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Procedure: Kidney Transplant
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Total 40381 results found since Jan 2013.
Impact of pre-transplant dialysis modality on kidney transplant outcomes: a systematic review and meta-analysis
CONCLUSIONS: Within the limitations of the review, it can be concluded that ESRD patients undergoing pre-transplant PD were found to have better patient survival and lower incidence of delayed graft function.PMID:35442484 | DOI:10.26355/eurrev_202204_28459
Source: Pharmacological Reviews - April 20, 2022 Category: Drugs & Pharmacology Authors: Y-F Hou X-X Wang H-J Yang S Zhong Source Type: research
Upper limb exercise for arteriovenous fistula maturation in people requiring permanent haemodialysis access
CONCLUSIONS: Our findings suggest that the current research evidence examining upper limb exercise programs is of low quality, attributable to variability in the type of interventions used and the overall low number of studies and participants.PMID:36184076 | DOI:10.1002/14651858.CD013327.pub2
Source: Cochrane Database of Systematic Reviews - October 2, 2022 Category: General Medicine Authors: Sothida Nantakool Termpong Reanpang Mujalin Prasannarong Sasinat Pongtam Kittipan Rerkasem Source Type: research
Systematic review and meta-analysis of calcineurin inhibitors on long-term prognosis of renal transplant patients
CONCLUSION: The meta-analysis showed that, compared with cyclosporine, tacrolimus increases the risk of a new-onset diabetes. However, tacrolimus had higher graft survival rate and better creatinine clearance than cyclosporine.PMID:36372141 | DOI:10.1016/j.trim.2022.101741
Source: Transplant Immunology - November 13, 2022 Category: Transplant Surgery Authors: Kang Yang Meiling Zhang Beining Zhang Yingshi Zhang Qingchun Zhao Source Type: research
Timing of kidney replacement therapy initiation for acute kidney injury
CONCLUSIONS: Based on mainly low to moderate certainty of the evidence, early KRT has no beneficial effect on death and may increase the recovery of kidney function. Earlier KRT probably reduces the length of ICU and hospital stay but increases the risk of adverse events. Further adequate-powered RCTs using robust and validated tools that complement clinical judgement are needed to define the optimal time of KRT in critical patients with AKI in order to improve their outcomes. The surgical AKI population should be considered in future research.PMID:36416787 | DOI:10.1002/14651858.CD010612.pub3
Source: Cochrane Database of Systematic Reviews - November 23, 2022 Category: General Medicine Authors: Alicia Isabel Fayad Daniel G Buamscha Agust ín Ciapponi Source Type: research
Interventions for dialysis patients with hepatitis C virus (HCV) infection
CONCLUSIONS: In dialysis patients with HCV infection grazoprevir plus elbasvir probably improves ETR. There is no difference in ETR or SVR for combinations of telaprevir, ribavirin and PEG interferon given for different durations and doses. Though no longer in use, PEG interferon was more effective than standard interferon for ETR but not SVR. Increasing doses of PEG interferon did not improve responses. The addition of ribavirin to PEG interferon may result in fewer relapses, higher SVR, and higher numbers with adverse events.PMID:37096802 | DOI:10.1002/14651858.CD007003.pub3
Source: Cochrane Database of Systematic Reviews - April 25, 2023 Category: General Medicine Authors: Attur Ravindra Prabhu Indu Ramachandra Rao Shankar Prasad Nagaraju Eti Rajwar Bhumika T Venkatesh Sreekumaran Nair N Ganesh Pai Nageswara P Reddy Deepak Suvarna Source Type: research
Fight Aging! Newsletter, May 22nd 2023
Conclusions to be Drawn
A High Fat Diet Accelerates Atherosclerosis Less Directly than One Might Suspect
How to Construct Measures of Biological Age
A Long-Term Comparison of Metformin in Diabetics with Non-Diabetic Controls
In Search of Distinctive Features of the Gut Microbiome in Long-Lived Individuals
Greater Fitness in Humans Implies a Younger Epigenome and Transcriptome
Intestinal Barrier Dysfunction as a Feature of Aging in Many Species
NAFLD as an Age-Related Condition
Towards Sensory Hair Cell Regeneration in the Inner Ear
Raised Levels of PLG...
Source: Fight Aging! - May 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Intensive glucose control versus conventional glucose control for type 1 diabetes mellitus.
CONCLUSIONS: Tight blood sugar control reduces the risk of developing microvascular diabetes complications. The evidence of benefit is mainly from studies in younger patients at early stages of the disease. Benefits need to be weighed against risks including severe hypoglycaemia, and patient training is an important aspect in practice. The effects of tight blood sugar control seem to become weaker once complications have been manifested. However, further research is needed on this issue. Furthermore, there is a lack of evidence from RCTs on the effects of tight blood sugar control in older patient populations or patients w...
Source: Cochrane Database of Systematic Reviews - February 14, 2014 Category: Journals (General) Authors: Fullerton B, Jeitler K, Seitz M, Horvath K, Berghold A, Siebenhofer A Tags: Cochrane Database Syst Rev Source Type: research
Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients.
CONCLUSIONS: Although there were some favourable aspects associated with Cordyceps, longer-term studies are needed to clarify any benefit-harm trade-off. Future studies should investigate the use of Cordyceps in combination with other immunosuppressive agents such as tacrolimus, mycophenolate mofetil or induction therapy. Such studies also need to be appropriately sized and powered.
PMID: 26457607 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - October 12, 2015 Category: Journals (General) Authors: Hong T, Zhang M, Fan J Tags: Cochrane Database Syst Rev Source Type: research
Kidney and liver organ transplantation in persons with human immunodeficiency virus: An Evidence-Based Analysis.
The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+)
CLINICAL NEED: CONDITION AND TARGET POPULATION Patients with end stage organ failure who have been unresponsive to other forms of treatment eventually require solid organ transplantation. Similar to persons who are HIV negative (HIV-), persons living with HIV infection (HIV+) are at risk for ESOF from viral (e.g. hepatitis B and C) and non-viral aetiologies (e.g. coronary artery disease, diabetes, hepatocellular carcinoma). Additionally, H...
Source: Ontario Health Technology Assessment Series - December 20, 2015 Category: Journals (General) Tags: Ont Health Technol Assess Ser Source Type: research
Fight Aging! Newsletter, August 15th 2016
In conclusion, our results demonstrate that circulating GDF11 levels are reduced in our mouse model of premature aging, which shares most of the symptoms that occur in normal aging. However, GDF11 protein administration is not sufficient to extend longevity in these progeroid mice. Although accelerated-aging mouse models can serve as powerful tools to test and develop anti-aging therapies common to both physiological and pathological aging, the existence of certain differences between the two processes implies that further investigation is still required to determine whether long-term GDF11 administration has a pro-surviva...
Source: Fight Aging! - August 14, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, July 17th 2017
This study aimed to estimate associations between combined measurements of BMI and waist-to-hip ratio (WHR) with mortality and incident coronary artery disease (CAD). This study followed 130,473 UK Biobank participants aged 60-69 years (baseline 2006-2010) for 8.3 years (n = 2974 deaths). Current smokers and individuals with recent or disease-associated (e.g., from dementia, heart failure, or cancer) weight loss were excluded, yielding a "healthier agers" group.
Ignoring WHR, the risk of mortality for overweight subjects was similar to that for normal-weight subjects. However, among normal-weight subjects, mortalit...
Source: Fight Aging! - July 16, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Probiotics for preventing urinary tract infection in people with neuropathic bladder.
CONCLUSIONS: In this review, there were no studies identified addressing oral probiotics in preventing UTI in people with neuropathic bladder. It is uncertain if the risk of symptomatic UTI is reduced in people with neuropathic bladders via intravesical instillation of non-pathogenic E. coli as data were derived from small studies with high risk of bias.Although very minimal levels of harm was reported with this procedure, due to variable success rates, the need for strict adherence to instillation protocols together with high attrition rates in these studies, it is doubtful bladder instillation will be a widely accepted i...
Source: Cochrane Database of Systematic Reviews - September 8, 2017 Category: General Medicine Authors: Toh SL, Boswell-Ruys CL, Lee BSB, Simpson JM, Clezy KR Tags: Cochrane Database Syst Rev Source Type: research
