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Specialty: Urology & Nephrology

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Total 98061 results found since Jan 2013.

First postoperative PSA is associated with outcomes in patients with node positive prostate cancer: Results from the SEARCH database.
CONCLUSIONS: pN1 patients with a first postoperative PSA ≥0.2ng/ml were more likely to develop metastases. First postoperative PSA may be useful in identifying pN1 patients who harbor distant disease and aid in secondary treatment decisions. PMID: 29429895 [PubMed - as supplied by publisher]
Source: Urologic Oncology - February 8, 2018 Category: Urology & Nephrology Authors: McDonald ML, Howard LE, Aronson WJ, Terris MK, Cooperberg MR, Amling CL, Freedland SJ, Kane CJ Tags: Urol Oncol Source Type: research

Radical Prostatectomy and the Effect of Close Surgical Margins: Results from the SEARCH database
ConclusionsManagement of men with close surgical margins is a diagnostic challenge, with a disease course that is not entirely benign. Evaluation of other known risk factors likely provide greater prognostic value for these men and may ultimately better select those who may benefit from adjuvant therapy.This article is protected by copyright. All rights reserved.
Source: BJU International - February 1, 2018 Category: Urology & Nephrology Authors: Christine Herforth, Sean P. Stroup, Zinan Chen, Lauren E. Howard, Stephen J. Freedland, Daniel M. Moreira, Martha K. Terris, William J. Aronson, Matthew R. Cooperberg, Christopher L. Amling, Christopher J. Kane Tags: Original Article Source Type: research

Socioeconomic status, race, and long-term outcomes after radical prostatectomy in an equal access health system: Results from the SEARCH database.
CONCLUSIONS: In an equal-access setting, lower SES associated with decreased CRPC, metastases, and PCSM in black but not white men. If confirmed, these findings suggest a complex relationship between race, SES, and PC with further research needed to understand why low SES in black men decreased the risk for poor PC outcomes after RP. PMID: 30598238 [PubMed - as supplied by publisher]
Source: Urologic Oncology - December 28, 2018 Category: Urology & Nephrology Authors: Everist MM, Howard LE, Aronson WJ, Kane CJ, Amling CL, Cooperberg MR, Terris MK, Freedland SJ Tags: Urol Oncol Source Type: research

In Search for risk predictors at the microscopic scenario of a negative biopsy. A systematic review
ConclusionsThe MS of a negative PB may include atypical small acinar proliferation, HGPIN, prostatic atrophy, inflammatory proliferative atrophy and prostatic inflammation lesions, since they all seem to be associated with the risk of PC detection in repeat PB. This review has led us to create the hypothesis that the MS of a negative PB might be a valuable and useful tool when considering repeat PB.ResumenIntroducciónLas biopsias prostáticas (BP) de repetición, ante la persistencia de la sospecha de cáncer de próstata (CP), son frecuentes y su rendimiento bajo. En el contexto de una BP negativa existe un escenario mic...
Source: Actas Urologicas Espanolas - July 27, 2019 Category: Urology & Nephrology Source Type: research

Derivation and validation of text search algorithms for renal and adrenal lesion identification in radiology text reports.
CONCLUSIONS: Textual radiology reports can be analyzed using common statistical software to accurately determine the probability that important abnormalities of the kidneys or adrenal glands exist. These methods can be used for case identification or epidemiological studies. PMID: 31977309 [PubMed - as supplied by publisher]
Source: Canadian Urological Association Journal - January 19, 2020 Category: Urology & Nephrology Authors: Lavallée LT, Knee C, Ross J, Lau JL, Mookerji N, van Walraven C Tags: Can Urol Assoc J Source Type: research

Invited Submission/Authors ’ Reply To: "It's All Relative: Assessing Online Search Interest in Genitourinary Cancer Awareness Campaigns" (#URL-D-20-00418)
Google Trends offers a novel method of evaluating interest in particular topics but certainly must be used with caution. As outlined in the accompanying letter to the editor, there are several limitations that must be taken into consideration. Demographics of those searching for a particular topic cannot be distinguished, which is a critical component to understanding search patterns. In addition, search terminology necessarily restricts the results in a manner that could potentially bias the trends.
Source: Urology - April 14, 2020 Category: Urology & Nephrology Authors: Mehul S. Patel, Joshua A. Halpern, Anuj S. Desai, Mary K. Keeter, Nelson E. Bennett, Robert E. Brannigan Tags: Letter to the Editor Source Type: research

Authors ’ Reply to: “It's All Relative: Assessing Online Search Interest in Genitourinary Cancer Awareness Campaigns” (#URL-D-20-00418)
Google Trends offers a novel method of evaluating interest in particular topics but certainly must be used with caution. As outlined in the accompanying letter to the editor, there are several limitations that must be taken into consideration. Demographics of those searching for a particular topic cannot be distinguished, which is a critical component to understanding search patterns. In addition, search terminology necessarily restricts the results in a manner that could potentially bias the trends.
Source: Urology - April 14, 2020 Category: Urology & Nephrology Authors: Mehul S. Patel, Joshua A. Halpern, Anuj S. Desai, Mary K. Keeter, Nelson E. Bennett, Robert E. Brannigan Tags: Letter to the Editor Source Type: research

Diabetes predicts metastasis after radical prostatectomy in obese men: results from the SEARCH database
Conclusions Diabetes was not associated with metastasis risk overall. Stratification by obesity yielded significant differences, with diabetes linked to a fourfold higher metastasis risk in obese men, despite predicting more aggressive secondary treatment. Longer diabetes duration was also associated with increased metastasis risk.
Source: BJU International - January 10, 2013 Category: Urology & Nephrology Authors: Chenwei Wu, William J. Aronson, Martha K. Terris, Joseph C. Presti, Christopher J. Kane, Christopher L. Amling, Stephen J. Freedland Tags: Urological Oncology Source Type: research

Metformin does not affect risk of biochemical recurrence following radical prostatectomy: results from the SEARCH database
rman & S J Freedland
Source: Prostate Cancer and Prostatic Diseases - October 8, 2013 Category: Urology & Nephrology Authors: E H AllottM R AbernL GerberC J KetoW J AronsonM K TerrisC J KaneC L AmlingM R CooperbergP G MoormanS J Freedland Tags: metformin diabetes biochemical recurrence outcomes Source Type: research

Predicting bone scan positivity after biochemical recurrence following radical prostatectomy in both hormone-naive men and patients receiving androgen-deprivation therapy: results from the SEARCH database
& S J Freedland
Source: Prostate Cancer and Prostatic Diseases - January 14, 2014 Category: Urology & Nephrology Authors: D M MoreiraM R CooperbergL E HowardW J AronsonC J KaneM K TerrisC L AmlingM KuchibhatlaS J Freedland Tags: disease-free survival metastasis mortality prostatectomy PSA Source Type: research

Postoperative statin use and risk of biochemical recurrence following radical prostatectomy: Results from the SEARCH database
ConclusionIn this retrospective cohort of men undergoing RP, postoperative statin use was significantly associated with reduced risk of BCR.Whether the association between postoperative statin use and BCR differs by race requires further study.Given these findings, coupled with other studies suggesting that statins may reduce risk of advanced PC, randomized controlled trials are warranted to formally test the hypothesis that statins slow PC progression.
Source: BJU International - March 3, 2014 Category: Urology & Nephrology Authors: Emma H. Allott, Lauren E. Howard, Matthew R. Cooperberg, Christopher J. Kane, William J. Aronson, Martha K. Terris, Christopher L. Amling, Stephen J. Freedland Tags: Urological Oncology Source Type: research

The Role of Information Technology (Apps) in FPMRS
The objective of this study is to provide a comprehensive overview of the use of smartphone “apps” within the field of female pelvic medicine and reconstructive surgery (FPMRS) and the role they play in improving patient education. The authors conducted a keyword search using the search tab in the Apple App Store. The apps selected were ones that specifically pertained to female pelvic medicine. A total of 13 apps were found. The apps were separated into three categories: patient education (five apps), wellness (four apps), and reference (four apps). The majority of the patient education apps consisted of anatomical di...
Source: Current Urology Reports - January 29, 2015 Category: Urology & Nephrology Source Type: research

Positive Surgical Margins in Radical Prostatectomy Patients Do Not Predict Long‐term Oncological Outcomes: Results from SEARCH
ConclusionsPSMs after RP are not an independent risk factor for CRPC, metastasis, or PCSM overall or within any subset. In the absence of other high‐risk features, PSMs alone may not be an indication for adjuvant treatment.This article is protected by copyright. All rights reserved.
Source: BJU International - May 25, 2015 Category: Urology & Nephrology Authors: Prabhakar Mithal, Lauren E. Howard, William J. Aronson, Martha K. Terris, Matthew R. Cooperberg, Christopher J. Kane, Christopher Amling, Stephen J. Freedland Tags: Original Article Source Type: research

Bibliographic references in PubMed and other search engines: Errare humanum est.
Authors: Martínez-Castelao A PMID: 26306943 [PubMed - as supplied by publisher]
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - August 28, 2015 Category: Urology & Nephrology Tags: Nefrologia Source Type: research

Pathologic gleason 8‐10: do all men do poorly? results from the search database
ConclusionIn patients with high grade (Gleason 8‐10) prostate cancer after RP, the presence of either positive SM, ECE, or SVI are all associated with an increased risk of early BCR with 2‐year BCR risk of 50% or higher. On the contrary, men with organ‐confined margin‐negative disease have a very low risk of early BCR despite Gleason 8‐10 disease.This article is protected by copyright. All rights reserved.
Source: BJU International - September 9, 2015 Category: Urology & Nephrology Authors: Sean Fischer, Daniel Lin, Ross M. Simon, Lauren Howard, William J. Aronson, Martha K. Terris, Christopher J. Kane, Christopher L. Amling, Matt R. Cooperberg, Stephen J. Freedland, Adriana C. Vidal Tags: Original Article Source Type: research