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Vaccination: Cancer Vaccines

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Total 479 results found since Jan 2013.

Perspectives on Immunotherapy in Prostate Cancer and Solid Tumors: Where Is the Future?
The goals of any cancer therapy are to improve disease control, palliate pain and improve overall survival. We are fortunate to have in our cancer armamentarium two new immune-directed therapies which not only impact on disease control but also on overall survival. The first, sipuleucel-T, a cellular-based vaccine, was approved for prostate cancer and was shown to be safe with minimal toxicity. The second, ipilimumab, a monoclonal antibody directed to an immunologic checkpoint molecule, showed a survival benefit in patients with advanced melanoma. Benefit appeared to correlate in some cases with the development of autoimmu...
Source: Seminars in Oncology - June 1, 2013 Category: Cancer & Oncology Authors: Alexandra Snyder, Jaron E. Tepper, Susan F. Slovin Tags: Adam P. Dicker, MD, PhD, Leonard G. Gomella, MD, FACS, and Wm. Kevin Kelly, DO, Guest Editors Source Type: research

Tamiflu saga continues - NYT. By Katie Thomas
Breaking the Seal on Drug ResearchPETER DOSHI walked across the campus of Johns Hopkins University in a rumpled polo shirt and stonewashed jeans, a backpack slung over one shoulder. An unremarkable presence on a campus filled with backpack-toters, he is 32, and not sure where he’ll be working come August, when his postdoctoral fellowship ends. And yet, even without a medical degree, he is one of the most influential voices in medical research today.Dr. Doshi’s renown comes not from solving the puzzles of cancer or discovering the next blockbuster drug, but from pushing the world’s biggest pharmaceutical companie...
Source: PharmaGossip - June 30, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs

New approach to managing genital warts.
CONCLUSION: The new treatments of external genital warts can reduce the pain of treatment and the number of office visits. Other treatment methods are still useful in certain situations. PMID: 23851535 [PubMed - in process]
Source: Canadian Family Physician Medecin de Famille Canadien - July 1, 2013 Category: Primary Care Authors: Lopaschuk CC Tags: Can Fam Physician Source Type: research

Vaccines Can Cause Infertility
Conclusion What I have discovered, I am sure that many would agree, is absolutely horrific. It appears that many of the recommended vaccinations are known by the governments and pharmaceutical industries to cause infertility. Many of these vaccines are mandatory. We need to ask ourselves why our governments are deliberately force-vaccinating us with vaccines known to cause infertility. Another question we need to ask is why are so many studies being funded to study the subject area surrounding vaccines and infertility. Many leading professionals believe that these vaccines are being offered as part of a global depopulation...
Source: vactruth.com - July 20, 2013 Category: Health Medicine and Bioethics Commentators Authors: Christina England Tags: Christina England Top Stories infertility Premature Ovarian Failure Sterilization Tetanus Vaccines Vaccine Safety Source Type: blogs

It's an epidemic!
OMG! The incidence of thyroid cancer has tripled in the U.S. in the past 30 years, from 3.6 cases/100,000 to 11.6. Is it radioactive fallout? Pesticides? Vaccination? Fluoridation?Nope. It's CT scans. And you can relax. They aren't causing thyroid cancer, they're finding abnormal cells which in the past, nobody would have detected. But, as Brito, Morris and Montori tell us at the linked article (which I don't think you can read but that's okay, I'll tell you what's in it), they aren't actually cancer after all.There are four different kinds of thyroid "cancer," the most common of which is called papillary carcinoma. Guess ...
Source: Stayin' Alive - August 30, 2013 Category: Health Medicine and Bioethics Commentators Source Type: blogs

Adjuvant breast cancer vaccine improves disease specific survival of breast cancer patients with depressed lymphocyte immunity
Conclusion: This study confirms the importance of maintaining good host lymphocyte immunity after completion of standard therapy and validates the value of cancer immunotherapy in the adjuvant setting.
Source: Surgical Oncology - June 24, 2013 Category: Surgery Authors: Robert L. Elliott, Jonathan F. Head Tags: General Papers Source Type: research

Egypt’s Poor Easy Victims of Quack Medicine
Many pharmacies and herbalists in Egypt prescribe their own 'wasfa' (secret drug or herbal elixir). Credit: Cam McGrath/IPSBy Cam McGrathCAIRO, Aug 10 2014 (IPS) Magda Ibrahim first learnt that she had endometrial cancer when she went to a clinic to diagnose recurring bladder pain and an abnormal menstrual discharge. Unable to afford the recommended hospital treatment, the uninsured 53-year-old widow turned to what she hoped would be a quicker and cheaper therapy. A local Muslim sheikh claimed religious incantations, and a suitable donation to his pocket, could cure the cancer. But when her symptoms persisted, Ibrahim cons...
Source: IPS Inter Press Service - Health - August 10, 2014 Category: Global & Universal Authors: Cam McGrath Tags: Civil Society Education Featured Headlines Health Human Rights Middle East & North Africa Poverty & MDGs Projects Women's Health AIDS avian flu blood dialysis clinics Corruption Doctors Egypt Health care Hepatitis C h Source Type: news

Safety and immunogenicity of a quadrivalent human papillomavirus vaccine in HIV-infected and HIV-negative adolescents and young adults.
Abstract Human papillomavirus (HPV) infection is highly prevalent and can lead to cancer; the development of safe and efficacious vaccines for HPV is a major public health concern. The two licensed HPV vaccines contain recombinant virus-like particles of HPV 16 and 18; one of such vaccines also protects against HPV types 6 and 11 which cause genital warts. We determined safety and immunogenicity of quadrivalent HPV vaccine in HIV-infected and HIV-negative adolescents and young adults, aged 13-27 years. The seroconversion rate, assessed by antibody titers, 1 month after the administration of the third vaccine dose ...
Source: Vaccine - August 19, 2014 Category: Allergy & Immunology Authors: Giacomet V, Penagini F, Trabattoni D, Viganò A, Rainone V, Bernazzani G, Bonardi CM, Clerici M, Bedogni G, Zuccotti GV Tags: Vaccine Source Type: research

Views on Human Papillomavirus Vaccination: A Mixed-Methods Study of Urban Youth
Abstract While the human papillomavirus (HPV) vaccine has potential to protect against the majority of HPV-associated cancers, vaccination rates in the United States remain low. Racial/ethnic and economic disparities exist for HPV vaccination completion rates. We conducted a mixed-methods study using the theory of planned behavior framework to explore attitudes and beliefs about HPV vaccination among urban, economically disadvantaged adolescents. Fifty adolescents aged 14–18 years were recruited from community-based organizations to complete a written survey and participate in a focus group. The mean age was 1...
Source: Journal of Community Health - September 26, 2014 Category: Global & Universal Source Type: research

Abstract CT331: Phase I/II trial of a novel antibody DNA immunotherapy, targeting CD64, in the treatment of Melanoma
Conclusion: We demonstrate that SCIB1 is safe in melanoma patients. 19/20 patients showed immune responses to repeat dosing at 2 or 4 mg. Detection of an objective clinical response and overall survival times are encouraging. 1. Pudney et al (2010). Eur J Immunol 40: 899. 2. Brentville et al (2012). Plos one 7:e4111 Citation Format: Lindy G. Durrant, Christian H. Ottensmeier, Paul Lorigan, Clive Mulatero, Ruth Plummer, Michelle Cunell, Rachael Metheringham, Victoria Brentville, Lee Machado, Poulam Patel. Phase I/II trial of a novel antibody DNA immunotherapy, targeting CD64, in the treatment of Melanoma. [abstract]. In: Pr...
Source: Cancer Research - September 30, 2014 Category: Cancer & Oncology Authors: Durrant, L. G., Ottensmeier, C. H., Lorigan, P., Mulatero, C., Plummer, R., Cunell, M., Metheringham, R., Brentville, V., Machado, L., Patel, P. Tags: Clinical Trials Source Type: research

Volume: 20 Issue: 5
This study explored whether a newly developed initiative could help alleviate the strain on the health care system associated with COPD and its sequelae. Using a virtual game system to innovate pulmonary rehabilitation: Safety, adherence and enjoyment in severe chronic obstructive pulmonary diseasePhysical activity represents an important component of rehabilitation programs in patients with chronic obstructive pulmonary disease. Maintaining high levels of physical activity following completion of rehabilitation programs, however, has proven challenging for many patients. This pilot study assessed the feasibility of incorp...
Source: Canadian Respiratory Journal - November 20, 2014 Category: Respiratory Medicine Source Type: research

Navigating the Treatment Landscape
for Advanced-stage Kidney Cancer Mayer N. Fishman, MD, PhD For the patient with advanced-stage kidney cancer, deciding on a course of treatment presents diverse choices. The physician must weigh how quickly the cancer is spreading, the pattern of that spread, and relative risks from other medical conditions against the patient’s individual treatment goals and medical needs. In many cases of patients with advanced disease, there are therapies that can realistically be used to meet the goals of longer survival, longer time to disease progression, and tumor shrinkage. While choosing a kidney cancer treatment can ...
Source: Kidney Cancer Association - December 3, 2014 Category: Cancer & Oncology Source Type: news

North Texas Fracking Zone Sees Growing Health Worries
This story was published by The Center for Public Integrity, a nonprofit, nonpartisan investigative news organization in Washington, D.C. DALLAS—Propped up on a hospital bed, Taylor Ishee listened as his mother shared a conviction that choked her up. His rare cancer had a cause, she believes, and it wasn’t genetics. Others in Texas have drawn the same conclusions about their confounding illnesses. Jana DeGrand, who suffered a heart attack and needed both her gallbladder and her appendix removed. Rebecca Williams, fighting off unexplained rashes, sharp headaches and repeated bouts of pneumonia. Maile Bush, who needed ...
Source: Science - The Huffington Post - December 11, 2014 Category: Science Source Type: news

New HPV Vaccine Is Even More Effective Against Cancer
WASHINGTON (AP) — The drugmaker Merck & Co. Inc. has received approval for an updated version of its Gardasil vaccine that protects against an additional five strains of the virus that causes most cases of cervical cancer. The Food and Drug Administration approved the company's Gardasil 9, which protects against nine strains of the virus called HPV, or human papillomavirus. That's up from four strains covered by the original Gardasil vaccine approved in 2006. The FDA said Wednesday the updated Gardasil has the potential to prevent roughly 90 percent of cervical, vulvar, vaginal and anal cancers. Original Gardasil protec...
Source: Science - The Huffington Post - December 11, 2014 Category: Science Source Type: news