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Vaccination: Covid Vaccine
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Total 722 results found since Jan 2013.
Comparative effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in immunocompromised individuals: a systematic review and meta-analysis using the GRADE framework
ConclusionThis GRADE meta-analysis based on a large number of consistent observational studies showed that the mRNA-1273 COVID-19 vaccine is associated with improved clinical effectiveness in IC populations compared with BNT162b2.
Source: Frontiers in Immunology - September 12, 2023 Category: Allergy & Immunology Source Type: research
Stem cell-based therapy for COVID-19
Int Immunopharmacol. 2023 Sep 7;124(Pt A):110890. doi: 10.1016/j.intimp.2023.110890. Online ahead of print.ABSTRACTWhile The World Health Organization (WHO) has announced that COVID-19 is no longer a public health emergency of international concern(PHEIC), the risk of reinfection and new emerging variants still makes it crucial to study and work towards the prevention of COVID-19. Stem cell and stem cell-like derivatives have shown some promising results in clinical trials and preclinical studies as an alternative treatment option for the pulmonary illnesses caused by the COVID-19 and can be used as a potential vaccine. In...
Source: International Immunopharmacology - September 9, 2023 Category: Allergy & Immunology Authors: Xiaomei Chen Bowen Liu Chao Li Yulian Wang Suxia Geng Xin Du Jianyu Weng Peilong Lai Source Type: research
Progress Toward Measles Elimination - African Region, 2017-2021
MMWR Morb Mortal Wkly Rep. 2023 Sep 8;72(36):985-991. doi: 10.15585/mmwr.mm7236a3.ABSTRACTWorldwide, measles remains a major cause of disease and death; the highest incidence is in the World Health Organization African Region (AFR). In 2011, the 46 AFR member states established a goal of regional measles elimination by 2020; this report describes progress during 2017-2021. Regional coverage with a first dose of measles-containing vaccine (MCV) decreased from 70% in 2017 to 68% in 2021, and the number of countries with ≥95% coverage decreased from six (13%) to two (4%). The number of countries providing a second MCV dose ...
Source: MMWR Morb Mortal Wkl... - September 7, 2023 Category: Epidemiology Authors: Balcha G Masresha Cynthia Hatcher Emmaculate Lebo Patricia Tanifum Ado M Bwaka Anna A Minta Sebastien Antoni Gavin B Grant Robert T Perry Patrick O'Connor Source Type: research
Factors that impact on recruitment to vaccine trials in the context of a pandemic or epidemic: a qualitative evidence synthesis
CONCLUSIONS: This review identifies many of the factors that influence a person's decision to take part in a vaccine trial, and these reflect findings from reviews that examine trials more broadly. However, we also recognise some factors that become more important in connection with a vaccine trial in the context of a pandemic or epidemic. These factors include the potential stigma of taking part, the possible adverse effects of a vaccine, the added motivation for helping society, the role of community leaders in trial dissemination, and the level of trust placed in governments and companies developing vaccines. These spec...
Source: Cochrane Database of Systematic Reviews - September 1, 2023 Category: General Medicine Authors: Pauline Meskell Linda M Biesty Maura Dowling Kevin Roche Elaine Meehan Claire Glenton Declan Devane Sasha Shepperd Andrew Booth Rebecca Cox Xin Hui S Chan Catherine Houghton Source Type: research
Active surveillance of adverse events following COVID-19 vaccines in a tertiary care hospital
CONCLUSION: The study identified only 0.33% of events as serious, and 99.67% of the study population recovered from the AEFIs, which reveals that COVISHIELD™ and COVAXIN® have a generally favourable safety profile. However, close monitoring is required to identify the potential signals, as the safety data from the clinical trials are limited.PMID:37641637 | PMC:PMC10460577 | DOI:10.1177/25151355231193975
Source: Adv Data - August 29, 2023 Category: Epidemiology Authors: Naveena Mary Cherian Dravya Anna Durai Muhammed Jaisel Divyansh Sharma Juny Sebastian Chetak Kadabasal Basavaraja Merrin Mathew Source Type: research
A comprehensive review on the global efforts on vaccines and repurposed drugs for combating COVID-19
Eur J Med Chem. 2023 Aug 10;260:115719. doi: 10.1016/j.ejmech.2023.115719. Online ahead of print.ABSTRACTThe recently discovered coronavirus, known as SARS-CoV-2, is a highly contagious and potentially lethal viral infection that was declared a pandemic by the World Health Organization on March 11, 2020. Since the beginning of the pandemic, an unprecedented number of COVID-19 vaccine candidates have been investigated for their potential to manage the pandemic. Herein, we reviewed vaccine development and the associated research effort, both traditional and forward-looking, to demonstrate the advantages and disadvantages of ...
Source: European Journal of Medicinal Chemistry - August 19, 2023 Category: Chemistry Authors: Narva Deshwar Kushwaha Jivanka Mohan Babita Kushwaha Terisha Ghazi Joshua C Nwabuife Neil Koorbanally Anil A Chuturgoon Source Type: research
