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Total 21 results found since Jan 2013.

Merck locates frozen batch of undisclosed Ebola vaccine, will donate for testing in Uganda ’s outbreak
In a revelation that may help Uganda combat its outbreak of Ebola, the pharmaceutical giant Merck has acknowledged to Science— after repeated inquiries — that it has up to 100,000 doses of an experimental vaccine for the deadly viral disease in its freezers in Pennsylvania and will donate them. The World Health Organization (WHO) and the Ugandan government are discussing if and how these doses can be incorporated into one or more clinical trials of other candidate Ebola vaccines that could launch as soon as next month. The Merck vaccine targets Sudan ebolavirus, the pathogen currently circulating...
Source: ScienceNOW - October 23, 2022 Category: Science Source Type: news

A subtractive proteomics and immunoinformatics approach towards designing a potential multi-epitope vaccine against pathogenic Listeriamonocytogenes
Microb Pathog. 2022 Sep 20:105782. doi: 10.1016/j.micpath.2022.105782. Online ahead of print.ABSTRACTListeria monocytogenes is the causative agent of listeriosis, which is dangerous for pregnant women, the elderly or individuals with a weakened immune system. Individuals with leukaemia, cancer, HIV/AIDS, kidney transplant and steroid therapy suffer from immunological damage are menaced. World Health Organization (WHO) reports that human listeriosis has a high mortality rate of 20-30% every year. To date, no vaccine is available to treat listeriosis. Thereby, it is high time to design novel vaccines against L. monocytogenes...
Source: Cancer Control - September 23, 2022 Category: Cancer & Oncology Authors: Shakilur Rahman Amit Kumar Das Source Type: research

The battle against malaria in Africa has stalled. Can research in Mozambique explain why?
.news-article__hero--featured .parallax__element{ object-position: 45% 50%; -o-object-position: 45% 50%; } .news-article__figure.inset { float: right !important; width: 33%; margin: 0.5rem 0 0.5rem 1rem; } @media (min-width: 576px) { .news-article__figure.inset { width: 25%; margin: 0.5rem 0 0.5rem 2rem; } } @media (min-width: 768px) { .news-article__figure.inset { width: 40%; margin: 0.5rem 0 0.5rem 1rem; } } Moisés Mapanga, a burly man of 49, is the bait. At 6 p.m. on a mid-April evening, he climbs into an orange tent outside his one-room house in Matutuíne, a hot, swampy district near Maputo, the cap...
Source: Science of Aging Knowledge Environment - September 8, 2022 Category: Geriatrics Source Type: research

Cervical cancer prevention in countries with the highest HIV prevalence: a review of policies
CONCLUSION: Considerable progress has been made in policy development for CC prevention and control in sub Saharan Africa. However, in countries with a high HIV burden, there is need to tailor these policies to respond to the specific needs of WLHIV. Countries may consider updating policies using the recent WHO guidelines for CC prevention, while adapting them to context realities.PMID:35948944 | DOI:10.1186/s12889-022-13827-0
Source: Cancer Control - August 10, 2022 Category: Cancer & Oncology Authors: Serra Lem Asangbeh-Kerman Ma ša Davidović Katayoun Taghavi James Kachingwe Kereng Molly Rammipi Laura Muzingwani Magaret Pascoe Marielle Jousse Masangu Mulongo Mulindi Mwanahamuntu Neo Tapela Oluwasanmi Akintade Partha Basu Xolisile Dlamini Julia Bohliu Source Type: research

The Virus Hunters Trying to Prevent the Next Pandemic
Nobody saw SARS-CoV-2 coming. In the early days of the pandemic, researchers were scrambling to collect samples from people who had mysteriously developed fevers, coughs, and breathing problems. Pretty soon, they realized that the disease-causing culprit was a new virus humans hadn’t seen before. And the world, lacking a coordinated global response, was unprepared. Some countries acted quickly to develop tests for the novel coronavirus, while others with fewer resources were left behind. With a virus oblivious to national borders, and with travel between countries and continents more common than it had been in previo...
Source: TIME: Health - August 1, 2022 Category: Consumer Health News Authors: Alice Park and Video by Andrew D. Johnson Tags: Uncategorized Disease Frontiers of Medicine 2022 healthscienceclimate Source Type: news

HIV / AIDS as a model for emerging infectious disease: origin, dating and circumstances of an emblematic epidemiological success
Presse Med. 2022 May 24:104128. doi: 10.1016/j.lpm.2022.104128. Online ahead of print.ABSTRACTIn June 1981, the Centers for Disease Control (CDC) "Morbidity and Mortality Weekly Report" described the first cases of what was to be known as the Acquired Immunodeficiency Syndrome (AIDS). Two years later, the agent responsible for the disease, the human immunodeficiency virus (HIV), was identified. Since then, according to the World Health Organization an estimated 40 million people have died from the disease. Where does this virus come from, and why such an emergence in the late 20th century? These are the questions that it i...
Source: Presse Medicale - May 27, 2022 Category: General Medicine Authors: Francis Barin Source Type: research

Male circumcision and Sexually transmitted Infections & #8211; An update
Kajal S Mehta, Yogesh S Marfatia, Apexa P Jain, Dhiral J Shah, Disha S BaxiIndian Journal of Sexually Transmitted Diseases and AIDS 2021 42(1):1-6Role of male circumcision (MC) as a tool to prevent sexually transmitted infections (STIs)/human immunodeficiency virus (HIV) was assessed. An attempt was made to search articles related to association between MC and STIs/HIV. A thorough search was carried out to find out quality articles published in indexed specialty journals. Centers for Disease Control and Prevention and World Health Organization (WHO) sites were also referred. Warm and moist environment of area under foreski...
Source: Indian Journal of Sexually Transmitted Diseases - May 4, 2021 Category: Infectious Diseases Authors: Kajal S Mehta Yogesh S Marfatia Apexa P Jain Dhiral J Shah Disha S Baxi Source Type: research

Expanding Research Capacity in Sub-Saharan Africa Through Informatics, Bioinformatics, and Data Science Training Programs in Mali
Conclusion Bioinformatics and data science training programs in developing countries necessitate incremental and collaborative strategies for their feasible and sustainable development. The progress described here covered decades of collaborative efforts centered on training and research on computationally intensive topics. These efforts laid the groundwork and platforms conducive for hosting a bioinformatics and data science training program in Mali. Training programs are perhaps best facilitated through Africa’s university systems as they are perhaps best positioned to maintain core resources during lapses in sho...
Source: Frontiers in Genetics - April 11, 2019 Category: Genetics & Stem Cells Source Type: research