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Nutrition: Herbs
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Total 24253 results found since Jan 2013.
Molecular docking analysis of GC-MS analyzed bioactive compounds from the rhizome of Hedychium rubrum with four protein targets
Bioinformation. 2022 Oct 31;18(10):943-950. doi: 10.6026/97320630018943. eCollection 2022.ABSTRACTHedychium rubrum, a traditional medicinal plant of Manipur belonging to the family Zingeberaceae was screened for its biological activity. The methanolic extract of its rhizome was prepared by Soxhlet extraction method and was further subjected to GC-MS to know its bioactive compounds. The in vitro antimicrobial activity assay was tested against five bacteria causing UTI. Klebseilla pneumoniae showed most sensitive followed by Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Enterococcus faecalis in the orde...
Source: Bioinformation - September 1, 2023 Category: Bioinformatics Authors: Ksh Sangeeta Devi M Damayanti Devi N Chetan Das D Velmurugan N Rajen Singh Source Type: research
Herbal melanin modulates PGE2 and IL-6 gastroprotective markers through COX-2 and TLR4 signaling in the gastric cancer cell line AGS
In conclusion, our results showed that HM enhances TLR4/COX-2-mediated secretion of gastroprotective markers PGE2 and IL-6, and upregulates mucin 4 gene expression in the human gastric epithelial cell line AGS, which may contribute to the promising beneficial gastroprotective effect of HM for human gastric prevention and treatment.PMID:37658354 | DOI:10.1186/s12906-023-04124-3
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Adila El-Obeid Yahya Maashi Rehab AlRoshody Ghada Alatar Modhi Aljudayi Hamad Al-Eidi Nouf AlGaith Altaf Husain Khan Adil Hassib Sabine Matou-Nasri Source Type: research
Molecular docking analysis of GC-MS analyzed bioactive compounds from the rhizome of Hedychium rubrum with four protein targets
Bioinformation. 2022 Oct 31;18(10):943-950. doi: 10.6026/97320630018943. eCollection 2022.ABSTRACTHedychium rubrum, a traditional medicinal plant of Manipur belonging to the family Zingeberaceae was screened for its biological activity. The methanolic extract of its rhizome was prepared by Soxhlet extraction method and was further subjected to GC-MS to know its bioactive compounds. The in vitro antimicrobial activity assay was tested against five bacteria causing UTI. Klebseilla pneumoniae showed most sensitive followed by Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Enterococcus faecalis in the orde...
Source: Bioinformation - September 1, 2023 Category: Bioinformatics Authors: Ksh Sangeeta Devi M Damayanti Devi N Chetan Das D Velmurugan N Rajen Singh Source Type: research
Biomacromolecule-based nanocarrier strategies to deliver plant-derived bioactive components for cancer treatment: A recent review
Int J Biol Macromol. 2023 Aug 30:126623. doi: 10.1016/j.ijbiomac.2023.126623. Online ahead of print.ABSTRACTThe quest for safe chemotherapy has attracted researchers to explore anticancer potential of herbal medicines. Owing to upsurging evidence of herbal drug's beneficial effects, hopes are restored for augmenting survival rates in cancer patients. However, phytoconstituents confronted severe limitations in terms of poor absorption, low-stability, and low bioavailability. Along with toxicity issues associated with phytoconstituents, quality control and limited regulatory guidance also hinder the prevalence of herbal medi...
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Bapi Gorain Varnita Karmakar Biswatrish Sarkar Monika Dwivedi Janelle Tsui Lyn Leong Jing Hen Toh Even Seah Kang Yi Ling Kah Yee Chen Hira Choudhury Manisha Pandey Source Type: research
Preparation of medicinally active extracts and phytochemical characterisation of phytoconstituents from medicinal plants
This study described the Soxhlet and the maceration methods that are used to process extracts from the inert materials of medicinal plants using appropriate biocompatible solvents, the phytochemical screening assays, and TLC, UV spectrometry, FT-IR, and GC-MS techniques used in phytochemical studies. These techniques are crucial in studies that are meant to explore the active components of medicinal plants and their relative pharmacological effects. This information can be used as a guide when formulating effective yet less toxic plant-derived drugs and provide opportunities to upgrade while reducing further complexity in ...
Source: Natural Product Research - September 1, 2023 Category: Biochemistry Authors: Festus S Shafodino Julien M Lusilao Lamech M Mwapagha Source Type: research
Molecular docking analysis of GC-MS analyzed bioactive compounds from the rhizome of Hedychium rubrum with four protein targets
Bioinformation. 2022 Oct 31;18(10):943-950. doi: 10.6026/97320630018943. eCollection 2022.ABSTRACTHedychium rubrum, a traditional medicinal plant of Manipur belonging to the family Zingeberaceae was screened for its biological activity. The methanolic extract of its rhizome was prepared by Soxhlet extraction method and was further subjected to GC-MS to know its bioactive compounds. The in vitro antimicrobial activity assay was tested against five bacteria causing UTI. Klebseilla pneumoniae showed most sensitive followed by Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Enterococcus faecalis in the orde...
Source: Bioinformation - September 1, 2023 Category: Bioinformatics Authors: Ksh Sangeeta Devi M Damayanti Devi N Chetan Das D Velmurugan N Rajen Singh Source Type: research
Biomacromolecule-based nanocarrier strategies to deliver plant-derived bioactive components for cancer treatment: A recent review
Int J Biol Macromol. 2023 Aug 30:126623. doi: 10.1016/j.ijbiomac.2023.126623. Online ahead of print.ABSTRACTThe quest for safe chemotherapy has attracted researchers to explore anticancer potential of herbal medicines. Owing to upsurging evidence of herbal drug's beneficial effects, hopes are restored for augmenting survival rates in cancer patients. However, phytoconstituents confronted severe limitations in terms of poor absorption, low-stability, and low bioavailability. Along with toxicity issues associated with phytoconstituents, quality control and limited regulatory guidance also hinder the prevalence of herbal medi...
Source: International Journal of Biological Macromolecules - September 1, 2023 Category: Biochemistry Authors: Bapi Gorain Varnita Karmakar Biswatrish Sarkar Monika Dwivedi Janelle Tsui Lyn Leong Jing Hen Toh Even Seah Kang Yi Ling Kah Yee Chen Hira Choudhury Manisha Pandey Source Type: research
The apoptotic effect of the Lycopodium clavatum extracts on MCF-7 human breast cancer cells
In this study, we investigated the cytotoxic and apoptotic effects of LC Water Extract (LC-WE) and LC Ethanol Extract (LC-EE) plant extracts on MCF-7 human breast cancer cells. Our results showed that LC treatment led to a dose and time-dependent cytotoxic effect on MCF-7 cells, indicating its potential as an anticancer agent against human breast cancer. Additionally, we observed that LC treatment activated apoptosis-related proteins, including BAX, Caspase-3, and Caspase-9. These results suggest that LC may induce apoptosis as a mechanism underlying its cytotoxic effect on MCF-7 human breast cancer cells. Previous studies...
Source: Medical Oncology - September 1, 2023 Category: Cancer & Oncology Source Type: research
Prevalence, knowledge, and attitudes toward herbal medicines among pregnant women attending antenatal clinic in Prince Mansour Military Hospital in Taif
CONCLUSION: Herbal medicines use during pregnancy is a common practice among women in Taif city, Saudi Arabia. Less frequent ANC visits was associated with high probability of herbal medicine use during pregnancy. Majority of pregnant women agreed that herbals are beneficial if recommended by doctor.PMID:37649749 | PMC:PMC10465024 | DOI:10.4103/jfmpc.jfmpc_295_23
Source: Primary Care - August 31, 2023 Category: Primary Care Authors: Dhelal M Alkhaldi Sawsan S Alkhammash Source Type: research
A Novel Paradigm Defines Functional Molecule Clusters for an Anti-Alzheimer's Disease Recipe from Traditional Chinese Medicine
In this study, a similarity analysis based on molecular fingerprints was adopted to explore the representative molecules of the Tiaoxin recipe, a Chinese patent formula approved by the National Medical Products Administration (NMPA) for the treatment of mild-to-moderate Alzheimer's disease (AD), and 38 out of 1047 chemicals were finally screened out. Next, we tried to define a new concept of a "functional molecule cluster" for chemicals with similar pharmacological effects to elucidate how the chemical mixture from TCMs produce their therapeutic effects. Four anti-AD functional molecule clusters from the Tiaoxin recipe wer...
Source: The American Journal of Chinese Medicine - August 31, 2023 Category: Complementary Medicine Authors: Peiyi Ji Jianrong Xu Miaomiao Li Chenghuan Song Yongfang Zhang Rui Zhang Hongzhuan Chen Hao Wang Lanxue Zhao Source Type: research
