Metformin does not affect risk of biochemical recurrence following radical prostatectomy: results from the SEARCH database

Metformin does not affect risk of biochemical recurrence following radical prostatectomy: results from the SEARCH database Prostate Cancer and Prostatic Diseases advance online publication, October 8 2013. doi:10.1038/pcan.2013.48 Authors: E H Allott, M R Abern, L Gerber, C J Keto, W J Aronson, M K Terris, C J Kane, C L Amling, M R Cooperberg, P G Moorman &S J Freedland
Source: Prostate Cancer and Prostatic Diseases - Category: Urology & Nephrology Authors: Tags: metformin diabetes biochemical recurrence outcomes Source Type: research

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Conclusions: Diabetes increased the risk of all-cause mortality among breast, prostate, and colorectal cancer survivors, not for pre- or post-diagnosis diabetes. Greater attention on diabetes management is warranted in cancer survivors with diabetes.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Source: Fertility News - Doctors Lounge - Category: Reproduction Medicine Tags: Cardiology, Oncology, Pharmacy, Reproductive Medicine, Diabetes, News, Source Type: news
(Physicians Committee for Responsible Medicine) Nutrition researcher and New York Times bestselling author Neal Barnard, MD, demonstrates how foods affect our hormones--and our health--in his new book, Your Body in Balance. Dr. Barnard shares the science behind how common conditions--like infertility, weight gain, menopausal symptoms, breast and prostate cancers, thyroid problems, and acne--are fueled by hormones that are hidden in or influenced by the foods we eat.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
In women, testosterone may increase the risk for type 2 diabetes, while in men it lowers that risk. But high levels of testosterone increase the risk for breast and endometrial cancer in women and prostate cancer in men, the researchers reported.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Recently there has been much discussion and many questions about vegan diets. Are vegan diets — which exclude meat, poultry, seafood, eggs, and dairy — healthful? Do they provide complete nutrition? Should I try one? Will it help me lose weight? Many people around the world eat plant-based diets for a variety of reasons, some because meat is not readily available or affordable, others because of religious convictions or concerns about animal welfare. Health has become another reason people are moving to plant-based diets. And research supports the idea that plant-based diets, including vegan diets, provide heal...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Healthy Eating Source Type: blogs
RARITAN, N.J., February 3, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today multiple data presentations from a robust solid tumor portfolio that will be featured at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place February 13-15 in San Francisco. Company-sponsored data presentations will include clinical results for ERLEADA® (apalutamide) and niraparib in prostate cancer; and BALVERSA™ (erdafitinib) in bladder cancer. “We are committed to improving outcomes in patients with prostate and bladder cancer where high unmet ...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Authors: Tieri M, Ghelfi F, Vitale M, Vetrani C, Marventano S, Lafranconi A, Godos J, Titta L, Gambera A, Alonzo E, Sciacca S, Riccardi G, Buscemi S, Del Rio D, Ray S, Galvano F, Beck E, Grosso G Abstract Whole grains have been associated with a number of health benefits. We systematically reviewed existing meta-analyses of observational studies and evaluated the level of evidence for their putative effects based on pre-selected criteria. Of the 23 included studies, we found convincing evidence of an inverse association between whole grain consumption and risk of type-2 diabetes and colorectal cancer; possible evid...
Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
Telephone intervention linked to rise in men ’s vegetable consumption but not to drop in risk of progression Related items fromOnMedica Less regular PSA screening puts men at risk NICE guidance delays hinder good diabetes care Population weight control best for cutting diabetes prevalence Starting statins not beneficial in many older adults NHS must hold CCGs accountable for poor diabetes care
Source: OnMedica Latest News - Category: UK Health Source Type: news
ConclusionMetformin and statins were not associated with BFFS or DFFS improvement in our analysis. However, the small number of patients treated with these drugs limits the reliability of the results and prospective studies are needed.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Authors: Wilson KM, Mucci LA Abstract A variety of diet and lifestyle factors have been studied with respect to prostate cancer risk in large, prospective cohort studies. In spite of this work, and in contrast to other common cancers, few modifiable risk factors have been firmly established as playing a role in prostate cancer. There are several possible explanations for the lack of well-established risk factors. First, prostate cancer has among the highest heritability of all common cancers; second, early life exposures may play an important role in risk, rather than mid- and later-life exposures assessed in most ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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