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Vaccination: Malaria Vaccine
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Total 1513 results found since Jan 2013.
Travelling with children and adolescents with rheumatic diseases
Z Rheumatol. 2021 Apr 27:1-9. doi: 10.1007/s00393-021-01002-6. Online ahead of print.ABSTRACTDue to the underlying disease and immunosuppressive treatment, pediatric patients with rheumatic diseases are at increased risk for (long distance) travel-related health problems. A pretravel comprehensive consultation is therefore strongly recommended. Whether a child with rheumatic disease is sufficiently fit for travel essentially depends on the disease activity, the age of the child and the intended travel destination. Depending on the level of immunosuppression, the risks for this patient group include (travel-related) infecti...
Source: Zeitschrift fur Rheumatologie - April 27, 2021 Category: Rheumatology Authors: M Freudenhammer M Hufnagel Source Type: research
Antigenic sites in SARS-CoV-2 spike RBD show molecular similarity with pathogenic antigenic determinants and harbors peptides for vaccine development
Immunobiology. 2021 Jul 13;226(5):152091. doi: 10.1016/j.imbio.2021.152091. Online ahead of print.ABSTRACTThe spike protein of coronavirus is key target for drug development and other pharmacological interventions. In current study, we performed an integrative approach to predict antigenic sites in SARS-CoV-2 spike receptor binding domain and found nine potential antigenic sites. The predicted antigenic sites were then assessed for possible molecular similarity with other known antigens in different organisms. Out of nine sites, seven sites showed molecular similarity with 54 antigenic determinants found in twelve pathogen...
Source: Immunobiology - July 25, 2021 Category: Allergy & Immunology Authors: Tikam Chand Dakal Source Type: research
Efforts Made to Eliminate Drug-Resistant Malaria and Its Challenges
Biomed Res Int. 2021 Aug 30;2021:5539544. doi: 10.1155/2021/5539544. eCollection 2021.ABSTRACTSince 2000, a good deal of progress has been made in malaria control. However, there is still an unacceptably high burden of the disease and numerous challenges limiting advancement towards its elimination and ultimate eradication. Among the challenges is the antimalarial drug resistance, which has been documented for almost all antimalarial drugs in current use. As a result, the malaria research community is working on the modification of existing treatments as well as the discovery and development of new drugs to counter the res...
Source: Biomed Res - September 9, 2021 Category: Research Authors: Wote Amelo Eyasu Makonnen Source Type: research
RNA-based therapeutics to treat human fungal infections
Trends Microbiol. 2021 Oct 8:S0966-842X(21)00218-3. doi: 10.1016/j.tim.2021.09.007. Online ahead of print.ABSTRACTIn recent decades, RNA-based therapeutics have transitioned from a near impossibility to a compelling treatment alternative for genetic disorders and infectious diseases. The mRNA vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are truly groundbreaking, and new adaptations are already being proposed to fight other microbes. Unfortunately, the potential of RNA-based therapeutics to treat human fungal infections has remained mostly absent from the conversation, despite the fact that ...
Source: Trends in Microbiology - October 12, 2021 Category: Microbiology Authors: Alexander Bruch Abdulrahman A Kelani Matthew G Blango Source Type: research
World Health Organization recommends first malaria vaccine
Can J Public Health. 2021 Nov 30:1-3. doi: 10.17269/s41997-021-00593-6. Online ahead of print.NO ABSTRACTPMID:34846704 | PMC:PMC8631257 | DOI:10.17269/s41997-021-00593-6
Source: Canadian Journal of Public Health - November 30, 2021 Category: International Medicine & Public Health Authors: Helen Trottier Susan J Elliott Source Type: research
