PMID:37707665 | DOI:10.1245/s10434-023-14279-5
Source: Ann Oncol - September 14, 2023 Category: Cancer & Oncology Authors: Anna Rauzi Lauren E Powell McKenzie White Saranya Prathibha Jane Yuet Ching Hui Source Type: research
Lessons from a systematic literature search on diagnostic DNA methylation biomarkers for colorectal cancer: how to increase research value and decrease research waste
DiscussionThis systematic literature search revealed that major requirements to develop clinically relevant diagnostic CRC DNA methylation markers are often lacking. To avoid the resulting research waste, clinical needs, intended biomarker use and independent validation should be better considered prior to study design. In addition, improved reporting quality would facilitate meta-analysis, thereby increasing level of evidence and enabling clinical translation.PMID:35584320 | DOI:10.14309/ctg.0000000000000499
Source: Clinical Colorectal Cancer - May 18, 2022 Category: Cancer & Oncology Authors: Zheng Feng Cary J G Oberije Alouisa J P van de Wetering Alexander Koch Kim A D Wouters Nathalie Vaes Ad A M Masclee Beatriz Carvalho Gerrit A Meijer Maurice P Zeegers James G Herman Veerle Melotte Manon van Engeland Kim M Smits Source Type: research
Zoom behavior during visual search modulates pupil diameter and reflects adaptive control states
This study tested predictions of this theory in the context of a societally important visual search task: the review and interpretation of digital whole slide images of breast biopsies by physicians (pathologists). As these medical images are searched, pathologists encounter difficult visual features and intermittently zoom in to examine features of interest. We propose that tonic and phasic pupil diameter changes during image review may correspond to perceived difficulty and dynamic shifts between exploration and exploitation control states. To examine this possibility, we monitored visual search behavior and tonic and ph...
Source: Cancer Control - March 9, 2023 Category: Cancer & Oncology Authors: Tad T Bruny é Trafton Drew Kathleen F Kerr Hannah Shucard Kate Powell Donald L Weaver Joann G Elmore Source Type: research
Search Term Identification Methods for Computational Health Communication: Word Embedding and Network Approach for Health Content on YouTube
CONCLUSIONS: We demonstrated a retrieval technique to improve recall and minimize precision loss, which can be extended to various health topics on YouTube, a popular video-sharing social media platform. We discussed how health communication scholars can apply the technique to inspect the performance of the retrieval strategy before investing human coding resources and outlined suggestions on how such a technique can be extended to other health contexts.PMID:36040760 | DOI:10.2196/37862
Source: Cancer Control - August 30, 2022 Category: Cancer & Oncology Authors: Chau Tong Drew Margolin Rumi Chunara Jeff Niederdeppe Teairah Taylor Natalie Dunbar Andy J King Source Type: research
Yoga for chronic non-specific low back pain
CONCLUSIONS: There is low- to moderate-certainty evidence that yoga compared to no exercise results in small and clinically unimportant improvements in back-related function and pain. There is probably little or no difference between yoga and other back-related exercise for back-related function at three months, although it remains uncertain whether there is any difference between yoga and other exercise for pain and quality of life. Yoga is associated with more adverse events than no exercise, but may have the same risk of adverse events as other exercise. In light of these results, decisions to use yoga instead of no exe...
Source: Cancer Control - November 18, 2022 Category: Cancer & Oncology Authors: L Susan Wieland Nicole Skoetz Karen Pilkington Shireen Harbin Ramaprabhu Vempati Brian M Berman Source Type: research
Hyperbaric oxygen therapy for late radiation tissue injury
CONCLUSIONS: These small studies suggest that for people with LRTI affecting tissues of the head, neck, bladder and rectum, HBOT may be associated with improved outcomes (low- to moderate-certainty evidence). HBOT may also result in a reduced risk of wound dehiscence and a modest reduction in pain following head and neck irradiation. However, HBOT is unlikely to influence the risk of death in the short term. HBOT also carries a risk of adverse events, including an increased risk of a reduction in visual acuity (usually temporary) and of ear barotrauma on compression. Hence, the application of HBOT to selected participants ...
Source: Cancer Control - August 16, 2023 Category: Cancer & Oncology Authors: Zhiliang Caleb Lin Michael H Bennett Glen C Hawkins Charles Paul Azzopardi John Feldmeier Robert Smee Christopher Milross Source Type: research
Platinum-based chemotherapy for early triple-negative breast cancer
CONCLUSIONS: Platinum-based chemotherapy using carboplatin in the adjuvant or neoadjuvant setting improves long-term outcomes of DFS and OS in early TNBC, with no evidence of differences by subgroup. This was at the cost of more frequent chemotherapy delays and dose reductions, and greater haematological toxicity, though serious adverse events including neuropathy, febrile neutropenia or treatment-related death were not increased. These findings support the use of platinum-based chemotherapy for people with early TNBC. The optimal dose and regimen are not defined by this analysis, but there is a suggestion that similar rel...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Sofia Re Mason Melina L Willson Sam J Egger Jane Beith Rachel F Dear Annabel Goodwin Source Type: research
