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"Hi, How Can I Help You?" Embracing Artificial Intelligence in Kidney Research
Am J Physiol Renal Physiol. 2023 Aug 17. doi: 10.1152/ajprenal.00177.2023. Online ahead of print.ABSTRACTIn recent years, biology and precision medicine have benefited from the major advancements in generating large-scale molecular and biomedical datasets and in analyzing those data using advanced machine learning algorithms. Machine learning applications in kidney physiology and pathophysiology include segmenting kidney structures from imaging data and predicting conditions like acute kidney injury or chronic kidney disease using electronic health records. Despite the potential of machine learning to revolutionize nephrol...
Source: Am J Physiol Renal P... - August 17, 2023 Category: Urology & Nephrology Authors: Anita T Layton Source Type: research
Fruit flies' ability to sense magnetic fields thrown into doubt
In this episode:00:49 The search for animals’ magnetic sense sufferers a potential setbackExactly how animals sense Earth’s magnetic field has long eluded researchers. To understand it, many have turned to the fly model Drosophila melanogaster, long thought to be able to detect magnetic fields. However, a recent Nature paper has raised questions about this ability, a finding that could have repercussions for scientists’ efforts to understand the mechanism behind magnetic sensing, one of the biggest questions in sensory biology.Research article: Bassetto et al.News & Views: Replication study casts doubt on magneti...
Source: Nature Podcast - August 16, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Greater executive dysfunction in patients post-COVID-19 compared to those not infected
Brain Behav Immun. 2023 Aug 14:S0889-1591(23)00237-4. doi: 10.1016/j.bbi.2023.08.014. Online ahead of print.ABSTRACTBACKGROUND: A number of patients post-coronavirus disease-19 (COVID-19) report cognitive impairment (CI), even months after acute infection. We aimed to assess if COVID-19 is associated with increased incidence of CI in comparison to controls.METHODS: We analyzed data from the Mount Sinai Health System Post-COVID-19 Registry in New York City, a prospective cohort of patients post-COVID-19 ≥18 years of age and non-infected controls. CI was defined by scores ≥1.0 standard deviation below population norms, a...
Source: Brain, Behavior, and Immunity - August 16, 2023 Category: Neurology Authors: Jacqueline H Becker Jenny J Lin Akosua Twumasi Ruchir Goswami Fernando Carnavali Kimberly Stone Monica Rivera-Mindt Minal S Kale Georges Naasan Joanne R Festa Juan P Wisnivesky Source Type: research
Folate deficiency increases the incidence of dolutegravir-associated foetal defects in a mouse pregnancy model
EBioMedicine. 2023 Aug 14;95:104762. doi: 10.1016/j.ebiom.2023.104762. Online ahead of print.ABSTRACTBACKGROUND: Dolutegravir (DTG) is a recommended first-line regimen for all people with Human Immunodeficiency Virus (HIV) infection. Initial findings from Botswana, a country with no folate fortification program, showed an elevated prevalence of neural tube defects (NTDs) with peri-conceptional exposure to DTG. Here we explore whether a low folate diet influences the risk of DTG-associated foetal anomalies in a mouse model.METHODS: C57BL/6 mice fed a folate-deficient diet for 2 weeks, were mated and then randomly allocated ...
Source: Cancer Control - August 16, 2023 Category: Cancer & Oncology Authors: Haneesha Mohan Jessica Nguyen Ben MacKenzie Audrey Yee Evelyn Yukino Laurette Tanvi Sanghvi Oscar Tejada Valeriya Dontsova Kit-Yi Leung Cameron Goddard Taylor De Young John G Sled Nicholas D E Greene Andrew J Copp Lena Serghides Source Type: research
Greater executive dysfunction in patients post-COVID-19 compared to those not infected
Brain Behav Immun. 2023 Aug 14:S0889-1591(23)00237-4. doi: 10.1016/j.bbi.2023.08.014. Online ahead of print.ABSTRACTBACKGROUND: A number of patients post-coronavirus disease-19 (COVID-19) report cognitive impairment (CI), even months after acute infection. We aimed to assess if COVID-19 is associated with increased incidence of CI in comparison to controls.METHODS: We analyzed data from the Mount Sinai Health System Post-COVID-19 Registry in New York City, a prospective cohort of patients post-COVID-19 ≥18 years of age and non-infected controls. CI was defined by scores ≥1.0 standard deviation below population norms, a...
Source: Brain, Behavior, and Immunity - August 16, 2023 Category: Neurology Authors: Jacqueline H Becker Jenny J Lin Akosua Twumasi Ruchir Goswami Fernando Carnavali Kimberly Stone Monica Rivera-Mindt Minal S Kale Georges Naasan Joanne R Festa Juan P Wisnivesky Source Type: research
Industry-Sponsored Research Funding to Rheumatologists in the United States Between 2014 and 2022
J Rheumatol. 2023 Aug 15:jrheum.2023-0417. doi: 10.3899/jrheum.2023-0417. Online ahead of print.ABSTRACTRheumatologists are responsible for conducting research on, managing, and treating major autoimmune diseases (AIDs) such as rheumatoid arthritis (RA), systemic lupus erythematosus, and psoriasis. AIDs afflict up to 23.5 million people in the United States.PMID:37582555 | DOI:10.3899/jrheum.2023-0417
Source: J Rheumatol - August 15, 2023 Category: Rheumatology Authors: Anju Murayama Source Type: research
