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Therapy: Chemotherapy
Nutrition: Diets
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Total 657 results found since Jan 2013.
Integration of palliative care in the management of oral squamous cell carcinoma
Bioinformation. 2023 Jan 31;19(1):1-4. doi: 10.6026/97320630019001. eCollection 2023.ABSTRACTOral Squamous cell Cancers (OSCC) is strongly associated with tobacco consumption. We here in present a case study of a OSCC patient who refused standard oncological care (SOC), to highlight the importance of integrating palliative care (PC) for improved patient outcomes. A 61 years male patient, with history of chewing tobacco for more than 20 years and diagnosed to have OSCC for 1.5 years presented with severe anaemia and a cauliflower-like growth (12 x 10 cm) in the left oral cavity and cheek with greenish-yellow discharge. Pus ...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Republica Sridhar Huwait Etimad Peter Natesan Pushparaj Gauthaman Kalamegam Source Type: research
Intratumoral Bacteria as Mediators of Cancer Immunotherapy Response
Cancer Res. 2023 Sep 15;83(18):2985-2986. doi: 10.1158/0008-5472.CAN-23-1857.ABSTRACTMultiple lines of evidence spanning from animal models to human clinical trials indicate that the microbiome influences cancer immunotherapy response. Whereas initial studies focused exclusively on the gastrointestinal (gut) microbiota-tumor axis, more recent studies have examined the possibility that bacteria located within tumor cells or within the tumor microenvironment mediate cancer treatment response. Strikingly, this phenomenon has been demonstrated in cancers that arise in anatomic locations that are traditionally thought to be dev...
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Karen S Sfanos Source Type: research
Effect of Moderate Malnutrition on the Pharmacokinetics of Etoposide and Vincristine in Freshly Weaned Rats
CONCLUSIONS: Our results suggest that while moderate malnutrition significantly affects the pharmacokinetics of etoposide, pharmacokinetics of vincristine remain unchanged. Since chemotherapy drugs have a narrow therapeutic index, the difference in AUC observed in our study might explain the increased toxicity of etoposide in malnourished pediatric cancer patients. This brings forth a need for robust clinical studies to validate our findings and optimize dose for malnourished patients.PMID:37700116 | DOI:10.1007/s13318-023-00851-7
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Megha Garg Khushboo Gandhi Shraddha Mahesh Jadhav Murari Gurjar Vikram Gota Source Type: research
The combination of quercetin and leucine synergistically improves grip strength by attenuating muscle atrophy by multiple mechanisms in mice exposed to cisplatin
In conclusion, this study suggests that the combination of quercetin and leucine enhanced the suppressed effects on CDDP-induced muscle weakness and CRF through downregulating muscle atrophy and upregulating the glycogen level in muscle tissues without compromising the anticancer effect of CDDP. Multiple mechanisms, including regulation of several signaling pathways and decrease in proinflammatory mediator levels in muscles may contributed to the enhanced protective effect of the combined treatments on muscle atrophy.PMID:37699022 | DOI:10.1371/journal.pone.0291462
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Te-Hsing Hsu Ting-Jian Wu Yu-An Tai Chin-Shiu Huang Jiunn-Wang Liao Shu-Lan Yeh Source Type: research
Impact of Successful Implementation of an Enhanced Recovery After Surgery Protocol for Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
CONCLUSIONS: Despite the heterogeneity of CRS/HIPEC operations, implementing an ERAS protocol for our patients was feasible and resulted in postoperative outcomes and adherence comparable with that of other major abdominal surgeries. This supports the potential for success in ERAS programs for CRS/HIPEC patients.PMID:37684372 | DOI:10.1245/s10434-023-14222-8
Source: Ann Oncol - September 8, 2023 Category: Cancer & Oncology Authors: Beatrice J Sun Tiffany M Yue Nova Xu Cedar Fowler Byrne Lee Source Type: research
Protein intake in cancer: Does it improve nutritional status and/or modify tumour response to chemotherapy?
CONCLUSIONS: Using a realistic model of cancer and chemotherapy, we demonstrated for the first time that protein intake did not positively or negatively modulate tumour growth. Moreover, our results suggested that a high cumulative protein intake was able to improve moderately nutritional status in chemotherapy treated cancer rodents. Although this work cannot be evaluated clinically for ethical reasons, it nevertheless brings an essential contribution to nutrition management for cancer patients.PMID:37667552 | DOI:10.1002/jcsm.13276
Source: Cancer Control - September 5, 2023 Category: Cancer & Oncology Authors: Martin Bouti ère C écile Cottet-Rousselle C éline Coppard Karine Couturier Catherine F éart Morgane Couchet Christelle Corne Christophe Moinard Charlotte Breuillard Source Type: research
Randomized Trial of Exercise and Nutrition on Chemotherapy Completion and Pathologic Complete Response in Women With Breast Cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis Study
CONCLUSION: Although a diet and exercise intervention did not affect RDI, the intervention was associated with a higher pCR in patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative and triple-negative breast cancer undergoing neoadjuvant chemotherapy.PMID:37656930 | DOI:10.1200/JCO.23.00871
Source: Clinical Genitourinary Cancer - September 1, 2023 Category: Cancer & Oncology Authors: Tara Sanft Maura Harrigan Courtney McGowan Brenda Cartmel Michelle Zupa Fang-Yong Li Leah M Ferrucci Leah Puklin Anlan Cao Thai Hien Nguyen Marian L Neuhouser Dawn L Hershman Karen Basen-Engquist Beth A Jones Tish Knobf Anees B Chagpar Andrea Silber Anna Source Type: research
Gut Microbiome and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):56-62. doi: 10.4166/kjg.2023.089.ABSTRACTColorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors that may increase the risk of CRC include obesity and consumption of a high-fat diet, red meat, processed meat, and alcohol. Recently, the role of gut microbiota in the formation, progression and treatment of CRCs has been investigated in depth. An altered gut microbiota can drive carcinogenesis and cause the development of CRC. Studies have also shown ...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Tae-Geun Gweon Source Type: research
