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Cancer Burden and Control in the Western Pacific Region: Challenges and Opportunities
Conclusions Strengthening cancer registration, tobacco control, and promotion of a healthy diet, as well as HBV and HPV vaccination, is the priority areas to reduce cancer burden. Health-system strengthening with a defined package of services at different levels, referral care, trained human resources, and appropriate technology is necessary to improve cancer management. Pain relief and palliative care are priorities as well. A well-planned national cancer control program with a strong component of surveillance and monitoring can help to reduce the cancer burden in LMICs and Pacific Island countries.
Source: Annals of Global Health - December 13, 2014 Category: Global & Universal Source Type: research
The Most Exciting Health Stories Of 2014
While 2014 will forever be known as the year of the world's biggest Ebola outbreak -- and the first cases of Ebola contracted in the United States -- the virus is just one of several impactful changes in our medical and personal health landscape. From cancer research breakthroughs to innovative food policies to strides in the search for an HIV vaccine, we're quite a bit further in our understanding of medicine than we were last year.
Thanks to research in 2014...
Your Fitness Tracker Data Could Lead To The Next Big Medical Discovery
Your FitBit, Jawbone and other personal tracking devices and apps are logging every s...
Source: Science - The Huffington Post - December 16, 2014 Category: Science Source Type: news
A phase I dose escalation trial of MAGE-A3- and HPV16-specific peptide immunomodulatory vaccines in patients with recurrent/metastatic (RM) squamous cell carcinoma of the head and neck (SCCHN)
Conclusions
GL-0810 and GL-0817 were well tolerated in patients with RM–SCCHN with T cell and antibody responses observed in the majority of patients who received all four vaccinations.
Source: Cancer Immunology, Immunotherapy - December 23, 2014 Category: Cancer & Oncology Source Type: research
January Cervical Cancer Month: Progress Is Promising
January is Cervical Cancer Month. So it is time to look at what has been accomplished recently in control of this disease.
Getting treatment for advanced cervical cancer is challenging. Patients often have pelvic pain, sometimes with blockage of intestines and the urinary tract. Regrettably many patients have fistulas (holes) develop where they leak urine or stool through the skin, vagina or bladder. These are cruel consequences of failed cancer control. About 13,000 women will develop cervical cancer every year, and tragically 4,000 will die of the illness.
In 2014, the FDA approved a new treatment for advanced cervical...
Source: Healthy Living - The Huffington Post - January 9, 2015 Category: Consumer Health News Source Type: news
A Phase I Clinical Trial of CD1c (BDCA-1)+ Dendritic Cells Pulsed With HLA-A*0201 Peptides for Immunotherapy of Metastatic Hormone Refractory Prostate Cancer
Preclinical studies have suggested that purified populations of CD1c (BDCA-1+) blood-derived dendritic cells (BDC) loaded with tumor-specific peptides may be a feasible option for prostate cancer immunotherapy. We performed an open-label dose-finding Phase I study to evaluate the safe use of CD1c+ BDC in patients with advanced metastatic hormone refractory prostate cancer. HLA-A*0201-positive patients with advanced metastatic prostate cancer were recruited and consented. The vaccine was manufactured by pulsing autologous CD1c+ BDC, prepared by magnetic bead immunoselection from apheresed peripheral blood mononuclear cells,...
Source: Journal of Immunotherapy - February 1, 2015 Category: Allergy & Immunology Tags: Clinical Studies Source Type: research
New HPV vaccine may protect against 90% of cervical cancers
Conclusion
This double-blind randomised trial has shown that the new HPV vaccine provides increased protection from additional strains of HPV that cause cervical, vulval and vaginal cancers.
Strengths of the study include:
Blinding of the pathologists to the vaccine type, and blinding of the participants (they didn't know which vaccine they had been given), which reduces any bias – a double-blind randomised controlled trial is considered the gold standard of how best to assess a treatment or intervention.
The large number of women included in the study, with diverse ethnic backgrounds, makes it likely that the res...
Source: NHS News Feed - February 20, 2015 Category: Consumer Health News Tags: Cancer Medication Source Type: news
Awareness of human papillomavirus and factors associated with intention to obtain HPV vaccination among Korean youth: quasi experimental study
Conclusions:
Increased HPV knowledge could positively influence the intention to obtain the HPV vaccination among youth. Thus, HPV education at elementary school would be helpful to make students aware of HPV and the importance of HPV prevention.
Source: BMC International Health and Human Rights - February 21, 2015 Category: Global & Universal Authors: Hae Kim Source Type: research
Top-Line Questions From Moms About MMR
We all want our children to be safe and healthy. Measles is a serious and highly contagious disease, but, fortunately, we can prevent it with immunizations. The measles, mumps, and rubella (MMR) vaccine is safe and the best way to protect your child against measles and other diseases.
I understand that some parents are concerned about vaccines. The evidence about the vaccine's safety and benefits is strong and consistent. There is a lot of inaccurate information circulating about the measles vaccine, so let's make sure we separate the facts from the myths. If you have any concerns or questions, talk to your child's health...
Source: Healthy Living - The Huffington Post - February 28, 2015 Category: Consumer Health News Source Type: news
Clinical trial offers patient ‘best shot’ at fighting kidney cancer
The pain Anne Holmes felt in her arm was actually kidney cancer that had spread. She joined a phase 3 clinical trial. The trial tests a new approach that strips the invisibility cloak from spreading kidney cancer cells; it will use Holmes' own cells to create a vaccine tailored for her cancer cells.
Source: ScienceDaily Headlines - April 20, 2015 Category: Science Source Type: news
By 2020, The Most Common HPV-Related Cancer Will Affect Men
While currently recommended for both boys and girls, the HPV vaccine was initially marketed -- and is still thought of -- as a way to protect young women and girls from cervical, vaginal and vulvar cancer. Boys, it's been commonly thought, should be vaccinated primarily to benefit herd immunity and any future female partners.
But a new analysis from researchers at the Princess Margaret Cancer Center in Toronto, Canada, points out that boys who get the vaccine receive important protection as well, not only against genital warts, but against HPV strains that cause oropharyngeal (mouth and throat) cancer.
"We believe this s...
Source: Science - The Huffington Post - April 20, 2015 Category: Science Source Type: news
Abstract P2-15-03: A Phase Ib Study of an adjuvant GM-CSF-Secreting Breast Cancer Vaccine
Background: Vaccination with tumor cells engineered to secrete granulocyte-macrophage colony stimulating factor (GM-CSF) generates potent, specific, and long-lasting anti-tumor immunity in multiple tumor models. Here, we present analysis on the safety, feasibility, and biologic activity of an autologous GM-CSF-secreting breast cancer vaccine in the high-risk adjuvant setting.
Methods: Following IRB approval and patient consent, 18 patients with stage II-III breast cancer underwent tumor procurement for vaccine development at the time of breast surgery. Patients were required to have at least 4 cm of primary tumor, or have ...
Source: Cancer Research - April 30, 2015 Category: Cancer & Oncology Authors: Anderson, K. S., Overmoyer, B., Canning, C., Savoie, J., Wallstrom, G., Winer, E. P., Dranoff, G. Tags: Poster Session Abstracts Source Type: research
Stopping Cancer Before It Starts
On May 20, 2015, New York State will host its Cancer Prevention Summit in Manhattan.
This bold initiative is the work of the New York State Commissioner of Health, Dr. Howard Zucker, and his colleagues at the New York State Department of Health. Many health related organizations in New York are participating in the Summit, and the audience will be challenged with action points. I am honored to participate in the Cancer Prevention Summit as a speaker, and will introduce the keynote speaker, Dr. Graham Colditz, an internationally recognized leader in the prevention of cancer and other diseases.
The Summit's focus is the p...
Source: Science - The Huffington Post - May 18, 2015 Category: Science Source Type: news
How was Henrietta Harmed?
The HeLa LegacyI recently had the pleasure of meeting two of Henrietta Lacks’ descendants when I participated in a panel discussion with her granddaughter Kimberly Lacks and her great-granddaughter Veronica Spencer at Metropolitan Community College, Longview’s Spring Convocation on April 16th, 2015. The story of Henrietta Lacks was chronicled in the best-selling book The Immortal Life of Henrietta Lacks by Rebecca Skloot. This African-American woman, who died in 1951, is the source of the famous HeLa cells. These cells, obtained from a biopsy of Henrietta’s cancerous cervix, are unique; they are immortal ...
Source: blog.bioethics.net - June 14, 2015 Category: Medical Ethics Authors: Practical Bioethics Tags: Health Care syndicated Source Type: blogs
Avoiding the Doctor? It’s Time to Man Up and Get a Checked Out
Do you know someone who should have seen a doctor years ago? Maybe it’s your husband, or your father, or your brother, even your son? They complain about the shortness of breath, the nagging cough, or the stomach pain. But they never take action. For some men, so decisive at work or within the family circle, the lack of motivation to get an illness or symptom checked out is surprising. In fact, men are 24% less likely to have visited a doctor in the past year than women. Seeing a doctor is scary and it makes them feel weak and out of control.
Roald Bradstock was one of those men. An Olympic athlete who trained 3 to 4...
Source: Disruptive Women in Health Care - June 15, 2015 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Men's Health Source Type: blogs
Avoiding the Doctor? It’s Time to Man Up and Get Checked Out
Do you know someone who should have seen a doctor years ago? Maybe it’s your husband, or your father, or your brother, even your son? They complain about the shortness of breath, the nagging cough, or the stomach pain. But they never take action. For some men, so decisive at work or within the family circle, the lack of motivation to get an illness or symptom checked out is surprising. In fact, men are 24% less likely to have visited a doctor in the past year than women. Seeing a doctor is scary and it makes them feel weak and out of control.
Roald Bradstock was one of those men. An Olympic athlete who trained 3 to 4...
Source: Disruptive Women in Health Care - June 15, 2015 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Men's Health Source Type: blogs
