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Fight Aging! Newsletter, December 6th 2021
In this study, they found these drugs can kill senescent cells from cultures of human fat tissue. The tissue was donated by individuals with obesity who were known to have metabolic troubles. Without treatment, the human fat tissues induced metabolic problems in immune-deficient mice. After treatment with dasatinib and quercetin, the harmful effects of the fat tissue were almost eliminated. Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2...
Source: Fight Aging! - December 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Characterization and diversity of native < em > Azotobacter < /em > spp. isolated from semi-arid agroecosystems of Eastern Kenya
This study reports for the first time a wide diversity of Azotobacter species from a semi-arid agroecosystem in Kenya with potential for utilization as low-cost, free-living nitrogen-fixing bioinoculant.PMID:35317624 | PMC:PMC8941396 | DOI:10.1098/rsbl.2021.0612
Source: Biology Letters - March 23, 2022 Category: Biology Authors: Priscillah Wanjira Wakarera Patroba Ojola Ezekiel Mugendi Njeru Source Type: research

Hybrid organic-inorganic membranes based on sulfonated poly (ether ether ketone) matrix and iron-encapsulated carbon nanotubes and their application in CO < sub > 2 < /sub > separation
RSC Adv. 2022 May 4;12(21):13367-13380. doi: 10.1039/d2ra01585d. eCollection 2022 Apr 28.ABSTRACTThe need to reduce greenhouse gas emissions dictates the search for new methods and materials. Here, a novel type of inorganic-organic hybrid materials Fe@MWCNT-OH/SPEEK (with a new type of CNT characterized by increased iron content, 5.80 wt%) for CO2 separation is presented. The introduction of nanofillers into a polymer matrix has significantly improved hybrid membrane gas transport (D, P, S, and α CO2/N2 ), and magnetic, thermal, and mechanical parameters. It was found that magnetic casting has improved the alignment and d...
Source: Adv Data - May 6, 2022 Category: Epidemiology Authors: Aleksandra Rybak Aurelia Rybak S ławomir Boncel Anna Kolanowska Waldemar Kaszuwara Spas D Kolev Source Type: research

Volatile Organic Compounds Analysis as a Potential Novel Screening Tool for Breast Cancer: A Systematic Review
DISCUSSION: Discrepant VOC results among BC studies have been obtained, highly due to methodological discrepancies. Therefore, methodological issues leading to disparities have been reviewed and recommendations have been made on the standardisation of VOC collection and analysis methods for BC screening, thereby improving future VOC clinical validation studies.PMID:35645556 | PMC:PMC9134002 | DOI:10.1177/11772719221100709
Source: Cancer Control - June 1, 2022 Category: Cancer & Oncology Authors: Michelle Leemans Pierre Bau ër Vincent Cuzuel Etienne Audureau Isabelle Fromantin Source Type: research

Thyroid hormone transporters in a human placental cell model
Conclusions Using pharmacological inhibitors, we show that MCT10 and LATs play a major role in T3 uptake in BeWo cells. T4 uptake appears independent of known TH transporters, suggesting the presence of, currently unknown, alternative transporter(s).PMID:35699060 | DOI:10.1089/thy.2021.0503
Source: Thyroid : official journal of the American Thyroid Association - June 14, 2022 Category: Endocrinology Authors: Zhongli Chen A S Elise van der Sman Stefan Groeneweg Linda J de Rooij W Edward Visser Robin P Peeters Marcel E Meima Source Type: research